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preLekára.sk / Odborné časopisy / PLOS One / 2019 - 10

Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis

Authors: Goris Nazari aff001;  Joy C. MacDermid aff001;  Dianne Bryant aff001;  Neha Dewan aff004;  George S. Athwal aff002
Authors place of work: School of Physical Therapy, Faculty of Health Science, Western University, London, ON, Canada aff001;  Collaborative Program in Musculoskeletal Health Research, Bone and Joint Institute, Western University, London, ON Canada aff002;  Roth McFarlane Hand and Upper Limb Centre, St. Joseph’s Hospital, London, ON, Canada aff003;  Department of Health Sciences, Lakehead University, Canada aff004
Published in the journal: PLoS ONE 14(10)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0222953

Summary

Objective

To assess the effectiveness of arthroscopic versus mini-open rotator cuff repair on function, pain and range of motion at 3-, 6- and 12-month follow ups.

Design

Systematic review and meta-analysis of randomized controlled trials.

Setting

Clinical setting.

Participants

Patients 18 years and older with a rotator cuff tear.

Intervention/Comparison

Arthroscopic/mini-open rotator cuff repair surgery followed by post operative rehabilitation.

Main outcome measures

Function and pain.

Results

Six RCTs (n = 670) were included. The pooled results, demonstrated no significant difference between arthroscopic and mini open approach to rotator cuff repair on function (very low quality, 4 RCTs, 495 patients, SMD 0.00, 3-month; very low quality, 4 RCTs, 495 patients, SMD -0.01, 6-month; very low quality, 3 RCTs, 462 patients, SMD -0.09, 12-months). For pain, the pooled results, were not statistically different between groups (very low quality, 3 RCTs, 254 patients, MD -0.21, 3-month; very low quality, 3 RCTs, 254 patients, MD -0.03, 6-month; very low quality, 2 RCTs, 194 patients, MD -0.35, 12-months).

Conclusion

The effects of arthroscopic compared to mini-open rotator cuff repair, on function, pain and range of motion are too small to be clinically important at 3-, 6- and 12-month follow ups.

Keywords:

Systematic reviews – Surgical and invasive medical procedures – Publication ethics – Strength training – Randomized controlled trials – surgical repair – arthroscopy

Introduction

Across the general population, rotator cuff tears impact 1 in 5 individuals, and 1 in 3 of those with shoulder symptoms[1]. Rotator cuff tears are more prevalent in older adults, those involved in heavy labor, males as well as individuals with previous history of injury[1]. Studies have demonstrated that surgical interventions including mini-open or arthroscopic repairs to offer satisfactory outcomes [2–4]. The mini-open has been considered the gold standard technique, costs significantly less, and proved to attain good to excellent outcomes in 90% of patients [5–8]. On the other hand, factors such as lower postoperative pain, quicker recovery time, and superior cosmetic results have steered surgeons’ preferences to choosing an arthroscopic technique based on the to emerging evidence [9–11]. However, there is no consensus on whether one technique offers superior outcomes.

To date, three systematic reviews (SRs) have examined the effectiveness of clinical outcomes in patients with rotator cuff tears undergoing arthroscopic vs mini-open rotator cuff repairs [2–4] The Shan et al. (2014) review of 12 studies (3 RCTs, 9 observational), and the Huang et al. (2016) review of 18 studies (4 RCTs, 14 observational), both concluded that there were no differences in outcomes between the arthroscopic and mini-open rotator cuff repair techniques [2–3]. However, in these reviews, studies were pooled irrespective of their design (RCT and observational), which greatly limits our confidence in its effect estimates [2–3] Furthermore, the risk of bias in the included studies were not assessed. A third review by Ji et al. (2015), included 5 RCTs and again concluded that there were no differences in outcomes at the end of follow-up between the arthroscopic and mini-open rotator cuff repair techniques [4]

While the review by Ji et al. (2015) provides valuable insights, it has important limitations. For example, trials were pooled and meta-analyses conducted based on the last follow-up time point reported (range: 6–34 months), which might have in turn contributed to the high levels of heterogeneity in the pooled analyses [12]. The effectiveness of arthroscopic versus mini-open rotator cuff repair on outcomes function, pain and range of motion, at 3-, 6- and 12-month follow ups were not assessed. Furthermore, the review failed to provided ratings of the quality of the evidence across each outcome, according to Grading of Recommendations, Assessment, Development and Evaluation (GRADE) guidelines [13]. Therefore, the purpose of this review was to conduct a systematic review with meta-analysis that addresses the reported limitations of the aforementioned reviews.

The objectives of this review were

  • to quantify the effects of arthroscopic versus mini-open rotator cuff repair on function, pain and range of motion at 3-, 6- and 12-month follow ups,

  • to rate the quality of the body of literature that compares the effectiveness of arthroscopic versus mini-open rotator cuff repair according to GRADE guidelines across each outcome.

Methods

We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Cochrane collaboration guidelines [14–15]. (S1 PRISMA Checklist) PROSPERO registration number: CRD 42018097325.

Eligibility criteria

Studies were included in this systematic review if the below criteria were met [2–4]:

  • Design: randomized controlled trial (RCT) in English published in a peer reviewed journal between January 1998 –July 2019,

  • Participants: patients 18 years and older with a rotator cuff tear,

  • Intervention/ Comparison: trials that compared patients who underwent arthroscopic or mini-open rotator cuff repair followed by post operative rehabilitation,

  • Outcomes: function/disability, pain and shoulder range of motion.

Studies that included patients with degenerative arthritis, rheumatoid arthritis of glenohumeral joint, adhesive capsulitis/ shoulder fractures / previous surgery, that were conference abstract and posters were excluded from this systematic review [2–4].

Information sources

We conducted systematic electronic searches to identify relevant randomized controlled trials in MEDLINE, EMBASE, CINAHL and Google scholar from January 1998 to July 2019. Several different combinations of keywords were used, such as: “rotator cuff repair”, “randomized controlled trials”, “arthroscopic surgery”, “mini-open surgery”, “rehabilitation after arthroscopic”, “rehabilitation after mini-open”, “effectiveness of arthroscopic”, “effectiveness of mini-open”. In addition, we also performed a search in the clinical trial registers catalogues (ClinicalTrials.gov, EU registry and ISRCTN registry), and carried out a manual search of the reference lists of the previous systematic reviews and the references of all the included articles.

Study selection

Two independent reviewers (GN and ND) carried out the systematic electronic searches in each database. Duplicate studies were identified and removed. Next, we independently screened the titles and abstracts and retrieved in full text any article marked include or uncertain by either reviewer. Finally, we conducted an independent full text review to determine final eligibility. In case of disagreement, a third reviewer; the most experienced member (JM), provided a consensus through discussion.

Data collection process

Two independent researchers (GN and ND) extracted the data from the eligible trials. In case of disagreement, a third reviewer (JM), provided a consensus through discussion. Data extraction included the author, year, study population, sample size, age, intervention/comparison group, follow up periods, primary and secondary outcomes and the protocol for postoperative therapy. When insufficient data were presented, GN contacted the authors by email and requested further data.

Assessment of risk of bias in individual studies

Two independent review authors (GN and ND) assessed the trials for risk of bias. In case of disagreement, a third reviewer (JM), provided a consensus through discussion. The risk of bias assessment was performed using the Cochrane Risk of Bias tool [14]. The Cochrane Risk of Bias tool is based on 7 items, random sequence generation, allocation concealment, blinding of participants and personnel, blinding of outcome assessment, incomplete outcome data, selective reporting and other bias [14]. The other bias category was defined as trials that did not include statements on sources of funding and potential sources of conflicts of interest. We then rated the adequacy of each of the seven risk of bias domains as “low”, “unclear” or “high” risk according to criteria provided in the Cochrane Handbook for Systematic Reviews of Interventions [14]. (S1 Table).

Assessing the quality of evidence

We used the GRADE approach for systematic reviews, to assess the quality of evidence related to each outcome to summarize the extent of our confidence in the estimates of the effect[16–21]. The GRADE approach considers the risk of bias, publication bias, consistency of findings, precision, and the applicability of the overall body of literature to provide a rating of quality of evidence (high, moderate, low, or very low) per outcome [16–21].

Summary measures

To quantify and interpret our data, a minimally clinically important difference (MCID) of 1.4 points (0–10) for pain [22], a standard deviation of 0.5 points for function [23], 11.7 degrees for active shoulder forward flexion range of motion and 4.9 degrees for active shoulder external rotation range of motion were used [24] Timing of outcome assessment were categorised as 3 months, 6-months and 12-months only.

Subgroup analysis and exploring heterogeneity

In the presence of heterogeneity, we planned to perform the following subgroup analyses (a priori): trials at low risk of bias (low risk of bias in allocation concealment and blinding of outcome assessor if objective outcomes were used) would show a smaller effect size, size of the tendon tear and postoperative therapy received. An I2 estimate of at least 50% and a statistically significant Chi2 statistic (P = 0.10) was interpreted as evidence of a substantial problem with heterogeneity [25].

Synthesis of results

We performed 12 meta-analyses of trials comparing arthroscopic vs mini open repair, using the outcome function, whether reported by WORC, DASH or Constant; pain, reported by VAS; and range of motion, at 3-, 6- and 12-month follow ups. We used the Review Manager 5.3 (RevMan 5.3) software to conduct our review and a random-effects model to pool outcomes. For outcomes of the same construct (function) that were measured using a different metric, we used the standardized mean difference (SMD). If all eligible trials measured an outcome using the same metric (pain, flexion and external range of motion), we used a weighted mean difference (WMD).

Results

Study selection

Initially, our search yielded 705 publications. After removal of the duplicates, 437 articles remained and were screened using their title and abstract; leaving 11 articles selected for full text review. Of these, 6 RCTs were eligible [26–31]. The flow of studies through the selection process is presented in Fig 1.

Fig. 1. Selection of studies for inclusion in the systematic review.
Selection of studies for inclusion in the systematic review.

Study characteristics

The 6 eligible RCTs were conducted between 2011 and 2018 and included 670 patients (337 arthroscopic and 333 mini-open) [26–31]. Study size ranged from 34 to 274 patients. Trials were conducted in Japan, Germany, South Korea, Netherlands, China and Canada[26–31]. Only one out of the six trials were registered in a clinical trials register[29]. In addition, 50% of the trials (n = 3) did not include statements on sources of funding or potential sources of conflicts of interest [26,30–31]. A summary description of all the included RCTs is displayed in Table 1.

Tab. 1. Summary of included randomized controlled trials (RCTs) studies.
Summary of included randomized controlled trials (RCTs) studies.

Risk of bias assessment in the individual studies

The risk of bias assessment is presented in Fig 2. Performance bias (lack of or inadequate blinding of participants who could influence how interventions, including co-interventions are performed/administered) was rated at high risk in all the included trials (n = 6)[26–31] Detection bias (lack of or inadequate blinding of participants who could influence the measurement or interpretation of outcomes) and Selective Reporting bias were rated at high risk in five trials[26, 27, 28, 30–31]. Selection bias and attrition bias (significant or imbalanced missing outcome data) were rated at high risk in three [26,27,31], and four trials respectively [26, 28, 30–31]. Other biases (RCTs with no statements on sources of funding/conflicts of interest) were rated at high risk in two trials[26,30]. Overall, all six included RCTs were rated at high risk of bias[26–31].

Fig. 2. Risk of bias summary: Review authors’ judgements about each risk of bias item for each included study.
Risk of bias summary: Review authors’ judgements about each risk of bias item for each included study.

GRADE Evidence Profile (EP) and Summary of Findings (SoF)

The EP (Table 2) displays a detailed quality assessment and includes a judgment of each factor that determined the quality of evidence for each outcome. The SoF tables (Tables 3–5) include an assessment of the quality of evidence for each outcome.

Tab. 2. Grade evidence profile: Arthroscopic vs mini-open for patients with rotator cuff tears.
Grade evidence profile: Arthroscopic vs mini-open for patients with rotator cuff tears.
Tab. 3. Summary of findings.
Summary of findings.
Arthroscopic vs open-mini repair for rotator cuff tears (3-month).
Tab. 4. Summary of findings.
Summary of findings.
Arthroscopic vs open-mini repair for rotator cuff tears (6-month).
Tab. 5. Summary of findings.
Summary of findings.
Arthroscopic vs open-mini repair for rotator cuff tears (12-month).

Participants

Among the eligible RCTs, one recruited patients with an isolated rupture of the supraspinatus tendon (various degrees)[27], one included patients with rotator cuff tears smaller than 3 cm[26], two included patients with full-thickness rotator cuff tears[28,30], one recruited patients with partial and full thickness rotator cuff tears[31], and one included patients with small or medium rotator cuff tears[29].

Outcomes

Pain levels were measured using a Visual Analogue Scale (VAS)[26,27,28,30]. Function was measured using DASH[28,30], Constant[27,28,30] and WORC[29]. Range of motion, in degrees was assessed in all six trials[26–31]. The follow-up period was up to 41 months postoperatively.

Effects on function (patient reported function)

Four studies were pooled to examine the effects of arthroscopic vs mini-open on function at 3-month follow up. The pooled results, demonstrated no significant difference between arthroscopic and mini open approach to rotator cuff repair (very low quality, 4 RCTs, 495 patients, SMD 0.00, 95% CI: -0.18 to 0.18, p = 0.98, Fig 3). We found similar results at 6-month follow up, (very low quality, 4 RCTs, 495 patients, SMD -0.01, 95% CI: -0.23 to 0.21, p = 0.93, Fig 4) and at 12-month follow up, (very low quality, 3 RCTs, 462 patients, SMD -0.09, 95% CI: -0.28 to 0.09, p = 0.31, Fig 5). Heterogeneity was low at 3 and 6 months and absent at 12 months. Given that an MCID is approximately 0.5 SD[23], and that the 95% CIs at each follow up exclude the MCID of 0.5 SD, for majority of patients either approach to rotator cuff repair will result in superior functional outcomes (12 month arthroscopic mean function 66.7/100; mini-open mean function 68.3/100).

Fig. 3. Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: Function (DASH, Constant, WORC), 4 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: Function (DASH, Constant, WORC), 4 RCTs.
Higher values indicate better/improved function.
Fig. 4. Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: Function (DASH, Constant, WORC), 4 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: Function (DASH, Constant, WORC), 4 RCTs.
Higher values indicate better/improved function.
Fig. 5. Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: Function (DASH, WORC), 3 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: Function (DASH, WORC), 3 RCTs.
Higher values indicate better/improved function.

Effects on pain (patient reported pain)

Three studies were pooled to examine the effects of arthroscopic vs mini-open on pain levels at 3-month follow up. The pooled results, were not statistically different between groups (very low quality, 3 RCTs, 254 patients, MD -0.21, 95% CI: -0.91 to 0.50, p = 0.56, Fig 6). We found similar results at both 6- and 12-month follow ups, (very low quality, 3 RCTs, 254 patients, MD -0.03, 95% CI: -0.25 to 0.19, p = 0.80, Fig 7; very low quality, 2 RCTs, 194 patients, MD -0.35, 95% CI: -1.02 to 0.31, p = 0.30, Fig 8) respectively. Heterogeneity was absent for all analyses. Because the 95% CIs at each follow up exclude the MCID of 1.4 points on a 10-point scale[22], it is extremely unlikely that either approach to rotator cuff repair will result in lower pain levels.

