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Can they imagine the future? A qualitative study exploring the skills employers seek in pharmaceutical sciences doctoral graduates
Authors: Jacqueline E. McLaughlin aff001; Lana M. Minshew aff001; Daniel Gonzalez aff002; Kelsey Lamb aff003; Nicholas J. Klus aff003; Jeffrey Aubé aff004; Wendy Cox aff005; Kim L. R. Brouwer aff002
Authors place of work: Center for Innovative Pharmacy Education and Research, Division of Practice Advancement and Clinical Education, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina, United States of America aff001; Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina, United States of America aff002; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina, United States of America aff003; Division of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina, United States of America aff004; Division of Practice Advancement and Clinical Education, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, North Carolina, United States of America aff005
Published in the journal: PLoS ONE 14(9)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0222422Summary
Concerns about the extent to which graduate programs adequately prepare students for the workplace have prompted numerous calls for reform. Understanding what employers look for in doctoral graduates can help schools better align graduate training with workplace needs. Twelve pharmaceutical scientists across diverse specialties and career pathways described the skills considered requisite for success in today’s science economy. Depth and breadth of knowledge, communication, collaboration, adaptability, research productivity, experiential training, and motivation and drive were among the themes identified. These results can be used to inform the development of doctoral curricula in the biomedical sciences.
Keywords:
Social sciences – Sociology – Communications – Social communication – People and places – Population groupings – Medicine and health sciences – Economics – pharmacology – Drug research and development – Labor economics – Employment – Jobs – Education – Schools – Educational status – Graduates – Careers – Drug discovery
Introduction
Career pathways in the pharmaceutical sciences are increasingly diverse, in part due to changing workforce needs and evolving student interests. In academia, for example, the number of biomedical doctorate recipients has increased significantly as the number of available tenure-track academic positions has declined [1, 2]. There is approximately one tenure-track position in the United States for every 6.3 Doctor of Philosophy (PhD) graduates, which means that more than 80% of new biomedical graduates are pursuing careers outside of academia [3]. Furthermore, graduate interest in tenure-track faculty positions often drops over the course of a PhD program [4]. As a result, more graduates are now pursuing alternative career pathways such as jobs in the private sector at established and startup pharmaceutical, biotechnology or biomedical research-related companies, research institutes, government regulatory agencies, non-profit organizations and non-research focused positions [4, 5].
The evolution of career pathways is further influenced by recent and rapid advancements in science. New technologies, techniques, materials, processes, and regulations can influence what types of jobs are available and what skills are needed in the workforce. In the pharmaceutical sciences, for example, rapid growth in the application of mathematical modeling and simulation in drug discovery and development has significantly increased the demand for well-trained and experienced quantitative scientists [6]. The application of artificial intelligence at all stages of drug discovery and development—from data mining and assistance in target identification and validation, to lead compound selection and prediction of drug candidate properties and risks–requires knowledgeable, “next generation” pharmaceutical scientists. Advances in gene editing, immuno-oncology, the role of the microbiome in disease pathogenesis and treatment, and precision medicine necessitate a scientific workforce with broad training in the chemical, biological and translational sciences in addition to scientific expertise in specific areas of the pharmaceutical sciences. In addition, there is a need for scientists who compare the effectiveness of available medications used to treat the same condition; evaluate implementation of new interventions and approaches to improve access to effective medications; and conduct pharmaceutical policy analyses.
Despite these changes, graduate training in the biomedical sciences remains largely unchanged. Doctoral students in the United States typically spend approximately 1 to 2 years taking coursework and complete 3 to 5 years of research under the close guidance of a faculty member. While digital age advancements are evident, such as improved access to published information and on-demand training, these advances have had little impact on the basic structure of graduate training and mentoring. The student-faculty apprenticeship model relies heavily on the knowledge, perspective, and quality of faculty mentors, and results in widely variable training experiences for students. Since many faculty have limited experience in careers outside of academia [7], they may be ill-equipped to provide guidance about non-academic careers [8] and subsequently encourage students to pursue tenure-track academic careers [4]. This disconnect can result in a significant gap in the support provided to, and the development of, those students who are considering non-academic positions [9].
Concerns about the extent to which graduate programs adequately prepare scientists for the workplace have prompted numerous calls for reform. Doctoral graduates often struggle to align their highly specialized knowledge and skills with the needs of employers while companies criticize the shortage of adequately prepared prospects [10]. Although a growing number of advocates propose rethinking doctoral training in an effort to better prepare graduates for success [1, 9, 11, 12, 13], few studies clearly identify the specific skills required by graduates in today’s rapidly evolving pharmaceutical industries. In the pharmaceutical sciences, most draw from faculty perspectives or literature reviews to identify core skills for graduate training. Wu Pong and colleagues [14], for example, synthesized literature to identify skills needed in the pharmaceutical industry, which included flexibility, creativity, leadership, communication, proposal writing, mentoring, business skills, and collaboration. More recently, the 2016–2017 Research and Graduate Affairs Committee of the American Association of Colleges of Pharmacy arrived at six domains of core competencies for graduate training in the pharmaceutical sciences: foundational knowledge, research, scientific communication, education, leadership and management, and personal and professional development [15].
Amid recent economic, professional, and technical changes, more research is necessary to better understand what skills graduates need to be competitive on the job market and advance the pharmaceutical sciences [14]. Inquiring directly with employers to explore how graduate programs can better support the development of key skills and abilities in graduates is an important step for aligning graduate training with workplace needs. The goal was to identify core skills that employers look for when hiring doctoral graduates from the pharmaceutical sciences.
Methods
In March, 2017, the UNC Eshelman School of Pharmacy charged a committee with re-envisioning graduate education in the pharmaceutical sciences, which would provide the foundation for transformation of our pharmaceutical sciences graduate program. The committee consisted of 10 faculty members representing each of the School’s five divisions, two doctoral students, a staff member from the Office of Curricular and Student Affairs, and a health sciences librarian. As part of its charge to rethink the doctoral curricula at the School, the committee decided to interview experts across various sectors of pharmaceutical sciences in order to better understand the contemporary landscape of the pharmaceutical sciences discipline and the skills graduates needed to be successful within that landscape.
Participants
Interviews were conducted in November and December 2017 with 12 identified experts representing expertise across all five academic divisions at the School: Chemical Biology and Medicinal Chemistry; Pharmacoengineering and Molecular Pharmaceutics; Pharmacotherapy and Experimental Therapeutics; Practice Advancement and Clinical Education; and Pharmaceutical Outcomes and Policy. At least 2 experts were identified and recommended by members of each academic division, ensuring that responses reflected the various areas of the pharmaceutical sciences. Eight experts were external to the School and four held positions within academia. In addition, pharmaceutical scientists with diverse expertise, career paths and current positions were interviewed, including global pharmaceutical companies, small start-up companies, government, and academia. Each participant was contacted via email and invited to participate in a 60-minute interview. Twelve out of 14 invited experts agreed to participate (85.7% response rate).
