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Hematological and biochemical parameters for Chinese rhesus macaque


Autoři: Wenhai Yu aff001;  Xianhui Hao aff002;  Fengmei Yang aff001;  Jin Ma aff001;  Yuan Zhao aff001;  Yanyan Li aff001;  Junbin Wang aff001;  Hongjie Xu aff001;  Lixiong Chen aff001;  Quan Liu aff001;  Suqin Duan aff001;  Yaping Yang aff001;  Fen Huang aff002;  Zhanlong He aff001
Působiště autorů: Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, PR China aff001;  Medical Faculty, Kunming University of Science and Technology, Kunming, PR China aff002
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0222338

Souhrn

Rhesus macaque is an important animal model in biomedical research, especially human disease, developmental, translational, and pre-clinical research. Blood physiological and biochemical parameters are important markers for physiology, pathology, and toxicology research. However, these parameters have not been systematically reported for Chinese rhesus macaques. To characterize the reference for these parameters, this study collected 1805 Chinese rhesus macaques living in Southwestern China. A total of 24 blood physiological indexes and 27 biochemical parameters were determined. Sex and age were found to affect these parameters. In conclusion, a comprehensive and systematic reference of hematological and biochemical parameters for Chinese rhesus macaque was established in this work on the basis of a large cohort. Such reference will benefit biomedical research employing rhesus macaques as animal models.

Klíčová slova:

Biology and life sciences – Biochemistry – Organisms – Eukaryota – Physical sciences – Research and analysis methods – Animal studies – Experimental organism systems – Proteins – Animals – Animal models – People and places – Population groupings – Mathematics – Anatomy – Medicine and health sciences – Physiology – Vertebrates – Amniotes – Mammals – Statistics – Mathematical and statistical techniques – Statistical methods – Immunology – Immune physiology – Body fluids – Blood – Hematology – Immune system proteins – Antibodies – Analysis of variance – Age groups – Primates – Monkeys – Old World monkeys – Macaque – Rhesus monkeys


Zdroje

1. Heald AE, Charleston JS, Iversen PL, Warren TK, Saoud JB, Al-Ibrahim M, et al. AVI-7288 for Marburg Virus in Nonhuman Primates and Humans. The New England journal of medicine. 2015;373(4):339–48. Epub 2015/07/23. doi: 10.1056/NEJMoa1410345 26200980.

2. Davey RT Jr, Dodd L, Proschan MA, Neaton J, Neuhaus Nordwall J, Koopmeiners JS, et al. A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection. The New England journal of medicine. 2016;375(15):1448–56. Epub 2016/10/13. doi: 10.1056/NEJMoa1604330 PubMed Central PMCID: PMC5086427. 27732819

3. Harding JD. Genomic Tools for the Use of Nonhuman Primates in Translational Research. ILAR journal. 2017;58(1):59–68. Epub 2017/08/26. doi: 10.1093/ilar/ilw042 28838069.

4. Coleman K, Pierre PJ. Assessing anxiety in nonhuman primates. ILAR journal. 2014;55(2):333–46. Epub 2014/09/17. doi: 10.1093/ilar/ilu019 25225310; PubMed Central PMCID: PMC4240439.

5. Moody DB, Stebbins WC, Hawkins JE Jr, Johnsson LG. Hearing loss and cochlear pathology in the monkey (Macaca) following exposure to high levels of noise. Archives of oto-rhino-laryngology. 1978;220(1–2):47–72. Epub 1978/03/03. 417707.

6. Pennisi E. Boom time for monkey research. Science (New York, NY). 2007;316(5822):216–8. Epub 2007/04/14. doi: 10.1126/science.316.5822.216 17431165.

7. Antony JM, MacDonald KS. A critical analysis of the cynomolgus macaque, Macaca fascicularis, as a model to test HIV-1/SIV vaccine efficacy. Vaccine. 2015;33(27):3073–83. Epub 2014/12/17. doi: 10.1016/j.vaccine.2014.12.004 25510387.

8. Kuiken T, Buijs P, van Run P, van Amerongen G, Koopmans M, van den Hoogen B. Pigeon paramyxovirus type 1 from a fatal human case induces pneumonia in experimentally infected cynomolgus macaques (Macaca fascicularis). Veterinary research. 2017;48(1):80. Epub 2017/11/23. doi: 10.1186/s13567-017-0486-6 29162154; PubMed Central PMCID: PMC5697235.

9. Schmitt CA, Service SK, Jasinska AJ, Dyer TD, Jorgensen MJ, Cantor RM, et al. Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus). International journal of obesity (2005). 2017. Epub 2017/12/07. doi: 10.1038/ijo.2017.301 29211707.

