Toddler skills predict moderate-to-late preterm born children’s cognition and behaviour at 6 years of age

English version

Autoři: Lilly Bogičević ^aff001; Marjolein Verhoeven ^aff001; Anneloes L. van Baar ^aff001
Působiště autorů: Child and Adolescent Studies, Utrecht University, Utrecht, Netherlands ^aff001
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0223690

Souhrn

Objective

To compare moderate-to-late preterm born (32–36 weeks’ gestation) to full term born (≥37 weeks’ gestation) children in cognitive and behavioural functioning at the age of 6 years and assess which toddler skills predict later cognitive and behavioural functioning.

Design

A prospective longitudinal study with a cohort of 88 moderate-to-late preterm and 83 full term born Dutch children, followed from 18 months to 6 years of age. Orienting, alerting and executive attention skills were assessed at 18 months (corrected for prematurity), and cognitive, motor and language skills (Bayley-III-NL) at 24 months (corrected for prematurity). At 6 years (corrected for prematurity), cognitive (indices of IQ; WPPSI-III-NL) and behavioural functioning (CBCL/6-18) were assessed. Group differences and potential predictors were examined with MANCOVAs and hierarchical regression analyses.

Results

At 6 years, moderate-to-late preterm born children performed poorer than full term born children on cognitive processing speed, and they showed more behavioural attention problems. Attention problems at 6 years were predicted by poorer orienting attention skills at 18 months, while lower performance IQ was predicted by poorer alerting attention skills at 18 months. Full Scale IQ and Verbal IQ at 6 years were predicted by language skills at 24 months. Moderate-to-late preterm and full term born children showed some differing correlational patterns in the associations between early skills and later functioning, although in further analyses predictors appeared the same for both groups.

Conclusions

Moderate-to-late preterm born children show specific vulnerabilities at primary school-age, particularly in cognitive processing speed and behavioural attention problems. Cognitive and behavioural functioning at 6 years can be predicted by differentiated attention skills at 18 months and language skills at 24 months.

Klíčová slova:

Behavior – Children – Cognition – Attention – Intelligence – Language – Cognitive linguistics – Toddlers

Zdroje

1. Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller A-B, Narwal R, et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. The Lancet 2012;379(9832):2162–72.

2. Tomashek KM, Shapiro-Mendoza CK, Davidoff MJ, Petrini JR. Differences in mortality between late-preterm and term singleton infants in the United States, 1995–2002. J Pediatr 2007;151(5):450–6. doi: 10.1016/j.jpeds.2007.05.002 17961684

3. Shapiro-Mendoza CK, Tomashek KM, Kotelchuck M, Barfield W, Nannini A, Weiss J, et al. Effect of late-preterm birth and maternal medical conditions on newborn morbidity risk. Pediatrics 2008;121(2):223–32.

4. Chan E, Leong P, Malouf R. Long-term cognitive and school outcomes of late-preterm and early-term births: a systematic review. Child Care Health Dev 2016;42(3):297–312. doi: 10.1111/cch.12320 26860873

5. De Jong M, Verhoeven M, Van Baar AL. School outcome, cognitive functioning, and behaviour problems in moderate and late preterm children and adults: a review. Semin Fetal Neonatal Med 2012;17(3):163–9. doi: 10.1016/j.siny.2012.02.003 22364677

6. Cserjesi R, Koenraad NJA, Van Braeckel KN, Butcher PR, Kerstjens JM, Sijmen AR, et al. Functioning of 7-year-old children born at 32 to 35 weeks' gestational age. Pediatrics 2012;130(4):838–46

7. Nomura Y, Halperin JM, Newcorn JH, Davey C, Fifer WP, Savitz DA, et al. The risk for impaired learning-related abilities in childhood and educational attainment among adults born near-term. J Pediatr Psychol 2009;34(4):406–18. doi: 10.1093/jpepsy/jsn092 18794190

8. Talge NM, Holzman C, Wang J, Lucia V, Gardiner J, Breslau N. Late-preterm birth and its association with cognitive and socioemotional outcomes at 6 years of age. Pediatrics 2010;126(6):1124–31. doi: 10.1542/peds.2010-1536 21098151

9. Van Baar AL, Vermaas J, Knots E, De Kleine MJK, Soons P. Functioning at school age of moderately preterm children born at 32 to 36 weeks' gestational age. Pediatrics 2009;124(1):251–7. doi: 10.1542/peds.2008-2315 19564307

10. De Jong M, Verhoeven M, Van Baar AL. Attention capacities of preterm and term born toddlers: A multi-method approach. Early Hum Dev 2015;91(12):761–8. doi: 10.1016/j.earlhumdev.2015.08.015 26432180

11. De Jong M, Verhoeven M, Lasham CA, Meijssen CB, Van Baar AL. Behavior and development in 24-month-old moderately preterm toddlers. Arch Dis Child Fetal Neonatal Ed 2015;100:548–53.

12. Lawson KR, Ruff HA. Early focused attention predicts outcome for children born prematurely. Dev Behav Pediatr 2004;25(6):399–406.

13. Ribeiro LA, Zachrisson HD, Schjolberg S, Aase H, Rohrer-Baumgartner N, Magnus P. Attention problems and language development in preterm low-birth-weight children—Cross-lagged relations from 18 to 36 months. BMC Pediatrics 2011;59(11).