Fig. 6. Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: Pain (VAS 0–10), 3 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: Pain (VAS 0–10), 3 RCTs.
Lower values indicate better/improved pain.
Fig. 7. Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: Pain (VAS 0–10), 3 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: Pain (VAS 0–10), 3 RCTs.
Lower values indicate better/improved pain.
Fig. 8. Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: Pain (VAS 0–10), 2 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: Pain (VAS 0–10), 2 RCTs.
Lower values indicate better/improved pain.

Effects on forward flexion range of motion (performance-based function)

Five studies were pooled to examine the effects of arthroscopic vs mini-open on shoulder forward flexion range of motion at 3-month follow up. The pooled results, showed no statistically significant difference between groups (very low quality, 5 RCTs, 555 patients, MD 4.26, 95% CI: -0.56 to 9.09, p = 0.08, Fig 9). Our findings were similar at both the 6- and 12-month follow ups, (very low quality, 5 RCTs, 555 patients, MD 1.39, 95% CI: -2.12 to 4.90, p = 0.44, Fig 10; very low quality, 3 RCTs, 461 patients, MD 2.94, 95% CI: -4.55 to 10.44, p = 0.44, Fig 11) respectively. Heterogeneity was absent in the analysis of 3 and 6 month follow up, and because the 95% CIs exclude the MCID of 11.7°[24], it is extremely unlikely that either approach to rotator cuff repair will result in better flexion range of motion. Heterogeneity was substantial in the analysis of 12 month follow up and our subgroup analysis of the two studies at high risk of detection bias indicated that the likely cause of substantial heterogeneity was due to inadequate blinding of outcome assessors. The one remaining MacDermid et al. (2018) study with adequate blinding of outcome assessors showed no statistically significant difference between groups (1 RCT, 267 patients, MD -0.90, 95% CI: -5.34 to 3.54, p = 0.69) and because the 95% CIs exclude the MCID of 11.7 degrees[24], it is unlikely that either approach to rotator cuff repair will result in better flexion range of motion.

Fig. 9. Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: ROM (Forward Flexion°), 5 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: ROM (Forward Flexion°), 5 RCTs.
Higher values indicate better/improved ROM.
Fig. 10. Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: ROM (Forward Flexion°), 5 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: ROM (Forward Flexion°), 5 RCTs.
Higher values indicate better/improved ROM.
Fig. 11. Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: ROM (Forward Flexion°), 3 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: ROM (Forward Flexion°), 3 RCTs.
1.1.2 Subgroup analysis by high risk of detection bias, 2 RCTs. Higher values indicate better/improved ROM.

Effects on external rotation range of motion (performance-based function)

Five studies were pooled to examine the effects of arthroscopic vs mini-open on shoulder external rotation range of motion at 3-month follow up. The pooled results, showed no statistically significant difference between groups (very low quality, 4 RCTs, 522 patients, MD 1.13, 95% CI: -2.08 to 4.33, p = 0.49, Fig 12). Our findings were similar at the 6-month follow up (very low quality, 4 RCTs, 522 patients, MD 0.12, 95% CI: -2.82 to 3.06, p = 0.94, Fig 13). However, at 12-month follow up the pooled results showed statistically significant difference between groups (very low quality, 3 RCTs, 462 patients, MD 3.71, 95% CI: 0.14 to 7.28, p = 0.04, Fig 14). Heterogeneity was absent in the analysis of 3 and 6 month follow up and low at 12 months. Given the MCID of 4.9 degrees[24], we can confidently rule out the possibility that surgical approach will cause a difference in external rotation range of motion at 6 months. However, we are unable to make this same declaration for the results at 3 and 12 months as it remains possible that an arthroscopic approach could offer superior outcomes in terms of external rotation range of motion. More data is required to make a definitive conclusion.

Fig. 12. Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: ROM (External Rotation°), 5 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 3 months after surgery–rotator cuff repair, outcome: ROM (External Rotation°), 5 RCTs.
Higher values indicate better/improved ROM.
Fig. 13. Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: ROM (External Rotation°), 4 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 6 months after surgery–rotator cuff repair, outcome: ROM (External Rotation°), 4 RCTs.
Higher values indicate better/improved ROM.
Fig. 14. Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: ROM (External Rotation°), 3 RCTs.
Forest plot of comparison: Arthroscopic vs Open-mini, 12 months after surgery–rotator cuff repair, outcome: ROM (External Rotation°), 3 RCTs.
Higher values indicate better/improved ROM.

Discussions

We aimed to summarise the current evidence of the effects of arthroscopic vs mini-open rotator cuff repair on clinical outcomes. Our forest plots for flexion and external rotation range of motion outcomes displayed that when considering the results of individual studies (not pooled analyses), there is a trend, indicating that arthroscopic treatment may yield better outcomes. However, upon meta-analysis, we found no clinically important differences in function, pain, flexion or external rotation range of motion at 3-, 6- or 12-month follow ups.

Quality of the evidence

The rating of very low-quality evidence per outcome across trials was based on the judgement of serious limitations (risk of bias), serious imprecision and likely publication bias in all the outcomes across trials. All six trials identified in this review were rated at high risk of bias. However, we downgraded the evidence only by one level due to the fact that we did not find statistical differences between groups, suggesting that the included studies may not have been biased. Furthermore, serious indirectness was judged as an additional factor in rating down the quality of evidence for half the outcomes across trials. The very low-quality evidence synthesised limits our confidence in the effect estimates. However, given that MCID thresholds for function, pain and range of motions, as well as the 95% CI excluding these thresholds, it is unlikely that either approach to rotator cuff repair will result in superior clinical outcomes.

Agreements / Disagreements with other reviews

The results of our systematic review and meta-analysis could not directly be compared to the findings of Shan et al. (2014), Huang et al. (2016) or Ji et al. (2015) reviews[2–4]. The Shan et al. (2014) review of 12 studies (3 RCTs, 8 retrospective studies, 1 prospective study) concluded that there were no differences in clinical outcomes of pain, function and range of motion between the arthroscopic and mini-open rotator cuff repair approaches[4]. The Huang et al. (2016) review of 18 studies (4 RCTs, 12 retrospective studies, 2 prospective study) indicated that all-arthroscopic and mini-open rotator cuff repair surgical approaches are associated with similar clinical outcomes of function, pain and range of motion and that both surgical techniques can be used interchangeably based factors such as patient and rotator tear characteristics[2]. However, it is important to note that the aforementioned reviews pooled studies to provide effect estimates irrespective of their design; RCTs were combined with prospective and retrospective observational studies. This greatly limits our confidence in the effect estimates [2,4]. Furthermore, the reviews failed to define an MCID threshold a priori, to further support their well-conducted meta-analyses and ultimately their conclusions. The Ji et al. (2015) review included 5 RCTs and concluded that there were no differences in clinical outcomes between the arthroscopic and mini-open rotator cuff repair techniques[3]. However, it is important to highlight the fact that this review pooled RCTs based on the last follow-up time point reported, which ranged from 6-months to 34-months. It is likely that the underlying reason for the high levels of heterogeneity identified in the Ji et al. (2015) review were due to the pooling of trials with such wide range of follow-ups. In addition, the review did not provide ratings of the quality of evidence and similarly failed to define an MCID threshold a priori to further support their conclusions.

Our review provides the most up-to-date state of the evidence concerning the clinical outcomes of arthroscopic vs mini-open rotator cuff repair techniques. We provided ratings of the quality of evidence according to GRADE guidelines across each outcome, included two additional large trials and provided an analysis of precision by evaluating the MCID thresholds with the 95% confidence intervals, therefore, able to make definitive conclusions for most of the included clinical outcomes. We could not provide definitive statements on whether arthroscopic approach could offer superior outcomes in terms of external rotation range of motion at 3 and 12 months because our analysis of 555 and 462 patients respectively, did not meet the criteria for our calculated Optimal Information Size of 754. As a result, it produced wider confidence intervals, therefore, MCID threshold not excluded. (S1 Fig)

Hui et al. 2017 study of 226 patients compared the immediate costs associated in patients who received mini-open and arthroscopic rotator cuff repairs and indicated that immediate costs incurred by mini-open rotator cuff technique were significantly less than those of arthroscopic technique. However, it is important to note that this was a retrospective study, and outcomes were only analysed only at 1 year follow up[32].

Implications for research

We have limited confidence in our conclusions. Future well-designed large-scale RCTs investigating the effects of arthroscopic vs mini-open rotator cuff repair techniques on clinical outcomes of function, pain and range of motion are warranted to generate high quality evidence (i.e. greater confidence) to further ensure that the true effect lies close to that of the estimate of the effect. In addition, future cost-effectiveness trials comparing the two surgical technique are warranted.

Implications for practice

Both arthroscopic and mini-open approaches to rotator cuff repair with post-operative rehabilitation are effective means of improving function, pain and shoulder range of motion in patients with rotator cuff tears. Despite the very-low quality synthesized, we continue to suggest that the difference between the two surgical techniques are too small to be clinically important in terms of improving clinical outcomes of function, pain and range of motion.

Strengths & limitations

We were mainly concerned with identifying RCTs and therefore, did not included prospective or retrospective observational studies in this review. It is possible that there might be a source of publication bias within our search strategy. Two independent reviewers conducted the electronic searches in all the major databases. Furthermore, a protocol registration was undertaken prior to the conduct of this review.

Conclusions

The effects of arthroscopic compared to mini-open rotator cuff repair, on function, pain and range of motion are too small to be clinically important at 3-, 6- and 12-month follow ups.

Supporting information

S1 PRISMA Checklist [pdf]

S1 Table [pdf]

S1 Fig [pdf]