10. Eastman AJ, Bergin IL, Chai D, Bassis CM, LeBar W, Oluoch GO, et al. Impact of the Levonorgestrel-Releasing Intrauterine System on the Progression of Chlamydia trachomatis Infection to Pelvic Inflammatory Disease in a Baboon Model. The Journal of infectious diseases. 2017. Epub 2017/12/19. doi: 10.1093/infdis/jix545 29253201.

11. Hirano Y, Yen CC, Liu JV, Mackel JB, Merkle H, Nascimento GC, et al. Investigation of the BOLD and CBV fMRI responses to somatosensory stimulation in awake marmosets (Callithrix jacchus). 2017. doi: 10.1002/nbm.3864 29285809.

12. Magness CL, Fellin PC, Thomas MJ, Korth MJ, Agy MB, Proll SC, et al. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Genome Biol. 2005;6(7):R60. Epub 2005/07/07. doi: 10.1186/gb-2005-6-7-r60 15998449; PubMed Central PMCID: PMC1175991.

13. Ibanez-Contreras A, Hernandez-Arciga U, Poblano A, Arteaga-Silva M, Hernandez-Godinez B, Mendoza-Cuevas GI, et al. Electrical activity of sensory pathways in female and male geriatric Rhesus monkeys (Macaca mulatta), and its relation to oxidative stress. Experimental gerontology. 2017;101:80–94. Epub 2017/11/18. doi: 10.1016/j.exger.2017.11.003 29146475.

14. Rao M, Ma S, Hu S, Lei H, Wu Y, Zhou Y, et al. Isobaric tags for relative and absolute quantification-based proteomic analysis of testis biopsies in rhesus monkeys treated with transient scrotal hyperthermia. Oncotarget. 2017;8(49):85909–25. Epub 2017/11/22. doi: 10.18632/oncotarget.20719 29156766; PubMed Central PMCID: PMC5689656.

15. Aoyama A, Tonsho M, Ng CY, Lee S, Millington T, Nadazdin O, et al. Long-term lung transplantation in nonhuman primates. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2015;15(5):1415–20. Epub 2015/03/17. doi: 10.1111/ajt.13130 25772308; PubMed Central PMCID: PMC4564890.

16. Pinto-Santini DM, Stenbak CR, Linial ML. Foamy virus zoonotic infections. Retrovirology. 2017;14(1):55. Epub 2017/12/05. doi: 10.1186/s12977-017-0379-9 29197389.

17. Hu Y, Song J, Liu L, Li J, Tang B, Wang J, et al. Different microRNA alterations contribute to diverse outcomes following EV71 and CA16 infections: Insights from high-throughput sequencing in rhesus monkey peripheral blood mononuclear cells. The international journal of biochemistry & cell biology. 2016;81(Pt A):20–31. Epub 2016/10/30. doi: 10.1016/j.biocel.2016.10.011 27765603.

18. Cheng CH, Guo ZX, Luo SW, Wang AL. Effects of high temperature on biochemical parameters, oxidative stress, DNA damage and apoptosis of pufferfish (Takifugu obscurus). Ecotoxicology and environmental safety. 2017;150:190–8. Epub 2017/12/26. doi: 10.1016/j.ecoenv.2017.12.045 29276954.

19. He Q, Su G, Liu K. Sex-specific reference intervals of hematologic and biochemical analytes in Sprague-Dawley rats using the nonparametric rank percentile method. 2017;12(12):e0189837. doi: 10.1371/journal.pone.0189837 29261747.

20. Xie L, Xu F, Liu S, Ji Y, Zhou Q, Wu Q, et al. Age- and sex-based hematological and biochemical parameters for Macaca fascicularis. PloS one. 2013;8(6):e64892. Epub 2013/06/14. doi: 10.1371/journal.pone.0064892 23762263; PubMed Central PMCID: PMC3677909.

21. Perretta G, Violante A, Scarpulla M, Beciani M, Monaco V. Normal serum biochemical and hematological parameters in Macaca fascicularis. Journal of medical primatology. 1991;20(7):345–51. Epub 1991/09/01. 1787529.

22. Kozlosky JC, Mysore J, Clark SP, Burr HN, Li J, Aranibar N, et al. Comparison of physiologic and pharmacologic parameters in Asian and mauritius cynomolgus macaques. Regulatory toxicology and pharmacology: RTP. 2015;73(1):27–42. Epub 2015/06/27. doi: 10.1016/j.yrtph.2015.06.008 26111605.

23. Thierry B, Andre E, Imbs P. Hematologic and plasma biochemical values for Tonkean macaques (Macaca tonkeana). Journal of zoo and wildlife medicine: official publication of the American Association of Zoo Veterinarians. 2000;31(2):179–84. Epub 2000/09/12. doi: 10.1638/1042-7260(2000)031[0179:hapbvf]2.0.co;2 10982129.

