Relationship between Helicobacter pylori infection and obesity in Chinese adults: A systematic review with meta-analysis
Autoři:
Xinlan Xu aff001; Weide Li aff001; Lan Qin aff001; Wenjiao Yang aff002; Guowei Yu aff003; Qishan Wei aff004
Působiště autorů:
School of Mathematics and Statistics, Lanzhou University, Lanzhou, Gansu, China
aff001; School of Public Health, Lanzhou University, Lanzhou, Gansu, China
aff002; Medical College of Northwest University for Nationalities, Lanzhou, Gansu, China
aff003; Maternal and Child Health Hospital, Lanzhou, Gansu, China
aff004
Vyšlo v časopise:
PLoS ONE 14(9)
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pone.0221076
Souhrn
Background
Obesity is highly prevalent worldwide. More and more studies have been conducted on the relationship between H. pylori infection and obesity or overweight. But the relationship between them is controversial in the literatures and there is no comprehensive evidence for the correlation.
Aim
To evaluate the prevalence of H. pylori infection in Chinese adult subjects who received routine physical examinations and the relationship between H. pylori and obesity.
Methods
Literatures on H. pylori infection and obesity in Chinese population were searched in online databases. Relevant data were extracted independently by two researchers and meta-analysis was performed by using Review manager 5.3 software.
Results
22 articles were selected with a total sample size of 178033. The pooled prevalence of H. pylori was 42% (95%CI: 37% to 47%) and mean difference of BMI between subjects with and without H. pylori infection was 0.94 (95%CI: -0.04 to 1.91). 9 eligible studies with 27111 subjects were used to calculated pooled OR value because they contained obesity groups. The OR value showed that H. pylori-positive subjects tended to be obese at a risk of 1.20 (95% CI: 1.13 to 1.28).
Conclusion
In China, obesity has association with H. pylori infection. H. pylori infection may be one of the risk factors for obesity.
Klíčová slova:
Body Mass Index – Helicobacter pylori – Biology and life sciences – Biochemistry – Organisms – Physical sciences – Research and analysis methods – Database and informatics methods – Mathematics – Medicine and health sciences – Microbiology – Medical microbiology – Microbial pathogens – Bacterial pathogens – Bacteria – Pathology and laboratory medicine – Pathogens – Physiology – Physiological parameters – Body weight – Infectious diseases – Bacterial diseases – Statistics – Mathematical and statistical techniques – Statistical methods – Metaanalysis – Research design – Lipids – Cholesterol – Obesity – Database searching – Helicobacter – Helicobacter pylori infection – Cross-sectional studies
Zdroje
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