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Článek Framework for rational donor selection in fecal microbiota transplant clinical trials
Článek HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy
Článek Health assessment of Conolophus subcristatus, Conolophus pallidus, and C. subcristatus X Amblyrhynchus cristatus hybrid (Galápagos land iguanas)
Článek Prognostic value of post-induction chemotherapy 18F-FDG PET-CT in stage II/III non-small cell lung cancer before (chemo-) radiation
Článek Risk factor-based subphenotyping of heart failure in the community
Článek An efficient and adaptive data-hiding scheme based on secure random matrix
Článek Endovascular treatment of different types of iliac occlusions—Results from an observational study
Článek Variation in pickleweed root-associated microbial communities at different locations of a saline solid waste management unit contaminated with petroleum hydrocarbons
Článek Consumption of rice, acceptability and sensory qualities of fortified rice amongst consumers of social safety net rice in Nepal
Článek Quantitative analysis of the bilateral coordination and gait asymmetry using inertial measurement unit-based gait analysis
Článek Application of metagenomic shotgun sequencing to detect vector-borne pathogens in clinical blood samples
Článek Higher underestimation of tumour size post-neoadjuvant chemotherapy with breast magnetic resonance imaging (MRI)—A concordance comparison cohort analysis
Článek Wealth accumulation in rotation forestry – Failure of the net present value optimization?
Článek Increased incidence of age-related macular degeneration in sensorineural hearing loss: A population-based cohort study
Článek Evaluating the foundations that help avert antimicrobial resistance: Performance of essential water sanitation and hygiene functions in hospitals and requirements for action in Kenya
Článek Effects of a hot ambient operating theatre on manual dexterity, psychological and physiological parameters in staff during a simulated burn surgery
Článek Introduction of quality management in a National Reference Laboratory in Germany
Článek Histopathological investigation of complex gill disease in sea farmed Atlantic salmon
Článek Common variants in glyoxalase I do not increase chronic pancreatitis risk
Článek Cognitive impairment in multiple sclerosis: An exploratory analysis of environmental and lifestyle risk factors
Článek Japanese nationwide survey of hypophosphatasia reveals prominent differences in genetic and dental findings between odonto and non-odonto types
Článek Interaction of detergents with biological membranes: Comparison of fluorescence assays with filtration protocols and implications for the rates of detergent association, dissociation and flip-flop
Článek Potential causes of early death among admitted newborns in a rural Tanzanian hospital
Článek Identification of glomerular and podocyte-specific genes and pathways activated by sera of patients with focal segmental glomerulosclerosis
Článek Prevalence and correlates of partner violence among adolescent girls and young women: Evidence from baseline data of a cluster randomised trial in Tanzania
Článek Development of an integrated fingerstick blood self-collection device for radiation countermeasures
Článek Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease
Článek Broiler welfare trade-off: A semi-quantitative welfare assessment for optimised welfare improvement based on an expert survey
Článek Engagement in care among women and their infants lost to follow-up under Option B+ in eSwatini
Článek Hyperglycemia in the early stages of type 1 diabetes accelerates gastric emptying through increased networks of interstitial cells of Cajal
Článek Nanoaperture fabrication via colloidal lithography for single molecule fluorescence analysis
Článek A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis
Článek Sialochemical analysis in polytraumatized patients in intensive care units
Článek The black sheep effect: The case of the deviant ingroup robot
Článek No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer’s disease
Článek Implementation of an international standardized set of outcome indicators in pregnancy and childbirth in Kenya: Utilizing mobile technology to collect patient-reported outcomes
Článek Breastfeeding support through wet nursing during nutritional emergency: A cross sectional study from Rohingya refugee camps in Bangladesh
Článek Does route matter? Impact of route of oxytocin administration on postpartum bleeding: A double-blind, randomized controlled trial
Článek Research on OpenCL optimization for FPGA deep learning application
Článek Drug therapy problems, medication adherence and treatment satisfaction among diabetic patients on follow-up care at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
Článek Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
Článek The dynamics of Early Celtic consumption practices: A case study of the pottery from the Heuneburg
Článek Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial
Článek “Cementing” marriages through childbearing in subsequent unions: Insights into fertility differentials among first-time married and remarried women in Ghana
Článek Single session high definition transcranial direct current stimulation to the cerebellum does not impact higher cognitive function
Článek The contribution of age structure to the international homicide decline
Článek Genetic structure of Mexican lionfish populations in the southwest Gulf of Mexico and the Caribbean Sea
Článek A physiological dose of oral vitamin B-12 improves hematological, biochemical-metabolic indices and peripheral nerve function in B-12 deficient Indian adolescent women
Článek Nutritional status, cognitive achievement, and educational attainment of children aged 8-11 in rural South India
Článek Costs and cost-effectiveness analyses of mCARE strategies for promoting care seeking of maternal and newborn health services in rural Bangladesh
Článek Cause-specific mortality in the general population with transient dipstick-proteinuria
Článek Assessing hand dysfunction in cervical spondylotic myelopathy
Článek KETOS: Clinical decision support and machine learning as a service – A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services
Článek Variation in activity rates may explain sex-specific dorsal color patterns in Habronattus jumping spiders
Článek Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka
Článek Acute sprint exercise transcriptome in human skeletal muscle
Článek Parenting and personality disorder: An overview and meta-synthesis of systematic reviews
Článek Female rats release a trapped cagemate following shaping of the door opening response: Opening latency when the restrainer was baited with food, was empty, or contained a cagemate
Článek Multiplex communities and the emergence of international conflict
Článek The impact of socioeconomic status on emergency department outcome in a low-income country setting: A registry-based analysis
Článek Effect of psycho-social support by teachers on improving mental health and hope of adolescents in an earthquake-affected district in Nepal: A cluster randomized controlled trial
Článek A cluster-randomized controlled trial of the effectiveness of the JUMP Math program of math instruction for improving elementary math achievement
Článek Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1
Článek Use of rapid Model for End-Stage Liver Disease (MELD) increases for liver transplant registrant prioritization after MELD-Na and Share 35, an evaluation using data from the United Network for Organ Sharing
Článek Fishery Improvement Projects as a governance tool for fisheries sustainability: A global comparative analysis
Článek QRStree: A prefix tree-based model to fetal QRS complexes detection
Článek Fundraising and vote distribution: A non-equilibrium statistical approach
Článek Evaluation of PRRSv specific, maternally derived and induced immune response in Ingelvac PRRSFLEX EU vaccinated piglets in the presence of maternally transferred immunity
Článek Gene expression profiling of whole blood: A comparative assessment of RNA-stabilizing collection methods
Článek Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation
Článek Isoniazid preventive therapy: Uptake, incidence of tuberculosis and survival among people living with HIV in Bulawayo, Zimbabwe
Článek P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib
Článek Using long-term datasets to assess the impacts of dietary exposure to neonicotinoids on farmland bird populations in England
Článek Genetic mapping of distal femoral, stifle, and tibial radiographic morphology in dogs with cranial cruciate ligament disease
Článek Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors
Článek Consumer beliefs about healthy foods and diets
Článek An observational study on intracutaneous sodium storage in intensive care patients and controls
Článek Recovery when you are on your own: Slow population responses in an isolated marine reserve
Článek How does the method change what we measure? Comparing virtual reality and text-based surveys for the assessment of moral decisions in traffic dilemmas
Článek Is recent Afghanistan survey data suitable for fertility analysis? A regional investigation based on fertility inhibiting determinants
Článek Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations
Článek Comparison of two swept-source optical coherence tomography biometers and a partial coherence interferometer
Článek Removal of anthracycline cytostatics from aquatic environment: Comparison of nanocrystalline titanium dioxide and decontamination agents
Článek A social media intervention to improve nutrition knowledge and behaviors of low income, pregnant adolescents and adult women
Článek Detection of vision and /or hearing loss using the interRAI Community Health Assessment aligns well with common behavioral vision/hearing measurements
Článek E-MOVIE - Experimental MOVies for Induction of Emotions in neuroscience: An innovative film database with normative data and sex differences
Článek Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK Biobank
Článek An elevated glycemic gap predicts adverse outcomes in diabetic patients with necrotizing fasciitis
Článek 40-Hz auditory steady-state responses and the complex information processing: An exploratory study in healthy young males
Článek Highly diverse anaerobe-predominant vaginal microbiota among HIV-infected pregnant women in Zambia
Článek Decision-based models of the implementation of interventions in systems of healthcare: Implementation outcomes and intervention effectiveness in complex service environments
Článek Dual number-based variational data assimilation: Constructing exact tangent linear and adjoint code from nonlinear model evaluations
Článek Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
Článek Use of IoT sensing and occupant surveys for determining the resilience of buildings to forest fire generated PM2.5
Článek Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis
Článek Lek-associated movement of a putative Ebolavirus reservoir, the hammer-headed fruit bat (Hypsignathus monstrosus), in northern Republic of Congo
Článek Attenuation correction using 3D deep convolutional neural network for brain 18F-FDG PET/MR: Comparison with Atlas, ZTE and CT based attenuation correction
Článek Differences in macular capillary parameters between healthy black and white subjects with Optical Coherence Tomography Angiography (OCTA)
Článek Sealing agent reduces formation of single and dual-species biofilms of Candida albicans and Enterococcus faecalis on screw joints at the abutment/implant interface
Článek Chitotetraose activates the fungal-dependent endosymbiotic signaling pathway in actinorhizal plant species
Článek What is the optimum time for initiation of early mobilization in mechanically ventilated patients? A network meta-analysis
Článek Cognitive aptitude, peers, and trajectories of marijuana use from adolescence through young adulthood
Článek Early mortality after diagnosis of cancer of the head and neck – A population-based nationwide study
Článek Accuracy and interobserver-agreement of respiratory rate measurements by healthcare professionals, and its effect on the outcomes of clinical prediction/diagnostic rules
Článek Does task delegation to non-physician health professionals improve quality of diabetes care? Results of a scoping review
Článek The Univariate Flagging Algorithm (UFA): An interpretable approach for predictive modeling
Článek Profiles and trajectories of impaired social cognition in people with Prader-Willi syndrome
Článek Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly
Článek Sub-types of safety behaviours and their effects on social anxiety disorder
Článek Engaging in prosocial behavior explains how high self-control relates to more life satisfaction: Evidence from three Chinese samples
Článek Artificial fingerprints for cross-comparison of forensic DNA and protein recovery methods
Článek The organization of Golgi in Drosophila bristles requires microtubule motor protein function and a properly organized microtubule array
Článek Direct and moderating effects of environmental regulation intensity on enterprise technological innovation: The case of China
Článek Prevalence and associated factors of depression among Korean adolescents
Článek Transcriptome analysis of PK-15 cells in innate immune response to porcine deltacoronavirus infection
Článek Geographic variation in cardiometabolic risk distribution: A cross-sectional study of 256,525 adult residents in the Illawarra-Shoalhaven region of the NSW, Australia
Článek Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury
Článek Lipid profile changings after switching from rilpivirine/tenofovir disoproxil fumarate/emtricitabine to rilpivirine/tenofovir alafenamide/emtricitabine: Different effects in patients with or without baseline hypercholesterolemia
Článek A feature selection strategy for gene expression time series experiments with hidden Markov models
Článek Dissociating the sequential dependency of subjective temporal order from subjective simultaneity
Článek Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis
Článek Population-based estimates of engagement in HIV care and mortality using double-sampling methods following home-based counseling and testing in western Kenya
Článek Vaginal temperature as indicative of thermoregulatory response in Nellore heifers under different microclimatic conditions
Článek Galectin-9 gene (LGALS9) polymorphisms are associated with rheumatoid arthritis in Brazilian patients
Článek The association of brightness with number/duration in human newborns
Článek Microslit on a chip: A simplified filter to capture circulating tumor cells enlarged with microbeads
Článek Integrating continuous differential evolution with discrete local search for meander line RFID antenna design
Článek The impact of the French soda tax on prices and purchases. An ex post evaluation
Článek Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications
Článek Structural characterization of a novel polysaccharide from Sargassum thunbergii and its antioxidant and anti-inflammation effects
Článek Potential biomarker identification for Friedreich’s ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion
Článek Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil
Článek Chile (Capsicum annuum) plants transformed with the RB gene from Solanum bulbocastanum are resistant to Phytophthora capsici
Článek Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
Článek Analysis of gene co-expression networks of phosphate starvation and aluminium toxicity responses in Populus spp.
Článek Risk factors associated with IgA vasculitis with nephritis (Henoch–Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis
Článek The prediction model of suicidal thoughts in Korean adults using Decision Tree Analysis: A nationwide cross-sectional study
Článek A multidimensional understanding of prosperity and well-being at country level: Data-driven explorations
Článek Factors associated with muscle mass in community-dwelling older people in Singapore: Findings from the SHIELD study
Článek The prevalence and risk of non-infectious comorbidities in HIV-infected and non-HIV infected men attending general practice in Australia
Článek Vibrio cholerae strains with inactivated cqsS gene overproduce autoinducer-2 which enhances resuscitation of dormant environmental V. cholerae
Článek Myocardial function in patients with anomalous left coronary artery from the pulmonary artery syndrome: A long-term speckle tracking echocardiographic study
Článek Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo
Článek Joint distribution for number of crossings and longest run in independent Bernoulli observations. The R package crossrun
Článek Learning to play badminton altered resting-state activity and functional connectivity of the cerebellar sub-regions in adults
Článek Children’s dietary diversity and related factors in Rwanda and Burundi: A multilevel analysis using 2010 Demographic and Health Surveys
Článek Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease
Článek Precluding rare outcomes by predicting their absence
Článek Tidal inlet seafloor changes induced by recently built hard structures
Článek A further study on Franciscobasis Machado & Bedê, 2016 (Odonata: Coenagrionidae), a newly described genus from Minas Gerais, Brazil
Článek Associative responses to visual shape stimuli in the mouse auditory cortex
Článek Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models
Článek LRP receptors in chondrocytes are modulated by simulated microgravity and cyclic hydrostatic pressure
Článek Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases
Článek Separating the effects of temperature and carbon allocation on the diel pattern of soil respiration in the different phenological stages in dry grasslands
Článek Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks – Peaks, growths, and foresight in swine production
Článek Factors associated with exclusive breast-feeding: A cross-sectional survey in Kaiyuan, Yunnan, Southwest China
Článek The Model of Mortality with Incident Cirrhosis (MoMIC) and the model of Long-term Outlook of Mortality in Cirrhosis (LOMiC)
Článek Burden of treatment-resistant depression in Medicare: A retrospective claims database analysis
Článek Genomic characterisation of perinatal Western Australian Streptococcus agalactiae isolates
Článek Sharing the filmic experience - The physiology of socio-emotional processes in the cinema
Článek A super-SILAC based proteomics analysis of diffuse large B-cell lymphoma-NOS patient samples to identify new proteins that discriminate GCB and non-GCB lymphomas
Článek Pneumoproteins are associated with pulmonary function in HIV-infected persons
Článek Tissue-specific expression of IgG receptors by human macrophages ex vivo
Článek Electrical impedance myography for the detection of muscle inflammation induced by λ-carrageenan
Článek Clustering of the structures by using “snakes-&-dragons” approach, or correlation matrix as a signal
Článek Asymmetric valuation of gains and losses in effort-based decision making
Článek Genomic and metabolic differences between Pseudomonas putida populations inhabiting sugarcane rhizosphere or bulk soil
Článek Method comparison for N-glycan profiling: Towards the standardization of glycoanalytical technologies for cell line analysis
Článek Gender linked fate explains lower legal abortion support among white married women
Článek L-3,3’,5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors
Článek eQTL mapping of rare variant associations using RNA-seq data: An evaluation of approaches
Článek Cell fishing: A similarity based approach and machine learning strategy for multiple cell lines-compound sensitivity prediction
Článek Macrogeographic genetic structure of Lutzomyia longipalpis complex populations using Next Generation Sequencing
Článek Dual-career through the elite university student-athletes’ lenses: The international FISU-EAS survey
Článek Machine learning prediction of emesis and gastrointestinal state in ferrets
Článek Impact of bitter tastant sub-qualities on retronasal coffee aroma perception
Článek Head orientation and electrode placement potentially influence fetal scalp ECG waveform
Článek Clinical outcomes associated with the use of the NexSite hemodialysis catheter with new exit barrier technology: Results from a prospective, observational multi-center registry study
Článek Geospatial correlates of early marriage and union formation in Ghana
Článek Disruption of white matter connectivity in chronic obstructive pulmonary disease
Článek Integrated evaluation of clinical, pathological and radiological prognostic factors in squamous cell carcinoma of the lung