14. Romeo DM, Guzzardi S, Ricci D, Cilauro S, Brogna C, Cowan F, et al. Longitudinal cognitive assessment in healthy late preterm infants. Eur J Paediatr Neurol 2012;16(3):243–7. doi: 10.1016/j.ejpn.2011.07.012 21944394

15. Potharst ES, Houtzager BA, Van Sonderen L, Tamminga P, Kok JH, Last BF, et al. Prediction of cognitive abilities at the age of 5 years using developmental follow-up assessments at the age of 2 and 3 years in very preterm children. Dev Med Child Neurol 2012;54(3):240–6. doi: 10.1111/j.1469-8749.2011.04181.x 22188215

16. Marchman VA, Loi EC, Adams KA, Ashland M, Fernald A, Feldman HM. Speed of language comprehension at 18 months old predicts school-relevant outcomes at 54 months old in children born preterm. J Dev Behav Pediatr 2018;39(3):246–53. doi: 10.1097/DBP.0000000000000541 29309294

17. Piek JP, Dyck MJ, Nieman A, Anderson M, Hay D, Smith LM, et al. The relationship between motor coordination, executive functioning and attention in school aged children. Arch Clin Neuropsychol 2004;19(8):1063–76. doi: 10.1016/j.acn.2003.12.007 15533697

18. Piek JP, Barrett NC, Smith LM, Rigoli D, Gasson N. Do motor skills in infancy and early childhood predict anxious and depressive symptomatology at school age? Hum Mov Sci 2010;29(5):777–86. doi: 10.1016/j.humov.2010.03.006 20650535

19. Stichting Perinatale Registratie Nederland. Referentiecurven. http://www.perinatreg.nl/referentiecurven (accessed 25 Apr 2014).

20. De Jong M, Verhoeven M, Hooge ITC, Van Baar AL. Introduction of the Utrecht Tasks for Attention in Toddlers Using Eye Tracking (UTATE): A pilot study. Front Psychol 2016;7:669. doi: 10.3389/fpsyg.2016.00669 27199880

21. De Jong M, Verhoeven M, Hooge ITC, Van Baar AL. Factor structure of attention capacities measured with eye-tracking tasks in 18-month-old toddlers. J Atten Disord 2016;20(3):230–9. doi: 10.1177/1087054713516002 24366780

22. Posner MI, Petersen SE (1990). The attention system of the human brain. Annu Rev Neurosci 1990;13:25–42. doi: 10.1146/annurev.ne.13.030190.000325 2183676

23. Rosseel Y. lavaan: An R Package for Structural Equation Modeling. Journal of Statistical Software, 2012;48(2), 1–36. http://www.jstatsoft.org/v48/i02/

24. R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. 2018; http://www.R-project.org/.

25. Hu L, Bentler PM. Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Struct Equ Modeling 1999;6:1–55.

26. Van Baar AL, Steenis LJP, Verhoeven M. Bayley Scales of Infant and Toddler Development—Derde Editie, Nederlandstalige bewerking, Technische handleiding. Amsterdam: Pearson Assessment and Information B.V., 2014.

27. Hendriksen J, Hurks P. Wechsler Primary and Preschool Scale of Intelligence—Derde Editie, Nederlandstalige bewerking: Technische handleiding, 2nd ed., Amsterdam: Pearson Assessment and Information B.V., 2010.

28. Verhulst FC, Van der Ende J. Handleiding ASEBA-Vragenlijsten voor leeftijden 6 t/m 18 jaar: CBCL6/18, YSR en TRF. Rotterdam: Erasmus MC, 2013.

29. Van Veen S, Aarnoudse-Moens CS, Van Kaam AH, Oosterlaan J, Van Wassenaer-Leemhuis AG. Consequences of correcting intelligence quotient for prematurity at age 5 years. J Pediatr 2016;173:90–5. doi: 10.1016/j.jpeds.2016.02.043 26979649

30. Anderson PJ, Doyle LW. Neurobehavioral outcomes of school-age children born extremely low birth weight or very preterm in the 1990s. JAMA 2003;289:3264–3272. doi: 10.1001/jama.289.24.3264 12824207

31. Hall J, Jaekel J, Wolke D. Gender distinctive impacts of prematurity and small for gestational age (SGA) on age-6 attention problems. Child Adolesc Ment Health 2012;17(4):238–45.

32. Lean RE, Melzer TR, Bora S, Watts R, Woodward LJ. Attention and Regional Gray Matter Development in Very Preterm Children at Age 12 Years. Journal of the International Neuropsychological Society. 2017;23(7):539–550. doi: 10.1017/S1355617717000388 28566104

33. Mulder H, Pitchford NJ, Marlow N. Processing Speed Mediates Executive Function Difficulties in Very Preterm Children in Middle Childhood. Journal of the International Neuropsychological Society. 2011;17(3):445–454. doi: 10.1017/S1355617711000373 21439114

34. Murray AL, Scratch SE, Thompson DK, Inder TE, Doyle LW, Anderson JFI, et al. Neonatal brain pathology predicts adverse attention and processing speed outcomes in very preterm and/or very low birth weight children. Neuropsychology 2014; 28: 552–62 doi: 10.1037/neu0000071 24708047

35. Rose SA, Feldman JF, Jankowski JJ, Van Rossem R. Basic Information Processing Abilities at 11 years Account for Deficits in IQ Associated with Preterm Birth. Intelligence. 2011;39(4):198–209. doi: 10.1016/j.intell.2011.03.003 21643482