Data collection
Each expert received information about the purpose of the interview, along with the interview questions prior to the interview. Interviews were conducted either in person or synchronously via Zoom [San Jose, CA] depending on the expert’s availability. All interviews were recorded and transcribed verbatim for analysis purposes. All members of the committee were invited to attend the interviews. Interviews were semi-scripted, with three primary areas of inquiry: changes in drug discovery, development and evaluation and its effect on graduate student training; important graduate student attributes; and ideas for graduate training. Additional probing questions were asked by committee members, as needed, to clarify or facilitate further discussion with the expert [See Appendix].
Data analysis
The analysis focused on a single research question: What do graduates of our Pharmaceutical Sciences PhD programs need to be able to do/demonstrate to be successful? Grounded theory shaped the coding and analysis process [16]; six members of the committee volunteered to serve as data analysts and were responsible for open coding four of the 12 interviews for attributes, skills, and abilities described by the experts. Data analysts were assigned interview transcripts that were not in their area of expertise, and each interview transcript had at least two coders from different academic divisions. Each person was provided a guiding document and instructions on how to open code an interview transcript. After reading through the interview transcript, analysts were asked to note important statements that focused on the skills future graduates from the pharmaceutical sciences would need. Next, analysts were instructed to create a code descriptor along with an example quote from the transcript to illustrate their code.
Once all transcripts were open coded, one committee member (JM) compiled the initial coding from all transcripts to synthesize the data and identify emerging themes. Seven themes emerged through the initial review process. These themes were presented along with relevant quotes from the interviews to the research team for review; the team discussed any discrepancies or disagreements. Following this consensus building, results also were shared with School faculty during a retreat for questions and feedback. An independent qualitative analysis expert (LM) coded the transcripts following these processes. The inter-rater reliability for the thematic analysis coding was 0.99 with a 95% confidence interval, suggesting that there was excellent inter-rater reliability between the coders. These qualitative research steps (i.e., multiple coders, peer-debriefing, member-checking) promote trustworthiness of the findings.
Ethical considerations, consent
This project was submitted to the UNC Institutional Review Board and processed under case number 18–0275. The submission was reviewed by the Office of Human Research Ethics, which determined it did not constitute human subjects research as defined under United States federal regulations [45CFR 46.102 (d or f) and 21 CFR 56.102(c)(e)(l)] and did not require IRB approval. Although consent was not required, all interviewees were informed of the purpose of the interviews (i.e. program evaluation and improvement, aimed at informing the revision of the School’s graduate program) during the recruitment phase and again at the start of the interview and all agreed before starting the interview.
Results
The thematic analysis revealed seven broad themes about the skills and abilities employers look for when hiring pharmaceutical sciences doctoral graduates. Four of the themes were expressed by all 12 experts: knowledge, communication, collaboration, and motivation and curiosity. Three themes were salient, yet not present in every interview: adaptability, experiential training, as well as critical thinking and problem solving. In addition, ideas provided by participants for better aligning graduate training programs with workforce needs were compiled. Descriptions of each theme are presented below and in Table 1, along with relevant example quotes. While the overarching themes emerged as distinct from one another, they were not always mutually exclusive, and some quotes occasionally overlapped multiple themes. For example, some comments about communication overlapped with collaboration since communication is an inherent aspect of working with others.
Tab. 1. Themes and summary descriptions of skills employers seek in pharmaceutical science doctoral graduates.
Knowledge
Every expert identified knowledge, in some capacity, as critical in prospective employees. The experts discussed knowledge in terms of depth and breadth, research achievements, and an individual’s familiarity with new and emerging methods. One expert stated, “Above everything, I look for people who have good, good, solid, scientific training, background, and understanding… they’re going to have to really show, at least for their area, [that] they have depth of knowledge.” Another expert echoed this sentiment by stating, “there is an aspect of depth, so the assumption is you have depth in some things and if you look at those that are successful they have a deep understanding.”
While depth was considered necessary, it was not considered sufficient. Experts wanted individuals who also had a breadth of knowledge across various areas, demonstrating their intellectual diversity. For example, one expert stated, “we’re really looking for diversity of thought,” while another stated, “I like to have it both ways in the sense that we do like people to bring in an area of specialization, that may be cutting edge, may help to push us to the vanguard of an area, but our work in general is very broad.”
In addition to depth and breadth of knowledge, experts discussed knowledge related to research. Six of the experts specifically referenced scholarly publications as an important achievement and indicator of knowledge and knowledge-based ability. For instance, one expert stated, “I would also say publications are pretty important …it’s unfortunate, sort of superficial in a way, but we do definitely look for those [individuals] that have very high-profile publications.” Experts indicated that the number and type of publications, along with the journals they are published in are held in high regard when considering a recent graduate for employment.
Finally, graduate students’ knowledge about new and emerging methods was considered high priority. Areas mentioned during interviews included bio-informatics, chem-informatics, translational sciences, and the use of big data and data science. Experts also emphasized that the field of pharmaceutical sciences is changing. One expert said, “I feel like we’re entering another phase of the information age, so really big data and data science it’s an emerging field. We’re flooded with many sources of data and to be able to analyze that data, that involves computer and software skills.” Still another expert identified other methodological changes that need attention for chemistry-oriented applicants when they said, “You don’t see a lot of total synthesis anymore, so we look more at methodology. If I’m looking at somebody to do chemical biology work, we would look more for somebody perhaps with more of a mix of a little bit of synthetic-organic chemistry, but a bit more biochemistry and some experience that could apply to the chemical biology work.” Here the experts acknowledged that the industry is changing and pharmaceutical sciences graduates must be equipped with knowledge that is contemporary and relevant to emerging areas of science.
Communication
Experts indicated that graduates need to be able to communicate in verbal and written form while also demonstrating the ability to listen. Many experts indicated that “being able to translate your work” so that a variety of people could understand it was essential. Experts noted the increasingly interdisciplinary nature of the pharmaceutical sciences and the expectation that scientists communicate effectively and efficiently across various contexts and audiences. One expert noted, “there’s a different level of communication, when you are talking to another scientist versus when you’re talking to a patient or you’re talking to a clinician.” More specifically, “the ability to really hone down on what’s important and present it [the research] in a way so that someone who is intelligent but not a subject area expert could understand and really understand the impact.” Said more simply, “Can you listen to people and can you get your point across?”
Although verbal communication was a major focus, experts also identified strong written communication as a necessity. As noted by one participant, “I see abstracts from individuals who I know are very smart, but I have no idea what they’re trying to communicate to me.” Several experts also noted deficits in written communication, with one expert stating, “well, writing is a lost art” and another, “I see more challenges with written communication than oral” indicating that strong written communication could be a skill that differentiates new graduates.