Článek Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1
Článek Pyk2-dependent phosphorylation of LSR enhances localization of LSR and tricellulin at tricellular tight junctions
Článek An alternative approach for estimating the number needed to treat for survival endpoints
Článek Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
Článek Can telemedicine initiative be an effective intervention strategy for improving treatment compliance for pediatric HIV patients: Evidences on costs and improvement in treatment compliance from Maharashtra, India
Článek Trial registration as a safeguard against outcome reporting bias and spin? A case study of randomized controlled trials of acupuncture
Článek Multi-disciplinary interventions for chronic pain involving education: A systematic review
Článek Impact of climate change on the integrity of the superstructure of deteriorated U.S. bridges
Článek Switching to bedaquiline for treatment of rifampicin-resistant tuberculosis in South Africa: A retrospective cohort analysis
Článek Efficacy of Lactobacillus-supplemented triple therapy for H. pylori eradication: A meta-analysis of randomized controlled trials
Článek Testing gene by community disadvantage moderation of sexual health outcomes among urban women
Článek The impact of leishmaniasis on mental health and psychosocial well-being: A systematic review
Článek Evaluation of a screening algorithm using the Strengths and Difficulties Questionnaire to identify children with mental health problems: A five-year register-based follow-up on school performance and healthcare use
Článek Optimized fast GPU implementation of robust artificial-neural-networks for k-space interpolation (RAKI) reconstruction
Článek The cost of illness and economic burden of endometriosis and chronic pelvic pain in Australia: A national online survey
Článek Refined distributed emotion vector representation for social media sentiment analysis
Článek Enhancing timeliness of drug overdose mortality surveillance: A machine learning approach
Článek A real-time gesture recognition system using near-infrared imagery
Článek Alcohol use and its association with sexual risk behaviors in the Armed Forces of the Republic of the Congo
Článek Improved survival rates in patients with H1N1 acute respiratory failure in Korea between 2009 and 2016
Článek Electroencephalographic features of discontinuous activity in anesthetized infants and children
Článek Tumor stromal type is associated with stromal PD-L1 expression and predicts outcomes in breast cancer
Článek Mutant prevention concentration of ozenoxacin for quinolone-susceptible or -resistant Staphylococcus aureus and Staphylococcus epidermidis
Článek The Echobot: An automated system for stimulus presentation in studies of human echolocation
Článek Evaluation of clinical manifestations, health risks, and quality of life among women with polycystic ovary syndrome
Článek Magnetic resonance imaging presentation of deep infiltrating endometriosis nodules before and after pregnancy: A case series
Článek Agrobacterium tumefaciens-mediated transformation of a hevein-like gene into asparagus leads to stem wilt resistance
Článek Effect of a Mentor Mother Programme on retention of mother-baby pairs in HIV care: A secondary analysis of programme data in Uganda
Článek Utilizing multiplex fluor LAMPs to illuminate multiple gene expressions in situ
Článek Genetic relationships between the RACK1 homolog cpc-2 and heterotrimeric G protein subunit genes in Neurospora crassa
Článek Is latent tuberculosis infection challenging in Iranian health care workers? A systematic review and meta-analysis
Článek A comparison of the risk of congestive heart failure-related hospitalizations in patients receiving hemodialysis and peritoneal dialysis - A retrospective propensity score-matched study
Článek A tailored approach to fusion transcript identification increases diagnosis of rare inherited disease
Článek Experiences, needs, and preferences for follow-up after stroke perceived by people with stroke and healthcare professionals: A focus group study
Článek Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: A randomized trial
Článek The Nordic Maintenance Care Program: Does psychological profile modify the treatment effect of a preventive manual therapy intervention? A secondary analysis of a pragmatic randomized controlled trial
Článek Within-subject variability in human retinal nerve fiber bundle width
Článek Motivation for alcohol consumption or abstinence during pregnancy: A clinical-qualitative study in Brazil
Článek Comparison of conventional BLUP and single-step genomic BLUP evaluations for yearling weight and carcass traits in Hanwoo beef cattle using single trait and multi-trait models
Článek Do cognitive and non-cognitive abilities mediate the relationship between air pollution exposure and mental health?
Článek Molecular phylogeny and morphology reveal a new epiphytic species of Habenaria (Orchidaceae; Orchideae; Orchidinae) from Nepal
Článek Nitrogen nutrition is a key modulator of the sugar and organic acid content in citrus fruit
Článek Understanding variation in health service coverage and maternal health outcomes among districts in Rwanda – A qualitative study of local health workers’ perceptions
Článek Biased cognition in East Asian and Western cultures
Článek Physical fitness and physical self-concept of male and female young adults in Qatar
Článek Robust policy evaluation from large-scale observational studies
Článek Improved semi-supervised autoencoder for deception detection
Článek Delineation of high resolution climate regions over the Korean Peninsula using machine learning approaches
Článek Are spasticity, weakness, selectivity, and passive range of motion related to gait deviations in children with spastic cerebral palsy? A statistical parametric mapping study
Článek ProphET, prophage estimation tool: A stand-alone prophage sequence prediction tool with self-updating reference database
Článek Conspicuous and cryptic reef fishes from a unique and economically important region in the northern Red Sea
Článek Time scale of resilience loss: Implications for managing critical transitions in water quality
Článek Effectiveness of physical and cognitive-behavioural intervention programmes for chronic musculoskeletal pain in adults: A systematic review and meta-analysis of randomised controlled trials
Článek Relationship between feed efficiency indexes and performance, body measurements, digestibility, energy partitioning, and nitrogen partitioning in pre-weaning dairy heifers
Článek Long-stay patients in pediatric intensive care unit: Diagnostic-specific definition and predictors
Článek Evidence of ritual breakage of a ground stone tool at the Late Natufian site of Hilazon Tachtit cave (12,000 years ago)
Článek Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease
Článek A systematic review and thematic synthesis of Canada’s LGBTQ2S+ employment, labour market and earnings literature
Článek The occurrence of ‘Sleeping Beauty’ publications in medical research: Their scientific impact and technological relevance
Článek Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii
Článek Assessing undergraduate student and faculty views on animal research: What do they know, whom do they trust, and how much do they care?
Článek The views and experiences of general dental practitioners (GDP’s) in West Yorkshire who used the International Caries Detection and Assessment System (ICDAS) in research
Článek Compare HIV/syphilis infections between age groups and explore associated factors of HIV/syphilis co-infections among men who have sex with men in Shenzhen, China, from 2009 to 2017
Článek Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
Článek Effect of exclusive breastfeeding cessation time on childhood morbidity and adverse nutritional outcomes in Ethiopia: Analysis of the demographic and health surveys
Článek Dual antiplatelet therapy in patients with cirrhosis and acute myocardial infarction – A 13-year nationwide cohort study
Článek Relationships between electrolyte and amino acid compositions in sweat during exercise suggest a role for amino acids and K+ in reabsorption of Na+ and Cl- from sweat
Článek A simplified vocal tract model for articulation of [s]: The effect of tongue tip elevation on [s]
Článek Management and glycemic control of patients with type 2 diabetes mellitus at primary care level in Kedah, Malaysia: A statewide evaluation
Článek Anabolic steroids among resistance training practitioners
Článek Factors associated with unsafe abortion practices in Nepal: Pooled analysis of the 2011 and 2016 Nepal Demographic and Health Surveys
Článek New methods of removing debris and high-throughput counting of cyst nematode eggs extracted from field soil
Článek Vehicle configurations associated with anatomical-specific severe injuries resulting from traffic collisions
Článek What has reproductive health decision-making capacity got to do with unintended pregnancy? Evidence from the 2014 Ghana Demographic and Health Survey
Článek Circulating levels of CD34+ cells predict long-term cardiovascular outcomes in patients on maintenance hemodialysis
Článek Penetration of linezolid into bone tissue 24 h after administration in patients with multidrug-resistant spinal tuberculosis
Článek Prosthesis design of animal models of periprosthetic joint infection following total knee arthroplasty: A systematic review
Článek Coherent diversification in corporate technological portfolios
Článek Technology opportunity discovery by structuring user needs based on natural language processing and machine learning
Článek Effect of tranexamic acid administration on acute traumatic coagulopathy in rats with polytrauma and hemorrhage
Článek Factors associated with the use of diet and the use of exercise for prostate cancer by long-term survivors
Článek Congenital Zika Syndrome in a Brazil-Paraguay-Bolivia border region: Clinical features of cases diagnosed between 2015 and 2018
Článek Trends and impact of antimicrobial resistance on older inpatients with urinary tract infections (UTIs): A national retrospective observational study
Článek Malawian children with uncomplicated and cerebral malaria have decreased activated Vγ9Vδ2 γδ T cells which increase in convalescence
Článek Predictors of mortality within the first year of initiating antiretroviral therapy in urban and rural Kenya: A prospective cohort study
Článek The investment case as a mechanism for addressing the NCD burden: Evaluating the NCD institutional context in Jamaica, and the return on investment of select interventions
Článek Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection
Článek Bringing fear into focus: The intersections of HIV and masculine gender norms in Côte d’Ivoire
Článek Scientific output scales with resources. A comparison of US and European universities
Článek Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis
Článek Effect of host genotype and Eimeria acervulina infection on the metabolome of meat-type chickens
Článek Gravity influences bevacizumab distribution in an undisturbed balanced salt solution in vitro
Článek Agrobacterium tumefaciens-mediated transformation and expression of GFP in Ascochyta lentis to characterize ascochyta blight disease progression in lentil
Článek Proteomic changes of aryl hydrocarbon receptor (AhR)-silenced porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Článek Localization and dynamic change of saponins in Cyclocarya paliurus (Batal.) Iljinskaja
Článek Improving the forecasting performance of temporal hierarchies
Článek Prevalence of surgically correctable conditions among children in a mixed urban-rural community in Nigeria using the SOSAS survey tool: Implications for paediatric surgical capacity-building
Článek Relatives’ attachment anxiety mediates the association between perceived loss and expressed emotion in early psychosis
Článek The impact of PEPFAR transition on HIV service delivery at health facilities in Uganda
Článek Impact of peri-intraventricular haemorrhage and periventricular leukomalacia in the neurodevelopment of preterms: A systematic review and meta-analysis
Článek Correction: Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis
Článek Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection
Článek Determination of factors affecting medication adherence in type 2 diabetes mellitus patients using a nationwide claim-based database in Japan
Článek Beyond the metabolic syndrome: Visceral and marrow adipose tissues impair bone quantity and quality in Cushing’s disease
Článek Clade II Candida auris possess genomic structural variations related to an ancestral strain
Článek Effect of aging on the association between ankle muscle strength and the control of bipedal stance
Článek Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model
Článek Kinematic and electromyographic analysis of variations in Nordic hamstring exercise
Článek Comparison of transcriptomes of an orthotospovirus vector and non-vector thrips species
Článek Trabeculectomy followed by phacoemulsification versus trabeculectomy alone: The Collaborative Bleb-Related Infection Incidence and Treatment Study
Článek Whole genome resequencing of watermelons to identify single nucleotide polymorphisms related to flesh color and lycopene content
Článek Religious practices and long-term survival after hospital discharge for an acute coronary syndrome
Článek Behavioral recovery and spinal motoneuron remodeling after polyethylene glycol fusion repair of singly cut and ablated sciatic nerves
Článek Platelets modulate multiple markers of neutrophil function in response to in vitro Toll-like receptor stimulation
Článek Comparative characterization of bacterial communities in geese consuming of different proportions of ryegrass
Článek Temperature sensitivity patterns of carbon and nitrogen processes in decomposition of boreal organic soils – Quantification in different compounds and molecule sizes based on a multifactorial experiment
Článek Cows painted with zebra-like striping can avoid biting fly attack
Článek The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model
Článek The accumulation of deficits approach to describe frailty
Článek Botulinum toxin A injection into the entopeduncular nucleus improves dynamic locomotory parameters in hemiparkinsonian rats
Článek Turing complete neural computation based on synaptic plasticity
Článek Influence of mydriasis on optical coherence tomography angiography imaging in patients with age-related macular degeneration
Článek Specialized care improves outcomes for patients with cirrhosis who require general surgical operations
Článek Association between plural legal systems and sexual and reproductive health outcomes for women and girls in Nigeria: A state-level ecological study
Článek 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
Článek Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis
Článek Correction: Perspectives of general dental practitioners on preventive, patient-centred, and evidence-based oral healthcare—A Q-methodology study
Článek Early detection and differential serodiagnosis of Mycoplasma hyorhinis and Mycoplasma hyosynoviae infections under experimental conditions
Článek No evidence of associations between ADHD and event-related brain potentials from a continuous performance task in a population-based sample of adolescent twins
Článek Antibiotic resistance of blood cultures in regional and tertiary hospital settings of Tyrol, Austria (2006-2015): Impacts & trends
Článek Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP
Článek Dopamine receptor antagonists effects on low-dimensional attractors of local field potentials in optogenetic mice
Článek Cell-free DNA levels of twins and sibling pairs indicate individuality and possible use as a personalized biomarker
Článek Dinosaur ichnology and sedimentology of the Chignik Formation (Upper Cretaceous), Aniakchak National Monument, southwestern Alaska; Further insights on habitat preferences of high-latitude hadrosaurs
Článek Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation – A finite element modeling study
Článek Catastrophic factors involved in road accidents: Underlying causes and descriptive analysis
Článek Seroprevalence of anti-Toxoplasma gondii antibodies in wild boars (Sus scrofa), hunting dogs, and hunters of Brazil
Článek Detection and determination of stability of the antibiotic residues in cow’s milk
Článek Neural minimization methods (NMM) for solving variable order fractional delay differential equations (FDDEs) with simulated annealing (SA)
Článek Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana
Článek Characteristics and costs in adults with acute poisoning admitted to the emergency department of a university hospital in Belgium
Článek War pact model of shrinking networks
Článek Treatment outcomes based on radiation therapy fields for bifocal germinoma: Synchronous or disseminated disease?
Článek Effect of an intensive 3-day social cognitive treatment (can do treatment) on control self-efficacy in patients with relapsing remitting multiple sclerosis and low disability: A single-centre randomized controlled trial
Článek Successful development of methodology for detection of hapten-specific contact hypersensitivity (CHS) memory in swine
Článek Postural changes in optic nerve and optic nerve sheath diameters in postural orthostatic tachycardia syndrome and spontaneous intracranial hypotension: A cohort study
Článek Attitudes and referral practices for pre-exposure prophylaxis (PrEP) among HIV rapid testers and case managers in Philadelphia: A mixed methods study
Článek The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study
Článek Endovascular therapy of direct dural carotid cavernous fistulas – A therapy assessment study including long-term follow-up patient interviews
Článek Frozen by stress: Stress increases scope insensitivity
Článek An extinction event in planktonic Foraminifera preceded by stabilizing selection
Článek Optimal seismic retrofitting techniques for URM school buildings located in the southwestern Iberian peninsula
Článek The effect of a hiding box on stress levels and body weight in Dutch shelter cats; a randomized controlled trial
Článek Early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: A systematic review and meta-analysis
Článek Deep brain activation patterns involved in virtual gait without and with a doorway: An fMRI study
Článek Infant dietary intake of yogurt and cheese and gastroenteritis at 1 year of age: The Japan Environment and Children’s Study
Článek Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel
Článek Anesthesia during deployment of a military forward surgical unit in low income countries: A register study of 1547 anesthesia cases
Článek CsBZIP40, a BZIP transcription factor in sweet orange, plays a positive regulatory role in citrus bacterial canker response and tolerance
Článek Differences in perceived popularity and social preference between bullying roles and class norms
Článek Identity and pathogenicity of some fungi associated with hazelnut (Corylus avellana L.) trunk cankers in Oregon
Článek Fermented cereal-based Munkoyo beverage: Processing practices, microbial diversity and aroma compounds
Článek Associations between focus constructions and levels of exhaustivity: An experimental investigation of Chinese
Článek Measurement invariance tests of revisions to archaically worded items in the Mach IV scale
Článek Give science and peace a chance: Speeches by Nobel laureates in the sciences, 1901-2018
Článek The effect of food anticipation on cognitive function: An eye tracking study
Článek Adaptation of H3N2 canine influenza virus to feline cell culture
Článek A meta-analysis of crop response patterns to nitrogen limitation for improved model representation
Článek Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
Článek Does antibiotic use accelerate or retard cutaneous repair? A systematic review in animal models
Článek Transforming growth factor beta 1 induces methylation changes in lung fibroblasts
Článek Hepatic disease and the risk of mortality of Vibrio vulnificus necrotizing skin and soft tissue infections: A systematic review and meta-analysis
Článek Diagnostic accuracy of midkine on hepatocellular carcinoma: A meta-analysis
Článek Phosphorus-mediated alleviation of aluminum toxicity revealed by the iTRAQ technique in Citrus grandis roots
Článek Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization
Článek Management strategies for vaccinated animals after an outbreak of foot-and-mouth disease and the impact on return to trade
Článek RNA-Seq analysis reveals an essential role of tyrosine metabolism pathway in response to root-rot infection in Gerbera hybrida