24. Lee JI, Shin JS, Lee JE, Jung WY, Lee G, Kim MS, et al. Reference values of hematology, chemistry, electrolytes, blood gas, coagulation time, and urinalysis in the Chinese rhesus macaques (Macaca mulatta). Xenotransplantation. 2012;19(4):244–8. Epub 2012/08/23. doi: 10.1111/j.1399-3089.2012.00713.x 22909137.

25. Goodrich JA, Ward GS, Swindle MM. Normal serum biochemical and hematological values of the Sulawesi macaques. Journal of medical primatology. 1995;24(1):17–28. Epub 1995/01/01. 7563007.

26. Chen Y, Qin S, Ding Y, Wei L, Zhang J, Li H, et al. Reference values of clinical chemistry and hematology parameters in rhesus monkeys (Macaca mulatta). Xenotransplantation. 2009;16(6):496–501. Epub 2010/01/01. doi: 10.1111/j.1399-3089.2009.00554.x 20042049.

27. Redlberger S, Fischer S, Kohler H, Diller R, Reinhold P. Age-dependent physiological dynamics in acid-base balance, electrolytes, and blood metabolites in growing goats. Veterinary journal (London, England: 1997). 2017;229:45–52. Epub 2017/12/01. doi: 10.1016/j.tvjl.2017.10.017 29183573.

28. Shen G, Tian JD, Guo XB, Wang H, F, Lu JQ. Hemogram and Blood Biochemical parameters of Taihangshan in Jiyuan, Chian. Sichuan Journal of Zoolgy. 2011;30(2):254–7.

29. Dai JJ, Tang D, H, Lu SY, Kuang DX, Yang F, Cheng SJ, et al. Clinica normal value of hematology and serum biochemistry in domestically bred and reared rhesus moneky Acta laboratorium scientia sinica. 2000;8(4):224–30.

30. Mauvais-Jarvis F. Gender differences in glucose homeostasis and diabetes. Physiology & behavior. 2018;187:20–3. Epub 2017/08/28. doi: 10.1016/j.physbeh.2017.08.016 28843891; PubMed Central PMCID: PMC5826763.

31. Wang Z, Ii C, Liu Z, Lu Z, Liu Y, Mei QB, et al. Some Indexes of Physiology,Hematology,Serum Biochemistry,Immunology in Macaca Mulatto Monkeys Progress in Veterinary Medicine. 2005;26(8):68–71.

32. Hallan S, Euser AM, Irgens LM, Finken MJ, Holmen J, Dekker FW. Effect of intrauterine growth restriction on kidney function at young adult age: the Nord Trondelag Health (HUNT 2) Study. American journal of kidney diseases: the official journal of the National Kidney Foundation. 2008;51(1):10–20. Epub 2007/12/25. doi: 10.1053/j.ajkd.2007.09.013 18155528.

33. Li S, Chen SC, Shlipak M, Bakris G, McCullough PA, Sowers J, et al. Low birth weight is associated with chronic kidney disease only in men. Kidney international. 2008;73(5):637–42. Epub 2007/12/21. doi: 10.1038/sj.ki.5002747 18094674.

34. Loria A, Reverte V, Salazar F, Saez F, Llinas MT, Salazar FJ. Sex and age differences of renal function in rats with reduced ANG II activity during the nephrogenic period. American journal of physiology Renal physiology. 2007;293(2):F506–10. Epub 2007/04/20. doi: 10.1152/ajprenal.00066.2007 17442728.

35. Black MJ, Lim K, Zimanyi MA, Sampson AK, Bubb KJ, Flower RL, et al. Accelerated age-related decline in renal and vascular function in female rats following early-life growth restriction. American journal of physiology Regulatory, integrative and comparative physiology. 2015;309(9):R1153–61. Epub 2015/09/18. doi: 10.1152/ajpregu.00403.2014 26377562.

36. Nikkila M, Pitkajarvi T, Koivula T, Solakivi T, Lehtimaki T, Laippala P, et al. Women have a larger and less atherogenic low density lipoprotein particle size than men. Atherosclerosis. 1996;119(2):181–90. Epub 1996/01/26. doi: 10.1016/0021-9150(95)05645-9 8808495.

37. Miller AA, De Silva TM, Jackman KA, Sobey CG. Effect of gender and sex hormones on vascular oxidative stress. Clinical and experimental pharmacology & physiology. 2007;34(10):1037–43. Epub 2007/08/24. doi: 10.1111/j.1440-1681.2007.04732.x 17714091.