Collaboration
Comments about communication often were coupled with those emphasizing collaboration. Every expert expressed the need for pharmaceutical sciences graduates to possess the ability to collaborate with others, using terms such as teamwork, groups, multidisciplinary, fit, shared goals, and cross-divisional. One expert stated, “the first thing that I look for is for people who can work in teams, very important in the industry.” Discussions regarding collaboration indicated that graduate students needed to demonstrate their ability to work productively with others, whether those individuals were in their lab setting or in an interdisciplinary setting. One expert noted looking for graduates that “understand how they fit within that team, when it’s appropriate for them to speak up, the type of information for them to communicate…”
Motivation and curiosity
This theme is unique in that every expert mentioned this element, yet described it using different terms and descriptions. Some called it “curiosity,” “innovation,” “that extra little spark,” “driven,” or “ability to grow professionally.” Despite these variations, all experts spoke to an innate element of an individual that set them apart from others. The experts were looking for individuals who would thrive under pressure, be able to anticipate change, and create or identify opportunity. One expert described it as they “come with a different mindset” while another noted, “we are looking for people that are forward thinking…that will take on responsibility to educate themselves.” Another expert expressed, “I look for fire in the belly. Are they excited? Can they imagine the future?” Although, the experts described this quality in different ways, all descriptions reflected upon an individual’s potential to be successful in a variety of capacities within the workplace.
Adaptability
Experts identified adaptability as another important trait for graduate students to possess, with one expert noting, “the nature of the drug discovery business is always changing, so you just have to hire smart people who are adaptable, who are open to learning, learning new skills.” This statement suggests that graduates cannot remain stagnant with the skills they obtain during their graduate studies. To remain competitive, they will need to keep pace with the rapid growth and changes in the pharmaceutical sciences. Additionally, the experts expressed that graduates need to convey a desire to grow, be “flexible and resilient”, and welcome challenges in their work.
Experiential training
Experts suggested that graduates with experience in more “real-world application” and stronger networks within the pharmaceutical sciences were often more competitive applicants. As noted by one, “It’s not totally where you come from and what you know, it’s who you know.” Another acknowledged real world experience as nearly universal in their new hires, “A lot, if not all, of the individuals we bring in…have had some background doing a project within the industry.” Several suggested that pharmaceutical sciences programs should implement “short-term rotations…to just get a sense of what [industry is] like,” which would “allow the individual to come in, get an understanding of how the industry works, and get an understanding of what kind of science is being done and how that person can integrate themselves into that type of science.” This suggests that experiential training during graduate school would be beneficial for both the student and the future employer.
Critical thinking and problem solving
The final theme focused on the ability of graduate students to work through difficult problems. Experts indicated that graduate students must be able to work through problems on their own while also knowing when to seek help. As one expert stated, “what I’m really looking for is how do people approach the problem that they had? What did they contribute to solving that problem? How they went about solving the problem, and what they delivered at the end.” Relatedly, experts highlighted strong research skills as a core component of problem solving and agreed that the ability to demonstrate strong analysis skills can set graduates apart from other applicants. As noted by one expert, “Once they’ve done an experiment or analysis, how do they put the information together to really link it back to the question that they were supposed to be addressing in the beginning?”
Improving graduate training
Participants provided numerous suggestions for improving graduate training, aimed at better preparing graduates for success in the workplace and aligning graduate programs with the needs of the workforce. Engaging students in more situated learning with hands-on experience was a common suggestion. As suggested by participants: “the last three years need to be 90%, or more, hands-on in the lab research;”
“build in team-based projects where everybody has to pull their weight and figure out how to interface to achieve a common goal;” and “allow the graduate student to spend some time with either a research lab or our organization.” In addition, participants encouraged the integration of more training in communication: “Teaching individuals how to write a good abstract is a very good exercise.” and “if [graduates] are going to have to work with other people who don't have their background then I think it's very important to learn to work with and communicate [with] them while you're in a PhD program.” Lastly, several participants noted that while health care has changed, “health care will continue to dramatically change, based on finances, based on the economy, based on a lot of different factors”, highlighting the need for ongoing evaluation and revision of graduate training programs to ensure that they remain contemporary and relevant.
Discussion
Graduate programs must equip students with the skills most valued and needed by the marketplace [14, 17]. This is a unique challenge in today’s science economy amid technological advancements, diversifying career pathways, and shifting student interests. As doctoral graduates oversaturate the academic job market [1, 2], graduate programs must position students to develop skills that both differentiate them and meet workforce needs.
This work provides insight into what employers seek in doctoral graduates within the rapidly evolving world of the pharmaceutical sciences. Our results align closely with literature describing skills considered necessary for success across other industries, such as Tony Wagner’s New World of Work and the Seven Survival Skills [18]. Wagner identified seven core skills: critical thinking and problem solving, collaboration across networks and leading by influence; agility and adaptability; effective oral and written communication; initiative and entrepreneurialism; accessing and analyzing information; and curiosity and imagination [18]. More specifically, our results align with literature reviews and faculty commentaries in the pharmaceutical sciences concerning core skills, such as foundational knowledge, flexibility, creativity, communication, collaboration, and research [14, 15]. Our experts’ emphasis on breadth of knowledge, experiential training, and research productivity may help graduate programs better understand needs of the job market and, subsequently, the needs of students preparing for that market.
Identifying strategies that optimize student development is imperative for graduate programs aimed at differentiating students. As stated by Wagner, “the most successful companies in the emerging economy need a new and very different kind of worker who teams with others to continuously reinvent the machine as well as the products and services it creates (pg. 41)” [18]. How can graduate programs help students develop skills and abilities that differentiate them in a competitive job market? Furthermore, how can programs achieve this aim for multiple, diverse career pathways within a single curriculum? Our findings suggest that discrete specialization in an area of the pharmaceutical sciences is essential, but no longer sufficient. In addition to depth, graduates need breadth of knowledge, along with the ability to communicate and collaborate across broad audiences and contexts, as pharmaceutical sciences becomes more interdisciplinary.
In addition, lab rotations and experiential training in diverse settings such as industrial or regulatory sectors could provide critical, real-world experience. Our experts stressed a desire for graduate students to have broad professional experiences and exposure to other programs prior to graduation. This might require graduate programs to engage in collaborative communities, not only within and among schools of pharmacy, but through partnerships with industry and government agencies. The Cooperative Research Centres (CRC), for example, have reconceptualized the role and style of doctoral education to support the needs of students amid changing industry needs by providing them with access to training opportunities in a variety of sectors [19, 20]. Students enrolled in the CRC doctoral program often feel better equipped to handle the communication and collaborative demands of jobs in the industrial sector after their workplace experience [19]. As another example, the Centers of Excellence in Regulatory Science and Innovation (CERSI) program provides a formal mechanism to establish collaborations between the U.S. Food and Drug Administration (FDA) and academic institutions (e.g., UCSF-Stanford, Johns-Hopkins). A key expectation is that these centers provide training and professional development opportunities focused on regulatory science, with the help of FDA staff [21].
Further, programs should consider strategies for preparing graduate students for various career pathways, including those outside of academia [9]. Since faculty mentors may not be prepared to provide broad career guidance for jobs outside of academia [7, 22], training and infrastructure may be necessary to support this approach. The NIH Director’s Biomedical Research Workforce Innovation Award: Broadening Experiences in Scientific Training (BEST) (DP7), for example, was created to support institutions whose faculty and staff were working to design and establish new models for training and development programs for biomedical doctoral students [22]. The “Preparing Future Professions” at the University of Kentucky also aims to fill the gap between graduate training and nonacademic career aspirations [23].