Článek SpliceHetero: An information theoretic approach for measuring spliceomic intratumor heterogeneity from bulk tumor RNA-seq
Článek Large-scale phylogenomic analysis suggests three ancient superclades of the WUSCHEL-RELATED HOMEOBOX transcription factor family in plants
Článek Plasma sCD36 as non-circadian marker of chronic circadian disturbance in shift workers
Článek A cross sectional comparison of drug use indicators using WHO methodology in primary level hospitals participating in an Auditable Pharmaceutical Transactions and Services program versus non-APTS primary hospitals in Southern Ethiopia
Článek Trends in NBA and Euroleague basketball: Analysis and comparison of statistical data from 2000 to 2017
Článek Liquid biopsies for omics-based analysis in sentinel mussels
Článek Reporting biases in self-assessed physical and cognitive health status of older Europeans
Článek Trends in the characteristics of acute primary angle closure in Korea over the past 10-years
Článek Obesity-associated insulin resistance adversely affects skin function
Článek First-line treatments in EGFR-mutated advanced non-small cell lung cancer: A network meta-analysis
Článek In vivo human lower limb muscle architecture dataset obtained using diffusion tensor imaging
Článek Tobacco smoke exposure as a risk factor for human papillomavirus infections in women 18-26 years old in the United States
Článek The trigger-information-response model: Exploring health literacy during the first six months following a kidney transplantation
Článek Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
Článek The development of an evidence-based street food vending model within a socioecological framework: A guide for African countries
Článek Sociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015
Článek Patient navigation services for cancer care in low-and middle-income countries: A scoping review
Článek Weather extremes and perinatal mortality – Seasonal and ethnic differences in northern Sweden, 1800-1895
Článek Cognitive, relational and task crafting: Spanish adaptation and analysis of psychometric properties of the Job Crafting Questionnaire
Článek Maternal and perinatal death surveillance and response in Ethiopia: Achievements, challenges and prospects
Článek Identification and characterisation of capidermicin, a novel bacteriocin produced by Staphylococcus capitis
Článek Joint emulation of Earth System Model temperature-precipitation realizations with internal variability and space-time and cross-variable correlation: fldgen v2.0 software description
Článek Extensive culturomics of 8 healthy samples enhances metagenomics efficiency
Článek Macroepidemiological aspects of porcine reproductive and respiratory syndrome virus detection by major United States veterinary diagnostic laboratories over time, age group, and specimen
Článek Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study
Článek Correction: Human indole(ethyl)amine-N-methyltransferase (hINMT) catalyzed methylation of tryptamine, dimethylsulfide and dimethylselenide is enhanced under reducing conditions - A comparison between 254C and 254F, two common hINMT variants
Článek Myofibrillar function differs markedly between denervated and dexamethasone-treated rat skeletal muscles: Role of mechanical load
Článek Quantitation of eumelanin and pheomelanin markers in diverse biological samples by HPLC-UV-MS following solid-phase extraction
Článek Kinetics of mean platelet volume predicts mortality in patients with septic shock
Článek An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma
Článek Combining CDK4/6 inhibitors ribociclib and palbociclib with cytotoxic agents does not enhance cytotoxicity
Článek Association of Medicaid expansion with health insurance coverage by marital status and sex
Článek Are current approaches for measuring access to clean water and sanitation inclusive of people with disabilities? Comparison of individual- and household-level access between people with and without disabilities in the Tanahun district of Nepal
Článek A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage
Článek Monitoring Universal Health Coverage (UHC) in high Tuberculosis burden countries: Tuberculosis mortality an important tracer of UHC service coverage
Článek RCT evaluation of Skhokho: A holistic school intervention to prevent gender-based violence among South African Grade 8s
Článek On the use of Action Units and fuzzy explanatory models for facial expression recognition
Článek A systematic review of complementary and alternative medicine in oncology: Psychological and physical effects of manipulative and body-based practices
Článek What factors best explain attitudes to snow leopards in the Nepal Himalayas?
Článek Determinants of temperature sensitivity of soil respiration with the decline of a foundation species
Článek Mindfulness meditation, time judgment and time experience: Importance of the time scale considered (seconds or minutes)
Článek Regional, institutional, and departmental factors associated with gender diversity among BS-level chemical and electrical engineering graduates
Článek Transepithelial transport of P-glycoprotein substrate by the Malpighian tubules of the desert locust
Článek Sex affects immunolabeling for histone 3 K27me3 in the trophectoderm of the bovine blastocyst but not labeling for histone 3 K18ac
Článek A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan
Článek Replacing plasma membrane outer leaflet lipids with exogenous lipid without damaging membrane integrity
Článek Accurate dried blood spots collection in the community using non-medically trained personnel could support scaling up routine viral load testing in resource limited settings
Článek Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study
Článek Antimicrobial efficacy of commercially available endodontic bioceramic root canal sealers: A systematic review
Článek The motility-based swim-up technique separates bull sperm based on differences in metabolic rates and tail length
Článek Synbiotic supplementation to decrease Salmonella colonization in the intestine and carcass contamination in broiler birds
Článek Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease
Článek States with higher minimum wages have lower STI rates among women: Results of an ecological study of 66 US metropolitan areas, 2003-2015
Článek Weakening the subjective sensation of own hand ownership does not interfere with rapid finger movements
Článek Identification of DNA methyltransferases and demethylases in Solanum melongena L., and their transcription dynamics during fruit development and after salt and drought stresses
Článek Environmental conditions for Jamestown Canyon virus correlated with population-level resource selection by white-tailed deer in a suburban landscape
Článek The contribution of linear perspective cues and texture gradients in the perceptual rescaling of stimuli inside a Ponzo illusion corridor
Článek Cerebral blood flow imbalance is associated with motor outcome after pediatric arterial ischemic stroke
Článek Particularly neglected in countries with other challenges: High Toxoplasma gondii seroprevalence in pregnant women in Kabul, Afghanistan, while a low proportion know about the parasite
Článek Implementing advance care planning in routine nursing home care: The development of the theory-based ACP+ program
Článek Identifying genetic lineages through shape: An example in a cosmopolitan marine turtle species using geometric morphometrics
Článek The causality of borrowing: Lexical loans in Eurasian languages
Článek The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study
Článek Gaze and body cues interplay during interactive requests
Článek Acetylcholine-mediated top-down attention improves the response to bottom-up inputs by deformation of the attractor landscape
Článek Deep architectures for long-term stock price prediction with a heuristic-based strategy for trading simulations
Článek Vaccination status of patients using anti-TNF therapy and the physicians’ behavior shaping the phenomenon: Mixed-methods approach
Článek Organizational justice and illness reporting among Japanese employees with chronic diseases
Článek CavBench: A benchmark for protein cavity detection methods
Článek Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015
Článek Prevalence of methicillin-resistant Staphylococcus aureus in healthy Chinese population: A system review and meta-analysis
Článek Suppression treatment differentially influences the microbial community and the occurrence of broad host range plasmids in the rhizosphere of the model cover crop Avena sativa L.
Článek Risk of pneumonia among residents living near goat and poultry farms during 2014-2016
Článek Lipid levels after childbirth and association with number of children: A population-based cohort study
Článek Birth outcomes in women who have taken adalimumab in pregnancy: A prospective cohort study
Článek ECMO with vasopressor use during early endotoxic shock: Can it improve circulatory support and regional microcirculatory blood flow?
Článek Effects of dietary intake and nutritional status on cerebral oxygenation in patients with chronic kidney disease not undergoing dialysis: A cross-sectional study
Článek Micro-RNA 150-5p predicts overt heart failure in patients with univentricular hearts
Článek Flexible learning spaces facilitate interaction, collaboration and behavioural engagement in secondary school
Článek Clinical significance and prognostic role of hypoxia-induced microRNA 382 in gastric adenocarcinoma
Článek Genome-wide investigation of superoxide dismutase (SOD) gene family and their regulatory miRNAs reveal the involvement in abiotic stress and hormone response in tea plant (Camellia sinensis)
Článek Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing
Článek Prevalence of Trypanosoma cruzi infection in active military population of The Colombian National Army gathered in five departments
Článek An observational study comparing HPV prevalence and type distribution between HPV-vaccinated and -unvaccinated girls after introduction of school-based HPV vaccination in Norway
Článek Sarcopenia as a prognostic factor for survival in patients with locally advanced gastroesophageal adenocarcinoma
Článek Increased aggression and reduced aversive learning in honey bees exposed to extremely low frequency electromagnetic fields
Článek Attending to design when developing complex health interventions: A qualitative interview study with intervention developers and associated stakeholders
Článek Increased fecundity of Aphis fabae on Vicia faba plants following seed or leaf inoculation with the entomopathogenic fungus Beauveria bassiana
Článek Is summer food intake a limiting factor for boreal browsers? Diet, temperature, and reproduction as drivers of consumption in female moose
Článek Characterization of sound scattering layers in the Bay of Biscay using broadband acoustics, nets and video
Článek Conducting human challenge studies in LMICs: A survey of researchers and ethics committee members in Thailand
Článek eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization
Článek Clinical use of SAND battery to evaluate language in patients with Progressive Supranuclear Palsy
Článek The interplay of personality and attitudes toward own aging across two decades of later life
Článek Robust automated reading of the skin prick test via 3D imaging and parametric surface fitting
Článek Reconstructing the population history of the sandy beach amphipod Haustorioides japonicus using the calibration of demographic transition (CDT) approach
Článek A psychoacoustic application for the adjustment of electrical hearing thresholds in cochlear implant patients
Článek Correction: Blue light-dependent human magnetoreception in geomagnetic food orientation
Článek Re-evaluation of a Tn5::gacA mutant of Pseudomonas syringae pv. tomato DC3000 uncovers roles for uvrC and anmK in promoting virulence
Článek Sugar-sweetened beverages and colorectal cancer risk in the California Teachers Study
Článek Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma
Článek The impact of shared knowledge on speakers’ prosody
Článek Effects of insecticides, fipronil and imidacloprid, on the growth, survival, and behavior of brown shrimp Farfantepenaeus aztecus
Článek Prevalence of pectus excavatum (PE), pectus carinatum (PC), tracheal hypoplasia, thoracic spine deformities and lateral heart displacement in thoracic radiographs of screw-tailed brachycephalic dogs
Článek Validation of the vignette-based German Exercise Causality Orientation Scale (G-ECOS)
Článek Hierarchical classification of snowmelt episodes in the Pyrenees using seismic data
Článek A national survey of videolaryngoscopes and alternative intubation devices in Hungary
Článek The relevance of U.S. Strategic Highway Safety Plans in a future context
Článek Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs
Článek Anti-inflammatory effects induced by ultralow concentrations of bupivacaine in combination with ultralow concentrations of sildenafil (Viagra) and vitamin D3 on inflammatory reactive brain astrocytes
Článek Access to unauthorized hepatitis C generics: Perception and knowledge of physicians, pharmacists, patients and non-healthcare professionals
Článek Urban commuting dynamics in response to public transit upgrades: A big data approach
Článek When resolution does matter: Modelling indirect contacts in dairy farms at different levels of detail
Článek Molecular epidemiology of Mycoplasma hyorhinis porcine field isolates in the United States
Článek Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via β2-adrenoceptor stimulation
Článek Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia
Článek Identification of social relation within pedestrian dyads
Článek Blood donation and health status based on SF-36: The mediating effect of cognition in blood donation
Článek The cost-effectiveness of controlling cervical cancer using a new 9-valent human papillomavirus vaccine among school-aged girls in Australia
Článek Inactivation of chronic wasting disease prions using sodium hypochlorite
Článek Analysing linear multivariate pattern transformations in neuroimaging data
Článek Ecological aesthetic assessment of a rebuilt wetland restored from farmland and management implications for National Wetland Parks
Článek A method for predicting background advertisement exposure parameters in sporting events: Televised football game approach
Článek Self-reported and experimentally induced self-disgust is heightened in Parkinson’s disease: Contribution of behavioural symptoms
Článek Associations between nocturnal sleep duration, midday nap duration and body composition among adults in Southwest China
Článek Short-term effects of video gaming on brain response during working memory performance
Článek Molecular detection and genetic characterization of Bartonella species from rodents and their associated ectoparasites from northern Tanzania
Článek Estimation of the number of HCV-positive patients in Italy
Článek Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa
Článek Insights into the behavior of six rationally designed peptides based on Escherichia coli’s OmpA at the water-dodecane interface
Článek Identification of muscle-specific candidate genes in Simmental beef cattle using imputed next generation sequencing
Článek A game theoretic setting of capitation versus fee-for-service payment systems
Článek In utero exposure to economic fluctuations and birth outcomes: An analysis of the relevance of the local unemployment rate in Brazilian state capitals
Článek QTL mapping for aluminum tolerance in RIL population of soybean (Glycine max L.) by RAD sequencing
Článek Establishing an infrastructure for collaboration in primate cognition research
Článek Evaluation of left ventricular dimension and systolic function by standard transthoracic echocardiography before and 24-hours after percutaneous closure of patent ductus arteriosus in 120 dogs
Článek Modeling environmental variability and network formation among pastoral nomadic households: Implications for the rise of the Mongol Empire
Článek Changes in real-life practice for hepatocellular carcinoma patients in the Republic of Korea over a 12-year period: A nationwide random sample study
Článek Correction: Homology analysis of malware based on ensemble learning and multifeatures
Článek Illness beliefs and emotional responses in mildly disabled stroke survivors: A qualitative study
Článek Extended-wavelength diffuse reflectance spectroscopy with a machine-learning method for in vivo tissue classification
Článek Modeling the natural history of fatty liver using lifestyle–related risk factors: Effects of body mass index (BMI) on the life–course of fatty liver
Článek Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice
Článek Educational achievement at age 9.5 years of children born to mothers maintained on methadone during pregnancy
Článek Comparative transcriptome analysis of galls from four different host plants suggests the molecular mechanism of gall development
Článek Experiences with peer support for breastfeeding in Beirut, Lebanon: A qualitative study
Článek Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer
Článek Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
Článek Correction: Functional atlases for analysis of motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation
Článek Correction: Estimating Body Composition in Adolescent Sprint Athletes: Comparison of Different Methods in a 3 Years Longitudinal Design
Článek Quality of labor and birth care in Sindh Province, Pakistan: Findings from direct observations at health facilities
Článek A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T
Článek Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis
Článek Intrabladder pressure as predictor of intra-abdominal pressure in horses
Článek Pollock avoided hydrodynamic instabilities to paint with his dripping technique
Článek Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants
Článek Photo-degradation dynamics of five neonicotinoids: Bamboo vinegar as a synergistic agent for improved functional duration
Článek Use of acoustic emission to identify novel candidate biomarkers for knee osteoarthritis (OA)
Článek Cetacean biodiversity, spatial and temporal trends based on stranding records (1920-2016), Victoria, Australia
Článek Neutrophil elastase inhibitor purification strategy from cowpea seeds
Článek Correction: Hafting of Middle Paleolithic tools in Latium (central Italy): New data from Fossellone and Sant’Agostino caves
Článek Coherent poly propagation materials with 3-dimensional photonic control over visible light
Článek Characterization of Worldwide Olive Germplasm Banks of Marrakech (Morocco) and Córdoba (Spain): Towards management and use of olive germplasm in breeding programs
Článek Can non-pharmacological interventions reduce hospital admissions in people with dementia? A systematic review
Článek Metarhizium robertsii ammonium permeases (MepC and Mep2) contribute to rhizoplane colonization and modulates the transfer of insect derived nitrogen to plants
Článek Genotyping and antimicrobial resistance of Streptococcus uberis isolated from bovine clinical mastitis
Článek Isotopic compositions of ground ice in near-surface permafrost in relation to vegetation and microtopography at the Taiga–Tundra boundary in the Indigirka River lowlands, northeastern Siberia
Článek Financial inclusion and intimate partner violence: What does the evidence suggest?
Článek Are intestinal helminths playing a positive role in tuberculosis risk? A systematic review and meta-analysis
Článek Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
Článek Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer
Článek Take one step backward to move forward: Assessment of genetic diversity and population structure of captive Asian woolly-necked storks (Ciconia episcopus)
Článek Money doesn’t matter! Householders’ intentions to reduce standby power are unaffected by personalised pecuniary feedback
Článek Validating a scale to measure engineers’ perceived self-efficacy for engineering education outreach
Článek Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
Článek Nursing students and nurses’ knowledge and attitudes regarding children’s pain: A comparative cross-sectional study
Článek Inter-method and anatomical correlates of episodic memory tests in the Alzheimer’s Disease spectrum
Článek Knowledge, attitudes and medical practice regarding hepatitis B prevention and management among healthcare workers in Northern Vietnam
Článek Development and validation of a symptom assessment tool for postmicturition dribble: A prospective, multicenter, observational study in Korea
