Acceleration of chemical shift encoding-based water fat MRI for liver proton density fat fraction and T2* mapping using compressed sensing
Autoři:
Fabian K. Lohöfer aff001; Georgios A. Kaissis aff001; Christina Müller-Leisse aff001; Daniela Franz aff001; Christoph Katemann aff002; Andreas Hock aff002; Johannes M. Peeters aff003; Ernst J. Rummeny aff001; Dimitrios Karampinos aff001; Rickmer F. Braren aff001
Působiště autorů:
Institute for diagnostic and interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Straße, München, Germany
aff001; Philips Healthcare, Hamburg, Germany
aff002; Philips Healthcare, Best, Netherlands
aff003
Vyšlo v časopise:
PLoS ONE 14(11)
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pone.0224988
Souhrn
Objectives
To evaluate proton density fat fraction (PDFF) and T2* measurements of the liver with combined parallel imaging (sensitivity encoding, SENSE) and compressed sensing (CS) accelerated chemical shift encoding-based water-fat separation.
Methods
Six-echo Dixon imaging was performed in the liver of 89 subjects. The first acquisition variant used acceleration based on SENSE with a total acceleration factor equal to 2.64 (acquisition labeled as SENSE). The second acquisition variant used acceleration based on a combination of CS with SENSE with a total acceleration factor equal to 4 (acquisition labeled as CS+SENSE). Acquisition times were compared between acquisitions and proton density fat fraction (PDFF) and T2*-values were measured and compared separately for each liver segment.
Results
Total scan duration was 14.5 sec for the SENSE accelerated image acquisition and 9.3 sec for the CS+SENSE accelerated image acquisition. PDFF and T2* values did not differ significantly between the two acquisitions (paired Mann-Whitney and paired t-test P>0.05 in all cases). CS+SENSE accelerated acquisition showed reduced motion artifacts (1.1%) compared to SENSE acquisition (12.3%).
Conclusion
CS+SENSE accelerates liver PDFF and T2*mapping while retaining the same quantitative values as an acquisition using only SENSE and reduces motion artifacts.
Klíčová slova:
Fats – Imaging techniques – Magnetic resonance imaging – Image processing – Fatty liver – Steatosis – Liver and spleen scan – Compressed sensing
Zdroje
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PLOS One
2019 Číslo 11
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