An individual’s choice to pursue graduate education in the biomedical sciences can be described by human capital theory [24]. This traditional economic perspective assumes that individuals make decisions by weighing the benefits against the costs for all possible alternatives, and then selecting the best alternative [25, 26]. Benefits for students may include improved likelihood of securing employment that is aligned with their intellectual as well as financial interests. For employers, a graduate degree can signify that the prospective employee is capable of performing the job in question [27, 28, 29], principally improving his or her human capital. However, if our graduate programs fail to equip students with the knowledge and skills needed and valued by employers, the capital associated with a doctoral degree could deteriorate, prompting employers to devalue graduate training.
Calls for reform in the biomedical sciences highlight apparent disconnects between graduate programs and the job market. Advocates have proposed broadening doctoral curricula, for example, to better prepare biomedical PhDs for a wide range of science-related career paths [1, 9, 11, 12]. Others have suggested that the biomedical PhD be restructured into two degrees, one degree geared for academia and a second to train those who would like in-depth science knowledge for use in other careers [11]. Additional recommendations have included the use of master’s degree programs for industry-seeking candidates, limiting the number of individuals who are allowed to pursue a PhD [1, 11, 12], reshaping doctoral training to focus more on critical thinking and scientific rigor [30], and revising current curricula to include more collaborative, personalized, and interdisciplinary work [31]. While most advocate for curricular change, Callier and Vanderford [32] recommend empowering PhD trainees to better understand and navigate the priorities of the academic institutions, stating that “trainees cannot depend on the university to prepare them for their careers; instead, they must take the initiative to research possibilities, create opportunities, and build a career on their own terms.”
Amid these calls for graduate education transformation, this work is a first step toward better understanding what our graduate program must do to better prepare students for the new era of drug discovery and development. Given the importance of this issue, we were surprised by the dearth of research to support evidence-based decision making in graduate education and curriculum design. Additional research is clearly needed to inform the development of graduate curricula that align with market needs, optimize student learning, and promote advancements in science. Exploring the types of activities and strategies used by graduate students to successfully prepare for the job market, for example, could uncover programs, activities, courses, or technologies that could strengthen curricula. Better understanding the needs of faculty mentors as they help prepare graduate students for increasingly diverse employment opportunities could also be critical for positioning our graduate programs for success.
Limitations
There are several limitations to note. First, there was a relatively small sample size. Second, the experts were identified by faculty from a single, yet scientifically-diverse, school. Third, this was limited to experts from the pharmaceutical sciences. While these limitations can constrain generalizability, the methods provided a rich depth of information and promoted trustworthiness of findings. Clear and consistent themes emerged across the interviews, representing expert viewpoints from various career pathways and diverse specializations within the pharmaceutical sciences, which could also be considered relevant for various areas of related science.
Conclusions
The employability of doctoral students is a key concern to educators and employers. To attract and support students in today’s competitive market, doctoral programs must demonstrate to applicants that they will have the qualities and skills most valued by future employers when they graduate [17]. We interviewed experts from various career pathways and pharmaceutical sciences specializations to identify the skills employers seek in prospective employees. Depth and breadth of knowledge, communication, collaboration, and motivation are among the most desirable qualities in the pharmaceutical sciences. These findings have important implications for developing doctoral programs in the pharmaceutical sciences, as well as other biomedical sciences.
Appendix
Interview questions
Changes in Drug Discovery, Development, and Evaluation
- 1
How do you see drug discovery, development and evaluation changing in the next 5–10 years? How does this affect the type of training/skillset that graduate students in pharmaceutical sciences will need to have?
- 2
What do you see as “cutting edge” areas in the pharmaceutical sciences that graduate programs should consider integrating into their training?
Graduate Attributes
- 3
In your experience, what skills does an exemplary graduate of a pharmaceutical sciences program possess?
- 4
What are common deficiencies that you encounter in new graduates with degrees in pharmaceutical sciences?
- 5
What are the most important attributes you look for in hiring, in order, and with relative weight specified?
Graduate Training
- 6
What innovative approaches can graduate training programs use to help graduate students develop “soft skills”?
- 7
Can you think of innovative ways that pharmaceutical companies and/or regulatory agencies can collaborate with academia for graduate training?
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- Correction: Effects of dietary n-6: n-3 polyunsaturated fatty acid ratios on meat quality, carcass characteristics, tissue fatty acid profiles, and expression of lipogenic genes in growing goats
- Speckle tracking derived reference values of myocardial deformation and impact of cardiovascular risk factors – Results from the population-based STAAB cohort study
- Impact of pterygium on the ocular surface and meibomian glands
- Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants
- Transcriptome divergence during leaf development in two contrasting switchgrass (Panicum virgatum L.) cultivars
- Study on Dalfampridine in the treatment of Multiple Sclerosis Mobility Disability: A meta-analysis
- Circulating progenitor cells and the expression of Cxcl12, Cxcr4 and angiopoietin-like 4 during wound healing in the murine ear
- EUSKOR: End-to-end coreference resolution system for Basque
- Inactivating pathogenic bacteria in greywater by biosynthesized Cu/Zn nanoparticles from secondary metabolite of Aspergillus iizukae; optimization, mechanism and techno economic analysis
- Exopolysaccharide producing rhizobacteria and their impact on growth and drought tolerance of wheat grown under rainfed conditions
- Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes
- Correction: Association between ultraviolet radiation exposure dose and cataract in Han people living in China and Taiwan: A cross-sectional study
- Short-term exercise training improves cardiac function associated to a better antioxidant response and lower type 3 iodothyronine deiodinase activity after myocardial infarction
- Unexpected low genetic variation in the South American hystricognath rodent Lagostomus maximus (Rodentia: Chinchillidae)
- PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma
- Surgical resection is sufficient for incidentally discovered solitary pulmonary nodule caused by nontuberculous mycobacteria in asymptomatic patients
- “I do all I can but I still fail them”: Health system barriers to providing Option B+ to pregnant and lactating women in Malawi
- Impact of major illnesses and geographic regions on do-not-resuscitate rate and its potential cost savings in Taiwan
- Implementation of intermittent theta burst stimulation compared to conventional repetitive transcranial magnetic stimulation in patients with treatment resistant depression: A cost analysis
- Genome-wide analysis of DNA methylation profile identifies differentially methylated loci associated with human intervertebral disc degeneration
- Correction: Artificial neural networks reveal individual differences in metacognitive monitoring of memory
- Combining fish and environmental PCR for diagnostics of diseased laboratory zebrafish in recirculating systems
- Reading skill modulates the effect of parafoveal distractors on foveal lexical decision in deaf students
- Association between the posterior part of the circle of Willis and the vertebral artery hypoplasia