Článek Identification of closely related Ixodes species by protein profiling with MALDI-TOF mass spectrometry
Článek When calculators lie: A demonstration of uncritical calculator usage among college students and factors that improve performance
Článek Socio-economic characteristics and career intentions of the WiSDOM health professional cohort in South Africa
Článek Correction: Neural computational model GrowthEstimate: A model for studying living resources through digestive efficiency
Článek Social proximity in dairy calves is affected by differences in pessimism
Článek Amphibian skin-associated Pigmentiphaga: Genome sequence and occurrence across geography and hosts
Článek Expanded consumer niche widths may signal an early response to spatial protection
Článek Moral grandstanding in public discourse: Status-seeking motives as a potential explanatory mechanism in predicting conflict
Článek Adipose stem cells in reparative goat mastitis mammary gland
Článek Seventy-five mosses and liverworts found frozen with the late Neolithic Tyrolean Iceman: Origins, taphonomy and the Iceman’s last journey
Článek Hyaluronic acid and epidermal growth factor improved the bovine embryo quality by regulating the DNA methylation and expression patterns of the focal adhesion pathway
Článek Associations among knowledge, attitudes, and practices toward palliative care consultation service in healthcare staffs: A cross-sectional study
Článek A novel, wearable, electronic visual aid to assist those with reduced peripheral vision
Článek Genetic diversity and population structure of the Mediterranean sesame core collection with use of genome-wide SNPs developed by double digest RAD-Seq
Článek Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
Článek Mobile health-based physical activity intervention for individuals with spinal cord injury in the community: A pilot study
Článek Factors influencing cultivated ginseng (Panax ginseng C. A. Meyer) bioactive compounds
Článek Estimation of soil pH with geochemical indices in forest soils
Článek Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development
Článek Correlates of longitudinal leukocyte telomere length in the Costa Rican Longevity Study of Healthy Aging (CRELES): On the importance of DNA collection and storage procedures
Článek Collaboration and followership: A stochastic model for activities in social networks
Článek Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China
Článek Comparison of corneal elevation and pachymetry measurements made by two state of the art corneal tomographers with different measurement principles
Článek Use of a pressure-sensing walkway system for biometric assessment of gait characteristics in goats
Článek Current status and direct medical cost of amyotrophic lateral sclerosis in the region of Catalonia: A population-based analysis
Článek Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
Článek Can work climate foster pro-environmental behavior inside and outside of the workplace?
Článek Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA
Článek Pelvic alignment changes during the perinatal period
Článek Interatrial blocks prevalence and risk factors for human immunodeficiency virus-infected persons
Článek Life-course trajectories of body mass index and subsequent cardiovascular risk among Chinese population
Článek Inhibitory interaction networks among coevolved Streptomyces populations from prairie soils
Článek Exploiting contextual information to improve call prediction
Článek Visual inputs decrease brain activity in frontal areas during silent lipreading
Článek The synergistic effects of TaAGP.L-B1 and TaSSIVb-D mutations in wheat lead to alterations of gene expression patterns and starch content in grain development
Článek Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
Článek Robust, real-time generic detector based on a multi-feature probabilistic method
Článek Maize leaves drought-responsive genes revealed by comparative transcriptome of two cultivars during the filling stage
Článek Xenon lamps used for fruit surface sterilization can increase the content of total flavonols in leaves of Lactuca sativa L. without any negative effect on net photosynthesis
Článek An alternative procedure to obtain the mortality rate with non-linear functions: Application to the case of the Spanish population
Článek Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
Článek Longitudinal assessment of post-surgical physical activity in endometrial and ovarian cancer patients
Článek THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images
Článek Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice
Článek Proteomic analysis of Escherichia coli detergent-resistant membranes (DRM)
Článek Correction: Effect of curcuminoids and curcumin derivate products on thioredoxin-glutathione reductase from Taenia crassiceps cysticerci. Evidence suggesting a curcumin oxidation product as a suitable inhibitor
Článek Correction: Predicting childhood obesity using electronic health records and publicly available data
Článek Correction: Estimating the value of tropical coastal wetland habitats to fisheries: Caveats and assumptions
Článek Correction: The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers
Článek Determinants of frailty development and progression using a multidimensional frailty index: Evidence from the English Longitudinal Study of Ageing
Článek Supporting informed clinical trial decisions: Results from a randomized controlled trial evaluating a digital decision support tool for those with intellectual disability
Článek BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin
Článek Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
Článek Hepatopulmonary syndrome has low prevalence of pulmonary vascular abnormalities on chest computed tomography
Článek Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
Článek Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15
Článek The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population
Článek Expression of Concern: The Coordination of Cell Growth during Fission Yeast Mating Requires Ras1-GTP Hydrolysis
Článek Correction: Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells
Článek Relationship between self-disclosure to first acquaintances and subjective well-being in people with schizophrenia spectrum disorders living in the community
Článek Remarkable cell recovery from cerebral ischemia in rats using an adaptive escalator-based rehabilitation mechanism
Článek Integrating environmental and neighborhood factors in MaxEnt modeling to predict species distributions: A case study of Aedes albopictus in southeastern Pennsylvania
Článek Post-overdose interventions triggered by calling 911: Centering the perspectives of people who use drugs (PWUDs)
Článek The prevalence of intimate partner violence among couples signing up for universally offered parent preparation
Článek Analysis of gear surface morphology based on gray level co-occurrence matrix and fractal dimension
Článek Abiotic, present-day and historical effects on species, functional and phylogenetic diversity in dry grasslands of different age
Článek Clonality analysis of pulmonary tumors by genome-wide copy number profiling
Článek A relictual troglomorphic harvestman discovered in a volcanic cave of western Argentina: Otilioleptes marcelae, new genus, new species, and Otilioleptidae, new family (Arachnida, Opiliones, Gonyleptoidea)
Článek HIV drug resistance in persons who inject drugs enrolled in an HIV prevention trial in Indonesia, Ukraine, and Vietnam: HPTN 074
Článek Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery
Článek Regulation of nitrogen availability results in changes in grain protein content and grain storage subproteomes in barley (Hordeum vulgare L.)
Článek Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update
Článek Longitudinal trends of and factors associated with inappropriate antibiotic prescribing for non-bacterial acute respiratory tract infection in Japan: A retrospective claims database study, 2012–2017
Článek Revealing users’ experience and social interaction outcomes following a web-based smoking prevention intervention for adolescents: A qualitative study
Článek Coordination of human movements resulting in motor strategies exploited by skilled players during a throwing task
Článek Impact of pericardiectomy on exercise capacity and sleep of patients with chronic constrictive pericarditis
Článek Blue-violet light decreases VEGFa production in an in vitro model of AMD
Článek Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach
Článek Speed of processing training and depression in assisted and independent living: A randomized controlled trial
Článek Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
Článek What happens in the brain of meditators when perception changes but not the stimulus?
Článek Are degree of urbanisation and travel times to healthcare services associated with the processes of care and outcomes of heart failure? A retrospective cohort study based on administrative data
Článek A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
Článek Influence of transcutaneous vagus nerve stimulation on cardiac vagal activity: Not different from sham stimulation and no effect of stimulation intensity
Článek Co-prescription network reveals social dynamics of opioid doctor shopping
Článek Contractile properties of superficial skeletal muscle affect postural control in healthy young adults: A test of the rambling and trembling hypothesis
Článek Does intrauterine crowding affect the force generating capacity and muscle composition of the piglet front limb?
Článek Correction: Measuring compassionate healthcare with the 12-item Schwartz Center Compassionate Care Scale
Článek Facilitators and barriers to traditional medicine use among cancer patients in Malawi
Článek Expression of CMV protein pp65 in cutaneous malignant melanoma
Článek The evolution of mental health outcomes across a combat deployment cycle: A longitudinal study of a Guam-based National Guard unit
Článek Caesarean section delivery and childhood obesity in a British longitudinal cohort study
Článek Incidence, characteristics, and mortality of infective endocarditis in France in 2011
Článek Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis
Článek Evaluation of the bacterial ocular surface microbiome in clinically normal cats before and after treatment with topical erythromycin
Článek Histological and developmental insights into the herbivorous dentition of tapinocephalid therapsids
Článek Differential immunomodulation of T-cells by immunoglobulin replacement therapy in primary and secondary antibody deficiency
Článek A longitudinal study on perceived health in cardiovascular patients: The role of conscientiousness, subjective wellbeing and cardiac self-efficacy
Článek The effectiveness of interferon beta versus glatiramer acetate and natalizumab versus fingolimod in a Polish real-world population
Článek Interactions of Streptococcus suis serotype 9 with host cells and role of the capsular polysaccharide: Comparison with serotypes 2 and 14
Článek Honey bee and native solitary bee foraging behavior in a crop with dimorphic parental lines
Článek A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
Článek Correction: Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants
Článek A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms
Článek Health workers’ perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria
Článek Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods
Článek The increasing importance of fellowships and career development awards in the careers of early-stage biomedical academic researchers
Článek Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components
Článek Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
Článek Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development
Článek Distance to large rivers affects fish diversity patterns in highly dynamic streams of Central Amazonia
Článek Real vs. immersive-virtual emotional experience: Analysis of psycho-physiological patterns in a free exploration of an art museum
Článek Modulation of brain tumor risk by genetic SNPs in PARP1gene: Hospital based case control study
Článek Processed meat intake and chronic disease morbidity and mortality: An overview of systematic reviews and meta-analyses
Článek Modeling ENSO impact on rice production in the Mekong River Delta
Článek The feasibility of a behavioral group intervention after weight-loss surgery: A randomized pilot trial
Článek EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases
Článek A review of a 13-month period of FilmArray Meningitis/Encephalitis panel implementation as a first-line diagnosis tool at a university hospital
Článek Increased BMI has a linear association with late-onset preeclampsia: A population-based study
Článek Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model
Článek Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy
Článek Telomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations
Článek Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP
Článek Impact of faecal calprotectin measurement on clinical decision-making in patients with Crohn’s disease and ulcerative colitis
Článek Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells
Článek Autophagy is important to the acidogenic metabolism of Aspergillus niger
Článek Continuous ratings of movie watching reveal idiosyncratic dynamics of aesthetic enjoyment
Článek Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis
Článek Enhancing genomic selection by fitting large-effect SNPs as fixed effects and a genotype-by-environment effect using a maize BC1F3:4 population
Článek Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry
Článek Microbial induced solidification and stabilization of municipal solid waste incineration fly ash with high alkalinity and heavy metal toxicity
Článek Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses
Článek A fault-tolerant aware scheduling method for fog-cloud environments
Článek Correction: BCG vaccination and tuberculosis prevention: A forty years cohort study, Monastir, Tunisia
Článek Correction: Perceptions among transgender women of factors associated with the access to HIV/AIDS-related health services in Yogyakarta, Indonesia
Článek Assessing the convergent validity between the automated emotion recognition software Noldus FaceReader 7 and Facial Action Coding System Scoring
Článek Deep learning based banana plant detection and counting using high-resolution red-green-blue (RGB) images collected from unmanned aerial vehicle (UAV)
Článek Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study
Článek Intraregional differences in renal function in the Northern Netherlands: The Lifelines Cohort Study
Článek Effects of MCHM on yeast metabolism
Článek Signaling impacts of GMO labeling on fruit and vegetable demand
Článek Dietary specialization depending on ecological context and sexual differences in Asiatic black bears
Článek Electronic device use and beverage related sugar and caffeine intake in US adolescents
Článek Correction: Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial
Článek Correction: Anatomical analysis of antebrachial cutaneous nerve distribution pattern and its clinical implications for sensory reconstruction
Článek Lack of detection of Candida nivariensis and Candida bracarensis among 440 clinical Candida glabrata sensu lato isolates in Kuwait
Článek Nonlinear dynamics captures brain states at different levels of consciousness in patients anesthetized with propofol
Článek Visual encounters on line transect surveys under-detect carnivore species: Implications for assessing distribution and conservation status
Článek Menstrual health communication among Indian adolescents: A mixed-methods study
Článek Fast fluorescence in situ hybridisation for the enhanced detection of MET in non-small cell lung cancer
Článek The influence of personality on the effect of iTBS after being stressed on cortisol secretion
Článek Parental and peer support and modelling in relation to domain-specific physical activity participation in boys and girls from Germany
Článek Oral delivery of water-soluble compounds to the phytoseiid mite Neoseiulus californicus (Acari: Phytoseiidae)
Článek Force perceptual bias caused by muscle activity in unimanual steering
Článek Correction: Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis
Článek Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium
Článek Providencia entomophila sp. nov., a new bacterial species associated with major olive pests in Tunisia
Článek Safety of intravitreal ziv-aflibercept in choroido-retinal vascular diseases: A randomised double-blind intervention study
Článek A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic
Článek Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study
Článek Emotionally expressed voices are retained in memory following a single exposure
Článek Megabenthic communities of the Ligurian deep continental shelf and shelf break (NW Mediterranean Sea)
Článek A randomized crossover trial comparing the Nifty cup to a medicine cup in preterm infants who have difficulty breastfeeding at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana
Článek The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
Článek Genomic impact of severe population decline in a nomadic songbird
Článek Evolution of high-sensitivity troponin-T and echocardiography parameters in patients undergoing high efficiency on-line hemodiafiltration versus conventional low-flux hemodialysis
Článek Full genome characterization of 12 citrus tatter leaf virus isolates for the development of a detection assay
Článek Intake of myo-inositol hexaphosphate and urinary excretion of inositol phosphates in Wistar rats: Gavage vs. oral administration with sugar
Článek Enhancing financial security of female sex workers through a community-led intervention in India: Evidence from a longitudinal survey
Článek In-silico prediction of novel genes responsive to drought and salinity stress tolerance in bread wheat (Triticum aestivum)
Článek Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
Článek Partitioning the risk of tuberculosis transmission in household contact studies
Článek Using satellite-measured relative humidity for prediction of Metisa plana’s population in oil palm plantations: A comparative assessment of regression and artificial neural network models
Článek A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects
Článek Emotional and behavioral problems, social competence and risk factors in 6–16-year-old students in Beijing, China
Článek Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis
Článek Involution of retinopathy of prematurity and neurodevelopmental outcomes after intravitreal bevacizumab treatment
Článek Travel demand and distance analysis for free-floating car sharing based on deep learning method
Článek Genome-wide identification, characterization, expression and enzyme activity analysis of coniferyl alcohol acetyltransferase genes involved in eugenol biosynthesis in Prunus mume
Článek Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype
Článek The high resource impact of reformatting requirements for scientific papers
Článek Egg yolk-free cryopreservation of bull semen
Článek Fine epitope mapping of glycoprotein Gn in Guertu virus
Článek Are hospital nurse staffing practices associated with postoperative cardiac events and death? A systematic review
Článek Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction
Článek Aging and the wandering brain: Age-related differences in the neural correlates of stimulus-independent thoughts
Článek Elucidating stygofaunal trophic web interactions via isotopic ecology
Článek Experimental characterization of two archaeal inosine 5'-monophosphate cyclohydrolases
Článek Scientist and data architect collaborate to curate and archive an inner ear electrophysiology data collection
Článek No effect of triple-pulse TMS medial to intraparietal sulcus on online correction for target perturbations during goal-directed hand and foot reaches
Článek Correction: Controlling Social Stress in Virtual Reality Environments
Článek TNF-α is responsible for the contribution of stromal cells to osteoclast and odontoclast formation during orthodontic tooth movement
Článek Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children
Článek Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease
Článek To tweet or not to tweet, that is the question: A randomized trial of Twitter effects in medical education
Článek True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential
Článek Impact of the detection of ζ-globin chains and hemoglobin Bart’s using immunochromatographic strip tests for α0-thalassemia (--SEA) differential diagnosis
