Contrast-enhanced computed tomography findings of canine primary renal tumors including renal cell carcinoma, lymphoma, and hemangiosarcoma

English version

Autoři: Toshiyuki Tanaka ^aff001; Hideo Akiyoshi ^aff001; Hidetaka Nishida ^aff001; Keiichiro Mie ^aff001; Lee-Shuan Lin ^aff003; Yasumasa Iimori ^aff001; Mari Okamoto ^aff001
Působiště autorů: Laboratory of Veterinary Surgery, Osaka Prefecture University, Department of Graduate School of Life and Environmental Sciences, Osaka, Japan ^aff001; Kinki Animal Medical Training Institute and Veterinary Clinic, Osaka, Japan ^aff002; Laboratory of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Department of Veterinary Medicine, National Pingtung University of Science and Technology, Neipu, Taiwan ^aff003
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0225211

Souhrn

In veterinary medicine, abdominal ultrasonography is used to rank the differential diagnosis of renal lesions. However, a conventional sonographic examination may show nonspecific findings. The purpose of this study was to assess the computed tomography (CT) findings of canine renal tumors, including renal cell carcinoma (RCC), lymphoma, and hemangiosarcoma (HSA). In this retrospective study, the following CT parameters were recorded for each dog: 1) extent of renal involvement of tumors, 2) enhancement pattern, 3) number of renal tumors, 4) renal tumor vessel enhancement in the corticomedullary phase, 5) presence of lymphadenopathy and lung metastasis, and 6) attenuation values of the renal tumors on the pre- and post-contrast corticomedullary, nephrographic, and excretory phase images. Fifteen dogs met the inclusion criteria, of which nine had RCCs, four had lymphomas, and two had HSAs. RCCs tended to show heterogeneous enhancement and unilateral renal involvement, and vessel enhancement was detected in the corticomedullary phase in dogs with RCC. Conversely, renal lymphomas showed homogeneous enhancement, bilateral renal involvement, and multiple masses; in these dogs, no vessel enhancement was detected in the corticomedullary phase, and the incidence of lymphadenopathy was low. However, in dogs with lymphadenopathy, the renal lymphoma was associated with regionally severe lymphadenopathy. Finally, renal HSAs tended to show heterogeneous enhancement with a non-enhanced area and unilateral renal involvement; in these dogs, vessel enhancement was detected in the nephrographic phase, with the enhancement expanding around the vessel. These findings had no significant differences. Further studies with a larger sample size are required to examine the association between CT and histopathological findings.

Klíčová slova:

Dogs – Cancer detection and diagnosis – Computed axial tomography – Metastasis – Veterinary diagnostics – Lymphomas – Renal cell carcinoma – Renal cancer

Zdroje

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Contrast-enhanced computed tomography findings of canine primary renal tumors including renal cell carcinoma, lymphoma, and hemangiosarcoma

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