- Exposure to marital conflict: Gender differences in internalizing and externalizing problems among children
- Ethanol locks for the prevention of catheter-related infection in patients with central venous catheter: A systematic review and meta-analysis of randomized controlled trials
- The effect of age and perturbation time on online control during rapid pointing
- Oilseed rape (Brassica napus) resistance to growth of Leptosphaeria maculans in leaves of young plants contributes to quantitative resistance in stems of adult plants
- Lymphocyte proliferation induced by high-affinity peptides for HLA-B*51:01 in Behçet’s uveitis
- Sensitization of avian pathogenic Escherichia coli to amoxicillin in vitro and in vivo in the presence of surfactin
- Genomic characterization of the complete terpene synthase gene family from Cannabis sativa
- Inhibition of gap junctional intercellular communication by an anti-migraine agent, flunarizine
- Levels of serum eosinophil cationic protein are associated with hookworm infection and intensity in endemic communities in Ghana
- Plant growth promoting rhizobacterium Stenotrophomonas maltophilia BJ01 augments endurance against N2 starvation by modulating physiology and biochemical activities of Arachis hypogea
- Hierarchical integrated and segregated processing in the functional brain default mode network within attention-deficit/hyperactivity disorder
- Rising co-payments coincide with unwanted effects on continuity of healthcare for patients with schizophrenia in the Netherlands
- Analysis of Zobellella denitrificans ZD1 draft genome: Genes and gene clusters responsible for high polyhydroxybutyrate (PHB) production from glycerol under saline conditions and its CRISPR-Cas system
- False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases
- Identification of potassium phosphite responsive miRNAs and their targets in potato
- Quantification of bell-shaped size selectivity in shrimp trawl fisheries using square mesh panels and a sorting cone after a Nordmøre grid
- Deactivation of somatosensory and visual cortices during vestibular stimulation is associated with older age and poorer balance
- Combined immunization with attenuated live influenza vaccine and chimeric pneumococcal recombinant protein improves the outcome of virus-bacterial infection in mice
- Flooding performance evaluation of alkyl aryl sulfonate in various alkaline environments
- An artificial intelligent diagnostic system on mobile Android terminals for cholelithiasis by lightweight convolutional neural network
- Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads
- COI metabarcoding primer choice affects richness and recovery of indicator taxa in freshwater systems
- Retraction: APRIL Induces Tumorigenesis and Metastasis of Colorectal Cancer Cells via Activation of the PI3K/Akt Pathway
- The intake pattern and feed preference of layer hens selected for high or low feed conversion ratio
- Individualized pattern recognition for detecting mind wandering from EEG during live lectures
- Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison
- Post-activation potentiation effect of eccentric overload and traditional weightlifting exercise on jumping and sprinting performance in male athletes
- Effectiveness of different central venous catheter fixation suture techniques: An in vitro crossover study
- Quantitative detection of ALK fusion breakpoints in plasma cell-free DNA from patients with non-small cell lung cancer using PCR-based target sequencing with a tiling primer set and two-step mapping/alignment
- Nuclei deformation reveals pressure distributions in 3D cell clusters
- Strategies for increasing diagnostic yield of community-onset bacteraemia within the emergency department: A retrospective study
- Rapid evolution of Mexican H7N3 highly pathogenic avian influenza viruses in poultry
- Certified service dogs – A cost-effectiveness analysis appraisal
- Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy
- Assessing the impact of a research funder’s recommendation to consider core outcome sets
- Validity of six consumer-level activity monitors for measuring steps in patients with chronic heart failure
- Detection of deceptive motions in rugby from visual motion cues
- The impact of antenatal care on neonatal mortality in sub-Saharan Africa: A systematic review and meta-analysis
- Epidemiological investigation and management of bloody diarrhea among children in India
- Irisin promotes C2C12 myoblast proliferation via ERK-dependent CCL7 upregulation
- Bacteria isolated from Bengal cat (Felis catus × Prionailurus bengalensis) anal sac secretions produce volatile compounds potentially associated with animal signaling
- Petri net–based model of the human DNA base excision repair pathway
- Complexation and conformation of lead ion with poly-γ-glutamic acid in soluble state
- The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers
- The Youth-Physical Activity Towards Health (Y-PATH) intervention: Results of a 24 month cluster randomised controlled trial
- The COPD multi-dimensional phenotype: A new classification from the STORICO Italian observational study
- Morphological identification of Amphitetranychus species (Acari: Tetranychidae) with crossbreeding, esterase zymograms and DNA barcode data
- Maintaining hope after a disabling stroke: A longitudinal qualitative study of patients’ experiences, views, information needs and approaches towards making treatment decisions
- Cultural differences in the use of acoustic cues for musical emotion experience
- Effects of a rifampicin pre-treatment on linezolid pharmacokinetics
- High prevalence of multidrug resistant Enterobacteriaceae among residents of long term care facilities in Amsterdam, the Netherlands
- Infection/inflammation-associated preterm delivery within 14 days of presentation with symptoms of preterm labour: A multivariate predictive model
- Prognostic value of preoperative hydronephrosis in patients with bladder cancer undergoing radical cystectomy: A meta-analysis
- Correction: Early life predictors of midlife allostatic load: A prospective cohort study
- PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations
- Epstein-Barr virus genome packaging factors accumulate in BMRF1-cores within viral replication compartments
- Symbiotic incompatibility between soybean and Bradyrhizobium arises from one amino acid determinant in soybean Rj2 protein
- Does anticoagulation needed for distally located incidental pulmonary thromboembolism in patients with active cancer?
- Control of human testis-specific gene expression
- Speaking up culture of medical students within an academic teaching hospital: Need of faculty working in patient safety
- Appraisal on the wound healing potential of Melaleuca alternifolia and Rosmarinus officinalis L. essential oil-loaded chitosan topical preparations
- Understanding parental perspectives on outcomes following paediatric encephalitis: A qualitative study
- Results of scoping review do not support mild traumatic brain injury being associated with a high incidence of chronic cognitive impairment: Commentary on McInnes et al. 2017
- Native seed, soil and atmosphere respond to boreal forest topsoil (LFH) storage
- Development of a quantitative polymerase chain reaction assay and environmental DNA sampling methods for Giant Gartersnake (Thamnophis gigas)
- Genetic diversity and population structure of four Chinese rabbit breeds
- Knowledge, attitude and behaviors towards patients with mental illness: Results from a national Lebanese study
- Correction: An impact evaluation of two rounds of mass drug administration on the prevalence of active trachoma: A clustered cross sectional survey
- Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public hospital
- Graph convolutional network approach applied to predict hourly bike-sharing demands considering spatial, temporal, and global effects
- Impact of traffic variability on geographic accessibility to 24/7 emergency healthcare for the urban poor: A GIS study in Dhaka, Bangladesh
- Feeling the heat: Elevated temperature affects male display activity of a lekking grassland bird
- Constructing a comprehensive disaster resilience index: The case of Italy
- Intraocular pressure according to different types of tonometry (non-contact and Goldmann applanation) in patients with different degrees of bilateral tearing
- Prevalent vertebral fracture is dominantly associated with spinal microstructural deterioration rather than bone mineral density in patients with type 2 diabetes mellitus
- Silent volumetric multi-contrast 7 Tesla MRI of ocular tumors using Zero Echo Time imaging
- Nonverbal synchrony in virtual reality
- Do speed cameras reduce road traffic collisions?
