What is the optimum time for initiation of early mobilization in mechanically ventilated patients? A network meta-analysis
Autoři:
Nannan Ding aff001; Zhigang Zhang aff001; Caiyun Zhang aff001; Li Yao aff001; Liping Yang aff001; Biantong Jiang aff001; Yuchen Wu aff001; Lingjie Jiang aff001; Jinhui Tian aff004
Působiště autorů:
School of Nursing, Lanzhou University, Lanzhou, China
aff001; Intensive Care Unit, The First Hospital of Lanzhou University, Lanzhou, China
aff002; Department of Nursing, The First Hospital of Lanzhou University, Lanzhou, China
aff003; Evidence-Based Medicine Center, Lanzhou University, Lanzhou, China
aff004
Vyšlo v časopise:
PLoS ONE 14(10)
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pone.0223151
Souhrn
Early mobilization has been proven to be an effective and safe intervention for preventing complications in mechanically ventilated patients; however, there is currently no unified definition of the optimal mobilization initiation time, hindering widespread clinical implementation. As clinicians are increasingly aware of the benefits of early mobilization, the definition of early mobilization is important. The purpose of this study was to evaluate the effects of different early mobilization initiation times on mechanically ventilated patients and rank these times for practical consideration. The Chinese Biomedical Literature Database, the Chinese Knowledge Infrastructure, Wanfang Data, PubMed, Cochrane Library, Web of Science, and Embase databases, along with grey literature and reference lists, were searched for randomized control trials (RCTs) that evaluated the effects of early mobilization for improving patient outcomes; databases were searched from inception to October 2018. Two authors extracted data independently, using a predesigned Excel form, and assessed the quality of included RCTs according to the Cochrane Handbook (v5.1.0). Data were analyzed using Stata (v13.0) and Review Manager (v5.3.0). A total of 15 RCTs involving 1726 patients and seven mobilization initiation times (which were all compared to usual care) were included in our analysis. Network meta-analysis showed that mechanical ventilation for 48–72 h may be optimal to improve intensive care unit acquired weakness (ICU-AW) and reduce the duration of mechanical ventilation; however, there were no significant differences in length of ICU stay according to mobilization initiation time. The results of this study indicate that initiation of mobilization within 48–72 h of mechanical ventilation may be optimal for improving clinical outcomes for mechanically ventilated patients.
Klíčová slova:
Network analysis – Medicine and health sciences – Systematic reviews – Database searching – Intensive care units – Publication ethics – Chinese people
Zdroje
1. Castro-Avila AC, Serón P, Fan E, Gaete M, Mickan S. Effect of early rehabilitation during intensive care unit stay on functional status: systematic review and meta-analysis. PLoS ONE. 2015;10(7): e0130722. doi: 10.1371/journal.pone.0130722 26132803.
2. Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, et al. Acute skeletal muscle wasting in critical illness. JAMA. 2013;310(15): 1591. doi: 10.1001/jama.2013.278481 24108501.
3. Iwashyna TJ, Ely EW, Smith DM, Langa KM. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA. 2010;304(16): 1787. doi: 10.1001/jama.2010.1553 20978258.
4. Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial. Lancet. 2009;373(9678): 1874–1882. doi: 10.1016/S0140-6736(09)60658-9 19446324.
5. Yang LP, Zhang ZG, Zhang CY, Ma XJ, Tian JH, Zhang YH, et al. Effect of early mobilisation on the prevention of intensive care unit acquired weakness: A Meta-analysis. Nursing Journal of Chinese People's Liberation Army. 2018;35(05): 1–7.
6. Zhao GM, Jiao LL, Yang GH. The effects of early progressive exercise on ICU acquired weakness: a meta-analysis. Chinese Journal of Nursing. 2017;52(02): 177–181.
7. Bailey P, Thomsen GE, Spuhler VJ, Blair R, Jewkes J, Bezdjian L, et al. Early activity is feasible and safe in respiratory failure patients. Crit Care Med. 2007;35(1): 139–145. doi: 10.1097/01.CCM.0000251130.69568.87 17133183.
8. Harrold ME. Early mobilisation of mechanically ventilated adults in intensive care: implementation of practice change and benchmarking of practice. Perth: Curtin University, 2013.
9. Clarissa C, Salisbury L, Rodgers S, Kean S. Early mobilisation in mechanically ventilated patients: a systematic review of definitions and activities. J Intensive Care. 2019;7: 3. doi: 10.1186/s40560-018-0355-z 30680218
10. Morris PE, Goad A, Thompson C, Taylor K, Harry B, Passmore L, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36(8): 2238–2243. doi: 10.1097/CCM.0b013e318180b90e 18596631.
11. Moss M, Nordon-Craft A, Malone D, Van Pelt D, Frankel SK, Warner ML, et al. A randomized trial of an intensive physical therapy program for acute respiratory failure patients. Am J Respir Crit Care Med. 2016;193(10): 1101. doi: 10.1164/rccm.201505-1039OC 26651376.
12. Rehabilitation after critical illness in adults. National Institute for Health and Care Excellence (NICE). 2009. https://www.nice.org.uk/Guidance/CG832
13. Zeng XT, Cao SHY, Sun F, Tian GX. The sixth of meta analysis: Indirect comparison and network meta analysis. Chinese Journal of Evidence-Based Cardiovascular Medicine. 2012;4(05):309–402.
14. Rouse B, Chaimani A, Li T. Network meta-analysis: an introduction for clinicians[J]. Intern Emerg Med, 2017;12(1):103–111. doi: 10.1007/s11739-016-1583-7 27913917
15. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, et al. The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: Checklist and explanations. Ann Intern Med. 2015;162(11): 777–784. doi: 10.7326/M14-2385 26030634.