Článek Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort
Článek Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
Článek Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana
Článek Correction: Precision public health: Mapping socioeconomic disparities in opioid dispensations at Swedish pharmacies by Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)
Článek Epidemiological, clinical and laboratory characteristics of the measles resurgence in the Republic of Serbia in 2014-2015
Článek Macro-charcoal accumulation in floodplain wetlands: Problems and prospects for reconstruction of fire regimes and environmental conditions
Článek Stage at diagnosis and stage-specific survival of breast cancer in Latin America and the Caribbean: A systematic review and meta-analysis
Článek Correction: Retraction: Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway
Článek TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo
Článek Clinical impact of intraoperative hyperlactatemia during craniotomy
Článek Intubation with channeled versus non-channeled video laryngoscopes in simulated difficult airway by junior doctors in an out-of-hospital setting: A crossover manikin study
Článek Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates
Článek Sex-specific differences in risk factors of lymph node metastasis in patients with early gastric cancer
Článek The impact of electroconvulsive therapy on the spatial QRS-T angle and cardiac troponin T concentration in psychiatric patients
Článek Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases
Článek Comparison of cancer prevalence between patients with glomerulonephritis and the general population at the time of kidney biopsy
Článek Predictors of time to unfavorable treatment outcomes among patients with multidrug resistant tuberculosis in Oromia region, Ethiopia
Článek Experimentally validated simulation of coronary stents considering different dogboning ratios and asymmetric stent positioning
Článek The membrane effects of melittin on gastric and colorectal cancer
Článek Exclusive breastfeeding policy, practice and influences in South Africa, 1980 to 2018: A mixed-methods systematic review
Článek Hippocampal subfield volumes and pre-clinical Alzheimer’s disease in 408 cognitively normal adults born in 1946
Článek Uncorrected low hyperopia in young subjects induces postural instability even in those with clear visual acuity
Článek Membrane associated proteins of two Trichomonas gallinae clones vary with the virulence
Článek Awareness, current use of electronic cigarettes and associated smoking factors in Zhejiang Chinese adolescents
Článek Associations between pre-pregnancy BMI, gestational weight gain, and prenatal diet quality in a national sample
Článek Effects of continuous ketamine infusion on hemodynamics and mortality in critically ill children
Článek Optofluidic laser speckle image decorrelation analysis for the assessment of red blood cell storage
Článek Complete chloroplast genome sequence and phylogenetic analysis of Spathiphyllum 'Parrish'
Článek Strategic science communication as planned behavior: Understanding scientists’ willingness to choose specific tactics
Článek Understanding spatial patterns of soils for sustainable agriculture in northern Ethiopia’s tropical mountains
Článek Does Japan’s national nutrient-based dietary guideline improve lifestyle-related disease outcomes? A retrospective observational cross-sectional study
Článek Agitation near the end of life with dementia: An ethnographic study of care
Článek Encouraging perspective taking: Using narrative writing to induce empathy for others engaging in negative health behaviors
Článek Considerations of target surface area and the risk of radiosurgical toxicity
Článek Correction: A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells
Článek Effect of using immobilization device in fluoroscopic study in pediatric patient: Focused on radiation dose reduction in voiding cystourethrogram
Článek Temporal trends in breast cancer survival by race and ethnicity: A population-based cohort study
Článek Contamination of hospital surfaces with respiratory pathogens in Bangladesh
Článek The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver
Článek Association between hospital interval and survival in patients with oral cancer: A waiting time paradox
Článek Translating a stress management intervention for rural Latina breast cancer survivors: The Nuevo Amanecer-II
Článek Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial
Článek Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning
Článek Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
Článek Korean soybean core collection: Genotypic and phenotypic diversity population structure and genome-wide association study
Článek Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
Článek Measurement of structural integrity of the spinal cord in patients with amyotrophic lateral sclerosis using diffusion tensor magnetic resonance imaging
Článek Improved clinical outcome after medial open-wedge osteotomy despite cartilage lesions in the lateral compartment
Článek Rapid and structure-specific cellular uptake of selected steroids
Článek Avoiding gambling harm: An evidence-based set of safe gambling practices for consumers
Článek Epidemiology of chronic pain in Ukraine: Findings from the World Mental Health Survey
Článek PIAS1 is not suitable as a urothelial carcinoma biomarker protein and pharmacological target
Článek Double triage to identify poorly annotated genes in maize: The missing link in community curation
Článek N-acetyl cysteine restores the fertility of vitrified–warmed mouse oocytes derived through ultrasuperovulation
Článek Architecture of population-differentiated polymorphisms in the human genome
Článek Linguistic neutrosophic power Muirhead mean operators for safety evaluation of mines
Článek Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes
Článek Exercise intensity-dependent effects of arm and leg-cycling on cognitive performance
Článek How information about perpetrators’ nature and nurture influences assessments of their character, mental states, and deserved punishment
Článek Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis
Článek In silico assessment of human Calprotectin subunits (S100A8/A9) in presence of sodium and calcium ions using Molecular Dynamics simulation approach
Článek Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging
Článek Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing
Článek Characteristics of complementary medicine therapists in Switzerland: A cross-sectional study
Článek Lack of generalization between explicit and implicit visuomotor learning
Článek Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population
Článek Effects of temperature and salinity on respiratory losses and the ratio of photosynthesis to respiration in representative Antarctic phytoplankton species
Článek Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique
Článek Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature
Článek Echocardiography overestimates LV mass in the elderly as compared to cardiac CT
Článek Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs)
Článek Molecular mechanism of antimicrobial activity of chlorhexidine against carbapenem-resistant Acinetobacter baumannii
Článek First identification of the benzimidazole resistance-associated F200Y SNP in the beta-tubulin gene in Ascaris lumbricoides
Článek Enterovirus 71 seroepidemiology in Taiwan in 2017 and comparison of those rates in 1997, 1999 and 2007
Článek Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
Článek 13C and 15N NMR identification of product compound classes from aqueous and solid phase photodegradation of 2,4,6-trinitrotoluene
Článek Off-target effects of CRISPRa on interleukin-6 expression
Článek Exploring the antimicrobial properties of dark-operating ceramic-based nanocomposite materials for the disinfection of indoor air
Článek Experienced males recognise and avoid mating with non-virgin females in the western flower thrips
Článek Liver transplantation in patients with a history of migration—A German single center comparative analysis
Článek Retraction: The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
Článek Correction: Understanding climate change from a global analysis of city analogues
Článek Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension
Článek The relationship between sleep quality, inappropriate medication use and frailty among older adults in aged care homes in Malaysia
Článek Clonal diversity and spatial genetic structure in the long-lived herb, Prairie trillium
Článek Medication histories documentation at the community pharmacy setting: A study from Jordan
Článek Population dynamics of an invasive bird parasite, Philornis downsi (Diptera: Muscidae), in the Galapagos Islands
Článek Because you had a bad day: General and daily relations between reactive temperament, emotion regulation, and depressive symptoms in youth
Článek Socioeconomic status and alcohol use disorders across the lifespan: A co-relative control study
Článek Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase
Článek Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation
Článek Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study
Článek Validation and perception of a key feature problem examination in neurology
Článek Gender affirmative HIV care framework: Decisions on feminizing hormone therapy (FHT) and antiretroviral therapy (ART) among transgender women
Článek Quantifying international human mobility patterns using Facebook Network data
Článek Localization and characterization of thyroid microcalcifications: A histopathological study
Článek Young children are the main victims of fast food induced obesity in Brazil
Článek Understanding self-reported importance of religion/spirituality in a North American sample of individuals at risk for familial depression: A principal component analysis
Článek Standing balance of professional ballet dancers and non-dancers under different conditions
Článek 30-day unplanned readmission rate in otolaryngology patients: A population-based study in Thuringia, Germany
Článek Physical exercise stimulates salivary secretion of cystatins
Článek Vintage electronics for trusted radiation measurements and verified dismantlement of nuclear weapons
Článek Keepin’ it real: Linguistic models of authenticity judgments for artificially generated rap lyrics
Článek Carbon emission reduction and profit distribution mechanism of construction supply chain with fairness concern and cap-and-trade
Článek Modulations of microbehaviour by associative memory strength in Drosophila larvae
Článek Changes in peak expiratory flow rates using two head-tilt/chin-lift maneuver angles in young healthy conscious volunteers
Článek 3D image analysis reveals differences of CD30 positive cells and network formation in reactive and malignant human lymphoid tissue (classical Hodgkin Lymphoma)
Článek Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
Článek 2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury
Článek Correction: Reducing growth and developmental problems in children: Development of an innovative postnatal risk assessment
Článek Comparative analysis of the vertebral pneumatization in pterosaurs (Reptilia: Pterosauria) and extant birds (Avialae: Neornithes)
Článek Associations between cognitive performance and sigma power during sleep in children with attention-deficit/hyperactivity disorder, healthy children, and healthy adults
Článek Retraction: MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1
Článek Comparing growth patterns of three species: Similarities and differences
Článek Iron is increased in the brains of ageing mice lacking the neurofilament light gene
Článek Economic evaluation of community acquired pneumonia management strategies: A systematic review of literature
Článek A participatory community case study of periurban coastal flood vulnerability in southern Ecuador
Článek Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
Článek Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
Článek MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex
Článek Knowledge, attitudes, and practices related to anthrax and animal care: A case-control study in Georgia
Článek Information diffusion in signed networks
Článek Nurses’ perspectives on their communication with patients in busy oncology wards: A qualitative study
Článek Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS
Článek ART is key to clearing oncogenic HPV genotypes (HR-HPV) in anal mucosa of HIV-positive MSM
Článek Retraction: Fluid–Structure Interaction-Based Biomechanical Perception Model for Tactile Sensing
Článek Correction: Role of Caveolin-1 in Atrial Fibrillation as an Anti-Fibrotic Signaling Molecule in Human Atrial Fibroblasts
Článek The French adaptation and validation of the Partners in Health (PIH) scale among patients with chronic conditions seen in primary care
Článek Depth inversion with a 3D structure influences brightness perception
Článek Analysis of group evolution prediction in complex networks
Článek Effect of aridity and dune type on rhizosphere soil bacterial communities of Caragana microphylla in desert regions of northern China
Článek Knowledge, attitudes, and practices related to TB among the general population of Ethiopia: Findings from a national cross-sectional survey
Článek Correction: Personality traits in companion dogs—Results from the VIDOPET
Článek MANET 3.0: Hierarchy and modularity in evolving metabolic networks
Článek Agreement study on gait assessment using a video-assisted rating method in patients with idiopathic normal-pressure hydrocephalus
Článek Single fixed low-dose rituximab as induction therapy suppresses de novo donor-specific anti-HLA antibody production in ABO compatible living kidney transplant recipients
Článek Myomesin is part of an integrity pathway that responds to sarcomere damage and disease
Článek Acute normobaric hypoxia does not affect the simultaneous exercise-induced increase in circulating BDNF and GDNF in young healthy men: A feasibility study
Článek Systematic investigation on quad-metallic AgAuPdPt and tri-metallic AuPdPt NPs through the solid-state dewetting of quad-layer Ag/Au/Pd/Pt thin films on c-plane sapphire
Článek Video lecturing in Clicker-assisted English flipped class
Článek Significant changes of the choroid in patients with ocular ischemic syndrome and symptomatic carotid artery stenosis
Článek Skewed T cell responses to Epstein-Barr virus in long-term asymptomatic kidney transplant recipients
Článek Candidate genes expression profiling during wilting in chickpea caused by Fusarium oxysporum f. sp. ciceris race 5
Článek Host plants influence the composition of the gut bacteria in Henosepilachna vigintioctopunctata
Článek ‘We are all serving the same Ugandans’: A nationwide mixed-methods evaluation of private sector surgical capacity in Uganda
Článek The association between flavor capsule cigarette use and sociodemographic variables: Evidence from Chile
Článek Relations between gross motor skills and executive functions, controlling for the role of information processing and lapses of attention in 8-10 year old children
Článek Linalool acts as a fast and reversible anesthetic in Hydra
Článek Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka
Článek Using isotemporal substitution to predict the effects of changing physical behaviour on older adults’ cardio-metabolic profiles
Článek Adherence to general medical checkup and cancer screening guidelines according to self-reported smoking status: Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2012
Článek Do older English adults exhibit day-to-day compensation in sedentary time and in prolonged sedentary bouts? An EPIC-Norfolk cohort analysis
Článek Linoleic acid supplementation of cell culture media influences the phospholipid and lipid profiles of human reconstructed adipose tissue
Článek Correction: Factors associated with hospitalization and death among TB/HIV co-infected persons in Porto Alegre, Brazil
Článek An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
Článek Reporting adverse events related to medical devices: A single center experience from a tertiary academic hospital
Článek Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism
Článek Estimating biodiversity changes in the Camargue wetlands: An expert knowledge approach
Článek Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
Článek Retraction: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis
Článek Lipoarabinomannan from Mycobacterium indicus pranii shows immunostimulatory activity and induces autophagy in macrophages
Článek A measure of inconsistencies in intertemporal choice
Článek A novel radiopaque tissue marker for soft tissue localization and in vivo length and area measurements
Článek Anatomical, histological and computed tomography comparisons of the eye and adnexa of crab-eating fox (Cerdocyon thous) to domestic dogs
Článek Subpopulation augmentation among habitat patches as a tool to manage an endangered Mojave Desert wetlands-dependent rodent during anthropogenic restricted water climate regimes
Článek Characteristics of CD5-positive diffuse large B-cell lymphoma among Koreans: High incidence of BCL2 and MYC double-expressors
Článek Fossil tabulate corals reveal outcrops of Paleozoic sandstones in the Atlantic Coastal Plain Province, Southeastern USA
Článek Coming and going – Historical distributions of the European oyster Ostrea edulis Linnaeus, 1758 and the introduced slipper limpet Crepidula fornicata Linnaeus, 1758 in the North Sea
Článek Behavioral predictors of subsequent respiratory illness signs in dogs admitted to an animal shelter
Článek Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
Článek Can emotional intelligence be improved? A randomized experimental study of a business-oriented EI training program for senior managers
Článek Genetic variability in landraces populations and the risk to lose genetic variation. The example of landrace ‘Kyperounda’ and its implications for ex situ conservation
Článek Sleep problems are a strong predictor of stress-related metabolic changes in police officers. A prospective study
Článek Age, sex and primary care setting differences in patients’ perception of community healthcare seeking behaviour towards health services
Článek Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury
Článek Effects of model inaccuracies on reaching movements with intermittent control
Článek C-reactive protein to albumin ratio predicts the outcome in renal cell carcinoma: A meta-analysis
Článek A new synthetic lure for management of the invasive giant African snail, Lissachatina fulica
Článek Bridging solvent molecules mediate RNase A – Ligand binding
Článek Variation in methods, results and reporting in electronic health record-based studies evaluating routine care in gout: A systematic review
Článek The use of prophylactic intra-aortic balloon pump in high-risk patients undergoing coronary artery bypass grafting
Článek Compliance with clinical guidelines for breast cancer management: A population-based study of quality-of-care indicators in France
Článek Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis
Článek Acute effects of differential learning on football kicking performance and in countermovement jump
Článek Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
Článek Play like me: Similarity in playfulness promotes social play
Článek Awareness of family health history in a predominantly young adult population
Článek Care pathways during a child’s final illness in rural South Africa: Findings from a social autopsy study
Článek Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials
Článek Allele-specific enhancer interaction at the Peg3 imprinted domain
Článek Is spontaneous normalization of systolic blood pressure within 24 hours after ischemic stroke onset related with favorable outcomes?
Článek Mixotrophic cultivation of Spirulina platensis in dairy wastewater: Effects on the production of biomass, biochemical composition and antioxidant capacity
Článek Constitutive expression of an A-5 subgroup member in the DREB transcription factor subfamily from Ammopiptanthus mongolicus enhanced abiotic stress tolerance and anthocyanin accumulation in transgenic Arabidopsis
Článek Stable carbon isotope diagnostics of mammalian metabolism, a high-resolution isotomics approach using amino acid carboxyl groups
Článek Factors associated with depressive symptoms in patients with ankylosing spondylitis in Northern Taiwan
Článek Retraction: Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1
Článek Potential role for microRNA-16 (miR-16) and microRNA-93 (miR-93) in diagnosis and prediction of disease progression in mycosis fungoides in Egyptian patients