- A zero-shot learning approach to the development of brain-computer interfaces for image retrieval
- Use of non-HIV medication among people living with HIV and receiving antiretroviral treatment in Côte d’Ivoire, West Africa: A cross-sectional study
- DNA barcoding of southern African crustaceans reveals a mix of invasive species and potential cryptic diversity
- Development of an international external quality assurance program for HIV-1 incidence using the Limiting Antigen Avidity assay
- Correction: The mean cell volume difference (dMCV) reflects serum hypertonicity in diabetic dogs
- Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6
- Transport oil product consumption and GHG emission reduction potential in China: An electric vehicle-based scenario analysis
- Ontogenetic shift in the energy allocation strategy and physiological condition of larval plaice (Pleuronectes platessa)
- Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
- Diagnostic accuracy of Xpert MTB/RIF assay and non-molecular methods for the diagnosis of tuberculosis lymphadenitis
- Assessment of glucose-6-phosphate dehydrogenase activity using CareStart G6PD rapid diagnostic test and associated genetic variants in Plasmodium vivax malaria endemic setting in Mauritania
- Spatial distribution of breast cancer in Sudan 2010-2016
- Human-induced fire regime shifts during 19th century industrialization: A robust fire regime reconstruction using northern Polish lake sediments
- Enhanced effectiveness of oil dispersants in destabilizing water-in-oil emulsions
- Development of UV spectrophotometry methods for concurrent quantification of amlodipine and celecoxib by manipulation of ratio spectra in pure and pharmaceutical formulation
- Iron and manganese co-limit growth of the Southern Ocean diatom Chaetoceros debilis
- Bilateral and unilateral load-velocity profiling in a machine-based, single-joint, lower body exercise
- Veterans Health Administration nurses’ training and beliefs related to care of patients with traumatic brain injury
- Supplementation strategies affect the feed intake and performance of grazing replacement heifers
- Active transcutaneous bone conduction hearing implants: Systematic review and meta-analysis
- Parameterization-induced uncertainties and impacts of crop management harmonization in a global gridded crop model ensemble
- Acidification effects on isolation of extracellular vesicles from bovine milk
- GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve
- Mining version history to predict the class instability
- Humpback whale song occurrence reflects ecosystem variability in feeding and migratory habitat of the northeast Pacific
- A phase 2 study of an oral mTORC1/mTORC2 kinase inhibitor (CC-223) for non-pancreatic neuroendocrine tumors with or without carcinoid symptoms
- Asprosin response in hypoglycemia is not related to hypoglycemia unawareness but rather to insulin resistance in type 1 diabetes
- Muscle oxygenation maintained during repeated-sprints despite inspiratory muscle loading
- Reconstructing systematic persistent impacts of promotional marketing with empirical nonlinear dynamics
- Trans-national conservation and infrastructure development in the Heart of Borneo
- Prediction of cardiovascular disease risk among people with severe mental illness: A cohort study
- Data in question: A survey of European biobank professionals on ethical, legal and societal challenges of biobank research
- Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers
- Reconstructing birth in Australopithecus sediba
- Value of contrast-enhanced ultrasound for preoperative assessment of liver reserve function in patients with liver tumors
- Correction: Identifying obesity/overweight status in children and adolescents; A cross-sectional medical record review of physicians’ weight screening practice in outpatient clinics, Saudi Arabia
- Incidence and risk factors of loss to follow-up among HIV-infected children in an antiretroviral treatment program
- Changes in intracellular folate metabolism during high-dose methotrexate and Leucovorin rescue therapy in children with acute lymphoblastic leukemia
- Functional role and evolutionary contributions of floral gland morphoanatomy in the Paleotropical genus Acridocarpus (Malpighiaceae)
- On the efficiency of HIV transmission: Insights through discrete time HIV models
- Metabolic cost calculations of gait using musculoskeletal energy models, a comparison study
- Comparison of molecular profile in triple-negative inflammatory and non-inflammatory breast cancer not of mesenchymal stem-like subtype
- Evolutionary analysis of six chloroplast genomes from three Persea americana ecological races: Insights into sequence divergences and phylogenetic relationships
- Cultural transmission in a food preparation task: The role of interactivity, innovation and storytelling
- Correction: Effects of affective priming through music on the use of emotion words
- Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An open-label randomized phase 1 clinical trial
- Estimation of vaccination coverage from electronic healthcare records; methods performance evaluation – A contribution of the ADVANCE-project
- Dietary phytogenics and galactomannan oligosaccharides in low fish meal and fish oil-based diets for European sea bass (Dicentrarchus labrax) juveniles: Effects on gut health and implications on in vivo gut bacterial translocation
- Suicide by hanging: Results from a national survey in Switzerland and its implications for suicide prevention
- Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders
- Genome wide genetic dissection of wheat quality and yield related traits and their relationship with grain shape and size traits in an elite × non-adapted bread wheat cross
- Safety and tolerability of artesunate-amodiaquine, artemether-lumefantrine and quinine plus clindamycin in the treatment of uncomplicated Plasmodium falciparum malaria in Kinshasa, the Democratic Republic of the Congo
- Factors influencing the admission decision for Medical Psychiatry Units: A concept mapping approach
- Comparison of post-traumatic changes in circulating and bone marrow leukocytes between BALB/c and CD-1 mouse strains
- Physiological stress reactivity and recovery related to behavioral traits in dogs (Canis familiaris)
- Associations between birth order with mental wellbeing and psychological distress in midlife: Findings from the 1970 British Cohort Study (BCS70)
- Non-steroidal anti-inflammatory drugs use in older adults decreases risk of Alzheimer’s disease mortality
- The cost-effectiveness of neonatal versus prenatal screening for congenital toxoplasmosis
- Ancient technology and punctuated change: Detecting the emergence of the Edomite Kingdom in the Southern Levant
- Flowers as viral hot spots: Honey bees (Apis mellifera) unevenly deposit viruses across plant species
- Randomized control trial of Tools of the Mind: Marked benefits to kindergarten children and their teachers
- Preserving cultural heritage: Analyzing the antifungal potential of ionic liquids tested in paper restoration
- PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age
- Correction: Unraveling the genetic complexity underlying sorghum response to water availability
- Impact of tear metrics on the reliability of perimetry in patients with dry eye
- Using DNA barcoding to improve invasive pest identification at U.S. ports-of-entry
- Correction: Effects of Lactobacillus plantarum 15-1 and fructooligosaccharides on the response of broilers to pathogenic Escherichia coli O78 challenge
- Physico-chemical characterization and transcriptome analysis of 5-methyltryptophan resistant lines in rice
- Patient factors affecting successful linkage to treatment in a cervical cancer prevention program in Kenya: A prospective cohort study
- Is this a man’s world? The effect of gender diversity and gender equality on firm innovativeness
- Procalcitonin to stop antibiotics after cardiovascular surgery in a pediatric intensive care unit—The PROSACAB study
- Temporal trends, predictors, and outcomes of acute kidney injury and hemodialysis use in acute myocardial infarction-related cardiogenic shock