16. Hu Y. Evidence-based nursing. Beijing: People's Medical Publishing House, 2012: 351.
17. Fan E, Cheek F, Chlan L, Gosselink R, Hart N, Herridge MS, et al. An official American Thoracic Society clinical practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med. 2014;190(12): 1437–1446. doi: 10.1164/rccm.201411-2011ST 25496103
18. Hodgson CL, Bailey M, Bellomo R, Berney S, Buhr H, Denehy L, et al. A binational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in the ICU. Crit Care Med. 2016;44(6): 1145–1152. doi: 10.1097/CCM.0000000000001643 26968024.
19. Schaller SJ, Anstey M, Blobner M, Edrich T, Grabitz SD, Gradwohl-Matis, Heim M, et al. Early goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial. Lancet. 2016;388(10052):1377–1388. doi: 10.1016/S0140-6736(16)31637-3 27707496.
20. Dong ZH, Yu BX, Sun YB, Fang W, Li L. Effects of early rehabilitation therapy on patients with mechanical ventilation. World J Emerg Med. 2014;5(1): 48. doi: 10.5847/wjem.j.1920-8642.2014.01.008 25215147
21. Burtin C, Clerckx B, Robbeets C, Ferdinande P, Langer D, Troosters T, et al. Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med. 2009;37(9): 2499–2505. doi: 10.1097/CCM.0b013e3181a38937 19623052.
22. Denehy L, Skinner EH, Edbrooke L, Haines K, Warrillow S, Hawthorne G, et al. Exercise rehabilitation for patients with critical illness: a randomized controlled trial with 12 months of follow-up. Crit Care. 2013;17(4): R156. doi: 10.1186/cc12835 23883525.
23. Zhang AM, ding AP, Lu YH. Effect of early mobilisation in preventing ICU acquired weakness in patients with COPD mechanical ventilation. Nursing Journal of Chinese People's Liberation Army. 2017;34(15): 44–46.
24. Yu P, Ren GQ, Lu XM, Yang ZY, Li YT. Application of early activity and rehabilitation program in ICU mechanical ventilation patients. J Nurs Train. 2016;31(02): 161–164.
25. Hu HJ, Wei HY, Xu J, Chen Q. Effect of early mobilisation on patients with ICU acquired weakness. Nurs Res. 2014,28(27): 3378–3379.
26. Shao X. The relationship between early activity and the incidence of delirium of patients with mechanical ventilation in ICU. Zunyi Medical University. 2015.
27. Ke H, Huang HY. Effect of four-stage early activity and rehabilitation exercise therapy on prevention of ICU acquired weakness. Nurs Res. 2016;30(18): 2202–2205.
28. Huang HY, Wang XF, Luo J, H L, Zhou XJ. Effect of early level 4 rehabilitation training for patients with mechanical ventilation in ICU. J Nurs Sci. 2016;31(15): 1–5.
29. Yu LN. Effect of early exercise in intensive care unit acquired weakness. Dalian Medical University, 2013.
30. Stevens RD, Marshall SA, Cornblath DR, Hoke A, Needham DM, De Jonghe B, et al. A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med. 2009;37(10Suppl): S299–S308. doi: 10.1097/CCM.0b013e3181b6ef67 20046114.
31. De Jonghe B, Bastuji-Garin S, Sharshar T, Outin H, Brochard L. Does ICU-acquired paresis lengthen weaning from mechanical ventilation? Intensive Care Med. 2004;30(6): 1117–1121. doi: 10.1007/s00134-004-2174-z 14767593
32. Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, et al. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness: a cohort study and propensity-matched analysis. Am J Respir Crit Care Med. 2014;190(4): 410–420. doi: 10.1164/rccm.201312-2257OC 24825371
33. Weinert CR, Calvin AD. Epidemiology of sedation and sedation adequacy for mechanically ventilated patients in a medical and surgical intensive care unit. Crit Care Med. 2007;35(2): 393–401. doi: 10.1097/01.CCM.0000254339.18639.1D 17205015.
34. Rodriguez PO, Setten M, Maskin LP, Bonelli I, Vidomlansky SR, Attie S, et al. Muscle weakness in septic patients requiring mechanical ventilation: Protective effect of transcutaneous neuromuscular electrical stimulation. J Crit Care. 2012;27(3): 319.e1-8. doi: 10.1016/j.jcrc.2011.04.010 21715139.
35. Berek K, Margreiter J, Willeit J, Berek A, Schmutzhard E, Mutz NJ, et al. Polyneuropathies in critically ill patient: a prospective evaluation. Intensive Care Med. 1996;22(9): 849–855. doi: 10.1007/bf02044106 8905416.
36. Leijten F S, De Weerd AW, Poortvliet DC, De Ridder VA, Ulrich C, Harink-De Weerd JE, et al. Critical illness polyneuropathy in multiple organ dysfunction syndrome and weaning from the ventilator. Intensive Care Med. 1996;22(9): 856–861. doi: 10.1007/bf02044107 8905417.
37. Castro E, Turcinovic M, Platz J, Law I. Early mobilization: Changing the mindset. Crit Care Nurse. 2015;35(4): e1–5. doi: 10.4037/ccn2015512 26232809.
38. Engel HJ, Needham DM, Morris PE, Gropper MA. ICU early mobilization: from recommendation to implementation at three medical centers. Crit Care Med. 2013;41(9 Suppl 1): 69–80. doi: 10.1097/CCM.0b013e3182a240d5 23989097.
39. Jolley SE, Regan-Baggs J, Dickson RP, Hough CL. Medical intensive care unit clinician attitudes and perceived barriers towards early mobilisation of critically ill patients: a cross-sectional survey study. BMC Anesthesiol. 2014: 14–84. doi: 10.1186/1471-2253-14-14 25309124.
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