Článek Rapid visual categorization is not guided by early salience-based selection
Článek Relative contribution of climate and non-climate drivers in determining dynamic rates of boreal birds at the edge of their range
Článek A simple-to-use nomogram to predict long term survival of patients undergoing coronary artery bypass grafting (CABG) using bilateral internal thoracic artery grafting technique
Článek Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model
Článek Antenatal and intrapartum interventions for reducing caesarean section, promoting vaginal birth, and reducing fear of childbirth: An overview of systematic reviews
Článek Relative species abundance successfully predicts nestedness and interaction frequency of monthly pollination networks in an alpine meadow
Článek Correction: RCER: Reliable Cluster-based Energy-aware Routing protocol for heterogeneous Wireless Sensor Networks
Článek Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
Článek Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV
Článek Application of national pollutant inventories for monitoring trends on dioxin emissions from stationary industrial sources in Australia, Canada and European Union
Článek Retraction: Interleukin-1β-Induced Autophagy-Related Gene 5 Regulates Proliferation of Embryonic Stem Cell-Derived Odontoblastic Cells
Článek A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique
Článek E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
Článek “You’re kind of at war with yourself as a nurse”: Perspectives of inpatient nurses on treating people who present with a comorbid opioid use disorder
Článek A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury
Článek Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight
Článek Understanding fatigue in adults with visual impairment: A path analysis study of sociodemographic, psychological and health-related factors
Článek Retraction: Mouse-Induced Pluripotent Stem Cells Differentiate into Odontoblast-Like Cells with Induction of Altered Adhesive and Migratory Phenotype of Integrin
Článek A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve
Článek The cause of anorexia and proportion of its recovery in older adults without underlying disease: Results of a retrospective study
Článek Referral and admission to intensive care: A qualitative study of doctors’ practices in a Tanzanian university hospital
Článek Agreement between clinical and non-clinical digital manometer for assessing maximal respiratory pressures in healthy subjects
Článek Heads or tails? Differential translational regulation in cercarial heads and tails of schistosome worms
Článek Horizontal seed dispersal by dung beetles reduced seed and seedling clumping, but did not increase short-term seedling establishment
Článek Shoulder girdle injuries involving the medial clavicle differ from lateral clavicle injuries with a focus on concomitant injuries and management strategies: A retrospective study based on nationwide routine data
Článek Unraveling middle childhood attachment-related behavior sequences using a micro-coding approach
Článek Divergence history and hydrothermal vent adaptation of decapod crustaceans: A mitogenomic perspective
Článek Duration of solid fuel cookstove use is associated with increased risk of acute lower respiratory infection among children under six months in rural central India
Článek Evolving flocking in embodied agents based on local and global application of Reynolds’ rules
Článek Non-invasive contrast enhanced ultrasound molecular imaging of inflammation in autoimmune myocarditis for prediction of left ventricular fibrosis and remodeling
Článek Association between socioeconomic status and diet quality in Mexican men and women: A cross-sectional study
Článek Is Betula carpatica genetically distinctive? A morphometric, cytometric and molecular study of birches in the Bohemian Massif with a focus on Carpathian birch
Článek Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance
Článek The genome of the migratory nematode, Radopholus similis, reveals signatures of close association to the sedentary cyst nematodes
Článek Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR
Článek Overlap between telangiectasia and photoreceptor loss increases with progression of macular telangiectasia type 2
Článek The role of hope for health professionals in rehabilitation: A qualitative study on unfavorable prognosis communication
Článek Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression
Článek Molecular characterization and In Vitro synthesis of infectious RNA of a Turnip vein-clearing virus isolated from Alliaria petiolata in Hungary
Článek Assessment of client satisfaction with pharmacist services at outpatient pharmacy of Tikur Anbessa Specialized Hospital
Článek Thermogravimetric analysis of the co-combustion of coal and polyvinyl chloride
Článek Roles of leptin in the recovery of muscle and bone by reloading after mechanical unloading in high fat diet-fed obese mice
Článek Unexpected high seroprevalence of hepatitis E virus in patients with alcohol-related cirrhosis
Článek APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy
Článek Integrating a gait analysis test in hospital rehabilitation: A service design approach
Článek Correction: Bioactivity-guided isolation of rosmarinic acid as the principle bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum
Článek Soil-borne fungi influence seed germination and mortality, with implications for coexistence of desert winter annual plants
Článek Applying Corrigan’s progressive model of self-stigma to people with depression
Článek Do psychosocial factors modify the negative association between disability and life satisfaction in old age?
Článek Transcriptional foliar profile of the C3-CAM bromeliad Guzmania monostachia
Článek Application of tuned liquid column ball damper (TLCBD) for improved vibration control performance of multi-storey structure
Článek Do protection gradients explain patterns in herbivore densities? An example with ungulates in Zambia’s Luangwa Valley
Článek Consequences of chronic bacterial infection in Drosophila melanogaster
Článek The effects of environmental parameters on the microbial activity in peat-bog lakes
Článek Differences in protein structural regions that impact functional specificity in GT2 family β-glucan synthases
Článek Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan
Článek Changes of absorbed dose rate in air in metropolitan Tokyo relating to radiocesium released from the Fukushima Daiichi Nuclear Power Plant accident: Results of a five-year study
Článek Histological chorioamnionitis, antenatal steroids, and neonatal outcomes in very low birth weight infants: A nationwide study
Článek A machine learning approach for the prediction of pulmonary hypertension
Článek Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal disease
Článek Impaired processing of threat in psychopathy: A systematic review and meta-analysis of factorial data in male offender populations
Článek Dimethyl disulfide (DMDS) as an effective soil fumigant against nematodes in China
Článek Risk factors for hepatitis C infection among adult patients in Kedah state, Malaysia: A case–control study
Článek Factoring a 2 x 2 contingency table
Článek The development of connectives in three to five-year-old monolingual Spanish-speaking children
Článek Foliar plasticity related to gradients of heat and drought stress across crown orientations in three Mediterranean Quercus species
Článek The evolution of haploid chromosome numbers in Meliponini
Článek Bloodstream infections caused by Escherichia coli in onco-haematological patients: Risk factors and mortality in an Italian prospective survey
Článek Facial features and unethical behavior – Doped athletes show higher facial width-to-height ratios than non-doping sanctioned athletes
Článek Non-resolution of non-alcoholic fatty liver disease (NAFLD) among urban, adult Sri Lankans in the general population: A prospective, cohort follow-up study
Článek Are we ready for scaling up restoration actions? An insight from Mediterranean macroalgal canopies
Článek Age-related changes in size, bone microarchitecture and volumetric bone mineral density of the mandible in the harbor seal (Phoca vitulina)
Článek Parasitism modifies the direct effects of warming on a hemiparasite and its host
Článek Transcript profile of skeletal muscle lipid metabolism genes affected by diet in a piglet model of low birth weight
Článek Differential impact of smoking on cardiac or non-cardiac death according to age
Článek Influence of injectate volume on paravertebral spread in erector spinae plane block: An endoscopic and anatomical evaluation
Článek Correction: Nitrogen starvation induces distinct photosynthetic responses and recovery dynamics in diatoms and prasinophytes
Článek Healthcare needs and programmatic gaps in transition from pediatric to adult care of vertically transmitted HIV infected adolescents in India
Článek Retraction: Neuronal Differentiation Dictates Estrogen-Dependent Survival and ERK1/2 Kinetic by Means of Caveolin-1
Článek Correction: Disability and its association with sociodemographic factors among elderly persons residing in an urban resettlement colony, New Delhi, India
Článek Antibacterial activity of varying UMF-graded Manuka honeys
Článek Correction: Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli
Článek Detection and genetic characterization of Echinococcus granulosus mitochondrial DNA in serum and formalin-fixed paraffin embedded cyst tissue samples of cystic echinococcosis patients
Článek Deep-learning-based risk stratification for mortality of patients with acute myocardial infarction
Článek Links between meaning in life and physical quality of life after rehabilitation: Mediating effects of positive experiences with physical exercises and mobility
Článek The estrogen effect; clinical and histopathological evidence of dichotomous influences in dogs with spontaneous mammary carcinomas
Článek The association between socioeconomic status, psychopathological symptom burden in mothers, and early childhood caries of their children
Článek Increased rate of FEV1 decline in HIV patients despite effective treatment with HAART
Článek Parallels between stream and coastal water quality associated with groundwater discharge
Článek Shift in trophic niches of soil microarthropods with conversion of tropical rainforest into plantations as indicated by stable isotopes (15N, 13C)
Článek On the development of sleep states in the first weeks of life
Článek CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro
Článek Investigation into pathophysiology of naturally occurring palatal instability and intermittent dorsal displacement of the soft palate (DDSP) in racehorses: Thyro-hyoid muscles fatigue during exercise
Článek Correction: Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts
Článek MitoToxy assay: A novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic
Článek Correction: Evidence for plant-derived xenomiRs based on a large-scale analysis of public small RNA sequencing data from human samples
Článek Correction: Prognostic impact of systolic blood pressure variability in people with diabetes
Článek Retraction: Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis
Článek Too much? Mortality and health service utilisation among Danish children 1999-2016: A register-based study
Článek Effects of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on diabetic retinopathy and its progression: A real-world Korean study
Článek Genetic codes optimized as a traveling salesman problem
Článek Using family network data in child protection services
Článek Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials
Článek Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study
Článek Stated-preference research in HIV: A scoping review
Článek Correction: Survival of infants ≤24 months of age with brain tumors: A population-based study using the SEER database
Článek Antinociceptive compounds and LC-DAD-ESIMSn profile from Dictyoloma vandellianum leaves
Článek Prevalence and predictors of primary postpartum hemorrhage: An implication for designing effective intervention at selected hospitals, Southern Ethiopia
Článek Correction: Stillbirths in urban Guinea-Bissau: A hospital- and community-based study
Článek Correction: Method for spike detection from microelectrode array recordings contaminated by artifacts of simultaneous two-photon imaging
Článek Correction: Peripheral blood mononuclear cells extracts VEGF protein levels and VEGF mRNA: Associations with inflammatory molecules in a healthy population
Článek Correction: Novel site-specific PEGylated L-asparaginase
Článek Effect of caffeine ingestion on competitive rifle shooting performance
Článek Correction: Color adaptation induced from linguistic description of color
Článek Correction: A biface production older than 600 ka ago at Notarchirico (Southern Italy) contribution to understanding early Acheulean cognition and skills in Europe
Článek Correction: A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing
Článek Correction: Relationship between non-communicable diseases and background characteristics among homeless people in Nagoya City, Japan
Článek Correction: Frozen by stress: Stress increases scope insensitivity
Článek The pragmatic role of trust in young children’s interpretation of unfamiliar signals
Článek Correction: Forecasting the impact of population ageing on tuberculosis incidence
Článek “The car is my extra legs” – Experiences of outdoor mobility amongst immigrants in Sweden with late effects of polio
Článek Correction: Multilevel analyses of on-demand medication data, with an application to the treatment of Female Sexual Interest/Arousal Disorder
Článek Correction: The world’s user-generated road map is more than 80% complete
Článek Correction: Predictors of opioid efficacy in patients with chronic pain: A prospective multicenter observational cohort study
Článek Correction: Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public hospital
Článek Correction: Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases
Článek Correction: Effect of early measles vaccine on pneumococcal colonization: A randomized trial from Guinea-Bissau
Článek Correction: Tuberculosis patients in an Indian mega-city: Where do they live and where are they diagnosed?
Článek Correction: Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma
Článek Correction: A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas
Článek Correction: Evolution and study of a copycat effect in intimate partner homicides: A lesson from Spanish femicides
Článek Correction: Transforming growth factor beta 1 induces methylation changes in lung fibroblasts
Článek Correction: Congenital Zika Syndrome in a Brazil-Paraguay-Bolivia border region: Clinical features of cases diagnosed between 2015 and 2018
Článek Correction: Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
Článek Correction: Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
Článek Correction: Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight
Článek Retraction: Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery
Článek Retraction: Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells
Článek Phenotypic determinism and contingency in the evolution of hypothetical tree-like organisms
Článek Characterising the harmonic vocal repertoire of the Indian wolf (Canis lupus pallipes)
Článek Neural, functional, and aesthetic impacts of spatially heterogeneous flicker: A potential role of natural flicker
Článek Differentiating electrophysiological indices of internal and external performance monitoring: Relationship with perfectionism and locus of control
Článek Time series analysis and forecasting with ECOTOOL
Článek Incorporating evaporative water loss into bioenergetic models of hibernation to test for relative influence of host and pathogen traits on white-nose syndrome
Článek Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences
Článek Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways
Článek Elucidating optical field directed hierarchical self-assembly of homogenous versus heterogeneous nanoclusters with femtosecond optical tweezers
Článek Comparison of HIV-1 Vif and Vpu accessory proteins for delivery of polyepitope constructs harboring Nef, Gp160 and P24 using various cell penetrating peptides
Článek Isolation and characterization of five novel probiotic strains from Korean infant and children faeces
Článek Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice
Článek Election forensics: Using machine learning and synthetic data for possible election anomaly detection
Článek Recommendation system in social networks with topical attention and probabilistic matrix factorization
Článek Visualizing a field of research: A methodology of systematic scientometric reviews
Článek BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss
Článek Tick-borne encephalitis virus infections in Germany. Seasonality and in-year patterns. A retrospective analysis from 2001-2018
Článek Typological analysis of public-private partnerships in the veterinary domain
Článek Green synthesis of silver nanoparticles using Solanum mammosum L. (Solanaceae) fruit extract and their larvicidal activity against Aedes aegypti L. (Diptera: Culicidae)
Článek Evaluating case management as a complex intervention: Lessons for the future
Článek Has the “M” word been framed? Marijuana, cannabis, and public opinion
Článek A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period
Článek The association between vaccination confidence, vaccination behavior, and willingness to recommend vaccines among Finnish healthcare workers
Článek The coupling of the M2 muscarinic receptor to its G protein is voltage dependent
Článek Subsidy strategy of pharmaceutical e-commerce platform based on two-sided market theory
Článek Care coordination for chronic and complex health conditions: An experienced based co-design study engaging consumer and clinician groups for service improvement
Článek Surveillance of panicle positions by unmanned aerial vehicle to reveal morphological features of rice
Článek Public perception of coastal habitat loss and habitat creation using artificial floating islands in the UK
Článek Left ventricular simulation of cardiac compression: Hemodynamics and regional mechanics
Článek Analytic performance of PANArray HPV and HPV 9G DNA chip tests for genotyping of high-risk human papillomavirus in cervical ThinPrep PreservCyt samples
Článek Determinants of anemia among pregnant women attending antenatal care in Horo Guduru Wollega Zone, West Ethiopia: Unmatched case-control study
Článek Depression and anxiety among pregnant women living with HIV in Kilimanjaro region, Tanzania
Článek Shipworm bioerosion of lithic substrates in a freshwater setting, Abatan River, Philippines: Ichnologic, paleoenvironmental and biogeomorphical implications
Článek Effect of antenatal detection of small-for-gestational-age newborns in a risk stratified retrospective cohort
Článek Transcriptome sequencing reveals the effect of biochar improvement on the development of tobacco plants before and after topping
Článek Time series experimental design under one-shot sampling: The importance of condition diversity
Článek Evaluation of protocols for rRNA depletion-based RNA sequencing of nanogram inputs of mammalian total RNA
Článek MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity
Článek Measurement of horizontal ocular deviation on magnetic resonance imaging in various disease with acute vertigo
Článek Clinical outcomes of early gastric cancer with non-curative resection after pathological evaluation based on the expanded criteria
Článek Detection of quantitative trait loci associated with drought tolerance in St. Augustinegrass
Článek An examination of the Kuleshov effect using still photographs
Článek An exploration of automated narrative analysis via machine learning
Článek Measuring egocentric distance perception in virtual reality: Influence of methodologies, locomotion and translation gains
Článek Mathematical modeling of cardiac function to evaluate clinical cases in adults and children
Článek Correction: Priority Queue Based Reactive Buffer Management Policy for Delay Tolerant Network under City Based Environments
Článek Correction: Isolation of five Enterobacteriaceae species harbouring blaNDM-1 and mcr-1 plasmids from a single paediatric patient
Článek Correction: Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents
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PLOS One

2019 Číslo 10
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Autori: MUDr. Tomáš Ürge, PhD.
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