- Quantitation of free glycation compounds in saliva
- Resolving an 87-year-old taxonomical curiosity with the description of Psylla frodobagginsi sp. nov. (Hemiptera: Sternorrhyncha: Psyllidae), a second distinct Psylla species on the New Zealand endemic plant kōwhai
- The effect of cathodal tDCS on fear extinction: A cross-measures study
- Physiological responses to affiliation during conversation: Comparing neurotypical males and males with Asperger syndrome
- Human cord blood (hCB)-CD34+ humanized mice fail to reject human acute myeloid leukemia cells
- Investigating the dispersal of antibiotic resistance associated genes from manure application to soil and drainage waters in simulated agricultural farmland systems
- Continuous norming of psychometric tests: A simulation study of parametric and semi-parametric approaches
- Phylogenetic microbiota profiling in fecal samples depends on combination of sequencing depth and choice of NGS analysis method
- Cost-effectiveness of apixaban compared to other anticoagulants in patients with atrial fibrillation in the real-world and trial settings
- Biochemical profile and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia
- Low genetic differentiation yet high phenotypic variation in the invasive populations of Spartina alterniflora in Guangxi, China
- A mathematical model for designing networks of C-Reactive Protein point of care testing
- Prevalence of hypochondriac symptoms among health science students in China: A systematic review and meta-analysis
- Femtosecond laser induced step-like structures inside transparent hydrogel due to laser induced threshold reduction
- From In Situ to satellite observations of pelagic Sargassum distribution and aggregation in the Tropical North Atlantic Ocean
- The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology
- BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis
- HIV prevalence and risk behavior among male and female adults screened for enrolment into a vaccine preparedness study in Maputo, Mozambique
- Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients
- Direct estimation of the parameters of a delayed, intermittent activation feedback model of postural sway during quiet standing
- Occurrence mechanism and coping paths of accidents of highly aggregated tourist crowds based on system dynamics
- Correction: Low Dose Aerosol Fitness at the Innate Phase of Murine Infection Better Predicts Virulence amongst Clinical Strains of Mycobacterium tuberculosis
- Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats
- Correction: Public reaction to Chikungunya outbreaks in Italy—Insights from an extensive novel data streams-based structural equation modeling analysis
- Correction: Comparison of neurodegenerative types using different brain MRI analysis metrics in older adults with normal cognition, mild cognitive impairment, and Alzheimer’s dementia
- Intra-individual variability of sleep and nocturnal cardiac autonomic activity in elite female soccer players during an international tournament
- Therapeutic efficacy of equine botulism heptavalent antitoxin against all seven botulinum neurotoxins in symptomatic guinea pigs
- Interleukin 10 knock-down in bovine monocyte-derived macrophages has distinct effects during infection with two divergent strains of Mycobacterium bovis
- Clinical outcomes of bortezomib-based therapy in Taiwanese patients with multiple myeloma: A nationwide population-based study and a single-institute analysis
- Scope and efficacy of the broad-spectrum topical antiseptic choline geranate
- Hematological and biochemical parameters for Chinese rhesus macaque
- Veterinary peer study groups as a method of continuous education—A new approach to identify and address factors associated with antimicrobial prescribing
- Correction: The prognosis of heart failure patients: Does sodium level play a significant role?
- Maternal malaria but not schistosomiasis is associated with a higher risk of febrile infection in infant during the first 3 months of life: A mother-child cohort in Benin
- Systematic identification of facility-based stillbirths and neonatal deaths through the piloted use of an adapted RAPID tool in Liberia and Nepal
- Effects of salbutamol and phlorizin on acute pulmonary inflammation and disease severity in experimental sepsis
- Correction: Age, sex and storage time influence hair cortisol levels in a wild mammal population
- Reasons to care: Personal motivation as a key factor in the practice of the professional foster carer in Romania
- Determinants of clinical, functional and personal recovery for people with schizophrenia and other severe mental illnesses: A cross-sectional analysis
- Continuity of care for TB patients at a South African hospital: A qualitative participatory study of the experiences of hospital staff
- EGF receptor stimulation shifts breast cancer cell glucose metabolism toward glycolytic flux through PI3 kinase signaling
- The Better Management of Patients with Osteoarthritis Program: Outcomes after evidence-based education and exercise delivered nationwide in Sweden
- The negative effects of short-term extreme thermal events on the seagrass Posidonia oceanica are exacerbated by ammonium additions
- Pathogen invasion history elucidates contemporary host pathogen dynamics
- Chinese herbal formulae for the treatment of menopausal hot flushes: A systematic review and meta-analysis
- Healthcare resource utilization and costs for multiple sclerosis management in the Campania region of Italy: Comparison between centre-based and local service healthcare delivery
- Deconstruction of central line insertion guidelines based on the positive deviance approach—Reducing gaps between guidelines and implementation: A qualitative ethnographic research
- PBMCs transcriptome profiles identified breed-specific transcriptome signatures for PRRSV vaccination in German Landrace and Pietrain pigs
- The impact of admission serum lactate on children with moderate to severe traumatic brain injury
- Hypervirulent Klebsiella pneumoniae serotype K1 clinical isolates form robust biofilms at the air-liquid interface
- Determination of the bruise degree for cherry using Vis-NIR reflection spectroscopy coupled with multivariate analysis
- Genome-wide identification and expression profile analysis of nuclear factor Y family genes in Sorghum bicolor L. (Moench)
- Trends in maternal prepregnancy body mass index (BMI) and its association with birth and maternal outcomes in California, 2007–2016: A retrospective cohort study
- Distribution of the Duffy genotypes in Malaysian Borneo and its relation to Plasmodium knowlesi malaria susceptibility
- Hippocampal connectivity with sensorimotor cortex during volitional finger movements: Laterality and relationship to motor learning
- A self-adaptive deep learning method for automated eye laterality detection based on color fundus photography
- The effect of child marriage on the utilization of maternal health care in Nepal: A cross-sectional analysis of Demographic and Health Survey 2016
- Identification of QTLs for powdery mildew (Podosphaera aphanis; syn. Sphaerotheca macularis f. sp. fragariae) susceptibility in cultivated strawberry (Fragaria ×ananassa)
- Chemical volatiles present in cotton gin trash: A by-product of cotton processing
- PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils
- Differential metabolomics networks analysis of menopausal status
- Experimental study of the temporal profile of breath alcohol concentration in a Chinese population after a light meal
- Association between regional brain volumes and BMI z-score change over one year in children
- Relationships between Potentially Toxic Elements in intertidal sediments and their bioaccumulation by benthic invertebrates
- Long-term outcomes of dialysis in patients with chronic kidney disease and new-onset atrial fibrillation: A population-based cohort study
- Hospital burden of pulmonary arterial hypertension in France
- Understanding the variability of Australian fire weather between 1973 and 2017
- Photon-counting cine-cardiac CT in the mouse
- Ecophysiological impacts of Esca, a devastating grapevine trunk disease, on Vitis vinifera L.
- Black “Reading the Mind in the Eyes” task: The development of a task assessing mentalizing from black faces
- Osmolytes ameliorate the effects of stress in the absence of the heat shock protein Hsp104 in Saccharomyces cerevisiae
- Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects
- Validation of the Rainbow Model of Integrated Care Measurement Tools (RMIC-MTs) in renal care for patient and care providers
- Multiple origins and the population genetic structure of Rubus takesimensis (Rosaceae) on Ulleung Island: Implications for the genetic consequences of anagenetic speciation
- Genetic profiling of fatty acid desaturase polymorphisms identifies patients who may benefit from high-dose omega-3 fatty acids in cardiac remodeling after acute myocardial infarction—Post-hoc analysis from the OMEGA-REMODEL randomized controlled trial
- A randomized controlled trial examining the efficacy of an internet-based cognitive behavioral therapy program for adolescents with anxiety disorders
- Optimising outputs from a validated online instrument to measure health-related quality of life (HRQL) in dogs
- Young adults’ perceptions of using wearables, social media and other technologies to detect worsening mental health: A qualitative study
- Characteristics of prescription in 29 Level 3 Neonatal Wards over a 2-year period (2017-2018). An inventory for future research
- Genetic characterization of fall armyworm (Spodoptera frugiperda) in Ecuador and comparisons with regional populations identify likely migratory relationships
- Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
- Cardiac resynchronization therapy-heart failure (CRT-HF) clinic: A novel model of care
- Synteny and phylogenetic analysis of paralogous thyrostimulin beta subunits (GpB5) in vertebrates
- Dual-Subpopulation as reciprocal optional external archives for differential evolution
- NGS analysis in Marfan syndrome spectrum: Combination of rare and common genetic variants to improve genotype-phenotype correlation analysis
- Optimization of cataract surgery follow-up: A standard set of questions can predict unexpected management changes at postoperative week one
- Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial
- Clinical evaluation of General Electric new Swiftscan solution in bone scintigraphy on NaI-camera: A head to head comparison with Siemens Symbia
- Pharmacist-led academic detailing improves statin therapy prescribing for Malaysian patients with type 2 diabetes: Quasi-experimental design
- Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor
- Clinical outcomes with neoadjuvant versus adjuvant chemotherapy for triple negative breast cancer: A report from the National Cancer Database
- Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function
- Wikipedia network analysis of cancer interactions and world influence
- Using path signatures to predict a diagnosis of Alzheimer’s disease
- Development and verification of prediction models for preventing cardiovascular diseases
- Additive and heterozygous (dis)advantage GWAS models reveal candidate genes involved in the genotypic variation of maize hybrids to Azospirillum brasilense
- Fish tank granuloma: An emerging skin disease in Iran mimicking Cutaneous Leishmaniasis
- Transience effect in capture-recapture studies: The importance of its biological meaning
- Detailed global modelling of soil organic carbon in cropland, grassland and forest soils
- Oral dosing for antenatal corticosteroids in the Rhesus macaque
- Retraction: Modulation of the Pentose Phosphate Pathway Induces Endodermal Differentiation in Embryonic Stem Cells
- An analysis on HBsAg, Anti-HCV, Anti-HIV½ and VDRL test results in blood donors according to gender, age range and years
- Clinical factors associated with bacterial translocation in Japanese patients with type 2 diabetes: A retrospective study
- Meaningful work and resilience among teachers: The mediating role of work engagement and job crafting
- The conditional Fama-French model and endogenous illiquidity: A robust instrumental variables test
- Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes
- Characterization of sequentially-staged cancer cells using electrorotation
- Vancomycin-laden calcium phosphate-calcium sulfate composite allows bone formation in a rat infection model
- Genetic evidence for plural introduction pathways of the invasive weed Paterson’s curse (Echium plantagineum L.) to southern Australia
- Risk of major autoimmune diseases in female breast cancer patients: A nationwide, population-based cohort study
- Real-time three-dimensional MRI for the assessment of dynamic carpal instability
- Interim report on the effective intraperitoneal therapy of insulin-dependent diabetes mellitus in pet dogs using “Neo-Islets,” aggregates of adipose stem and pancreatic islet cells (INAD 012-776)
- The frequency of bowel and bladder problems in multiple sclerosis and its relation to fatigue: A single centre experience
- Retraction: Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection
- The association between role model presence and self-regulation in early adolescence: A cross-sectional study
- Correction: A controlled-release oral opioid supports S. aureus survival in injection drug preparation equipment and may increase bacteremia and endocarditis risk
- Methamphetamine regulation of activity and topology of ventral midbrain networks
- Evaluation and treatment of latent tuberculosis infection among healthcare workers in Korea: A multicentre cohort analysis
- Occult periprosthetic femoral fractures occur frequently during a long, trapezoidal, double-tapered cementless femoral stem fixation in primary THA
- TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer
- Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation
- Comparing infiltration rates in soils managed with conventional and alternative farming methods: A meta-analysis
- Correction: Permissivity of Primary Human Hepatocytes and Different Hepatoma Cell Lines to Cell Culture Adapted Hepatitis C Virus
- Radiomics features of the primary tumor fail to improve prediction of overall survival in large cohorts of CT- and PET-imaged head and neck cancer patients
- The complete mitochondrial genome of Calyptogena marissinica (Heterodonta: Veneroida: Vesicomyidae): Insight into the deep-sea adaptive evolution of vesicomyids
- Correction: In vitro larval rearing protocol for the stingless bee species Melipona scutellaris for toxicological studies
- Correction: Morphological and molecular identification of the dioecious “African species Volvox rousseletii (Chlorophyceae) in the water column of a Japanese lake based on field-collected and cultured materials
- Upper versus lower airway microbiome and metagenome in children with cystic fibrosis and their correlation with lung inflammation
- “…or else I close my ears” How women with obesity want to be approached and treated regarding gestational weight management: A qualitative interview study
- Does a spinal implant alter dual energy X-ray absorptiometry body composition measurements?
- Economic and livestock health impacts of birds on dairies: Evidence from a survey of Washington dairy operators
- Repair of subtotal tympanic membrane perforations: A temporal bone study of several tympanoplasty materials
- Shifts in temperature influence how Batrachochytrium dendrobatidis infects amphibian larvae
- Sequential two-step chromatographic purification of infectious poliovirus using ceramic fluoroapatite and ceramic hydroxyapatite columns
- Frequency and distribution of corneal astigmatism and keratometry features in adult life: Methodology and findings of the UK Biobank study
- Differences in the impedance of cochlear implant devices within 24 hours of their implantation
- Suppressive impact of metronomic chemotherapy using UFT and/or cyclophosphamide on mediators of breast cancer dissemination and invasion
- Expression of Concern: miRNA 17 Family Regulates Cisplatin-Resistant and Metastasis by Targeting TGFbetaR2 in NSCLC
- Group leaders establish cooperative norms that persist in subsequent interactions
- Addis Ababa population-based pattern of cancer therapy, Ethiopia
- Agreement between the Cochrane risk of bias tool and Physiotherapy Evidence Database (PEDro) scale: A meta-epidemiological study of randomized controlled trials of physical therapy interventions
- Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development
- DNA barcoding of coastal ray-finned fishes in Vietnam
- Comparison of climbing-specific strength and endurance between lead and boulder climbers
- The performance of different case definitions for severe influenza surveillance among HIV-infected and HIV-uninfected children aged <5 years in South Africa, 2011–2015
- Analgesic drug use in elderly persons: A population-based study in Southern Italy
- RCER: Reliable Cluster-based Energy-aware Routing protocol for heterogeneous Wireless Sensor Networks
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