38. Lemieux I, Pascot A, Lamarche B, Prud'homme D, Nadeau A, Bergeron J, et al. Is the gender difference in LDL size explained by the metabolic complications of visceral obesity? European journal of clinical investigation. 2002;32(12):909–17. Epub 2003/01/22. doi: 10.1046/j.1365-2362.2002.01092.x 12534450.

39. Clarke EV, Tenner AJ. Complement modulation of T cell immune responses during homeostasis and disease. Journal of leukocyte biology. 2014;96(5):745–56. Epub 2014/09/12. doi: 10.1189/jlb.3MR0214-109R 25210145; PubMed Central PMCID: PMC4197570.

40. Finkelman FD, Khodoun MV, Strait R. Human IgE-independent systemic anaphylaxis. The Journal of allergy and clinical immunology. 2016;137(6):1674–80. Epub 2016/05/01. doi: 10.1016/j.jaci.2016.02.015 27130857.

41. Martin M, Blom AM. Complement in removal of the dead—balancing inflammation. Immunological reviews. 2016;274(1):218–32. Epub 2016/10/27. doi: 10.1111/imr.12462 27782329.

42. Wouters D, Zeerleder S. Complement inhibitors to treat IgM-mediated autoimmune hemolysis. Haematologica. 2015;100(11):1388–95. Epub 2015/11/02. doi: 10.3324/haematol.2015.128538 26521297; PubMed Central PMCID: PMC4825292.

43. Arnold JN, Dwek RA, Rudd PM, Sim RB. Mannan binding lectin and its interaction with immunoglobulins in health and in disease. Immunology letters. 2006;106(2):103–10. Epub 2006/07/04. doi: 10.1016/j.imlet.2006.05.007 16814399.

44. Loh RK, Vale S, McLean-Tooke A. Quantitative serum immunoglobulin tests. Australian family physician. 2013;42(4):195–8. Epub 2013/04/04. 23550242.

45. Pucic M, Muzinic A, Novokmet M, Skledar M, Pivac N, Lauc G, et al. Changes in plasma and IgG N-glycome during childhood and adolescence. Glycobiology. 2012;22(7):975–82. Epub 2012/03/20. doi: 10.1093/glycob/cws062 22426998.

46. Kristic J, Vuckovic F, Menni C, Klaric L, Keser T, Beceheli I, et al. Glycans are a novel biomarker of chronological and biological ages. The journals of gerontology Series A, Biological sciences and medical sciences. 2014;69(7):779–89. Epub 2013/12/12. doi: 10.1093/gerona/glt190 24325898; PubMed Central PMCID: PMC4049143.

47. Khalil R, Kim NR, Jardi F, Vanderschueren D, Claessens F, Decallonne B. Sex steroids and the kidney: role in renal calcium and phosphate handling. Mol Cell Endocrinol. 2018;465:61–72. Epub 2017 Nov 16. doi: 10.1016/j.mce.2017.11.011 29155307.

48. Buchl SJ, Howard B. Hematologic and serum biochemical and electrolyte values in clinically normal domestically bred rhesus monkeys (Macaca mulatta) according to age, sex, and gravidity. Laboratory animal science. 1997;47(5):528–33. Epub 1997/11/14. 9355097.

49. Sato A, Fairbanks LA, Lawson T, Lawson GW. Effects of age and sex on hematologic and serum biochemical values of vervet monkeys (Chlorocebus aethiops sabaeus). Contemporary topics in laboratory animal science. 2005;44(1):29–34. Epub 2005/02/09. 15697196.

50. Berger M, Calapai A, Stephan V, Niessing M, Burchardt L, Gail A, et al. Standardized automated training of rhesus monkeys for neuroscience research in their housing environment. Journal of neurophysiology. 2017:jn.00614.2017. Epub 2017/11/17. doi: 10.1152/jn.00614.2017 29142094.

51. Hauser SN, Burton JA, Mercer ET, Ramachandran R. Effects of noise overexposure on tone detection in noise in nonhuman primates. Hearing research. 2017;357:33–45. Epub 2017/11/28. doi: 10.1016/j.heares.2017.11.004 29175767.

52. Jardim Paz MFC, Junior ALG, Islam MT, Tabrez S, Jabir NR, Alam MZ, et al. Assessment of chemotherapy on various biochemical markers in breast cancer patients. Journal of cellular biochemistry. 2017. Epub 2017/11/10. doi: 10.1002/jcb.26487 29120088.

53. John WS, Martin TJ, Solingapuram Sai KK, Nader SH, Gage HD, Mintz A, et al. CHRONIC Delta9-THC IN RHESUS MONKEYS: EFFECTS ON COGNITIVE PERFORMANCE AND DOPAMINE D2/D3 RECEPTOR AVAILABILITY. The Journal of pharmacology and experimental therapeutics. 2017. Epub 2017/12/06. doi: 10.1124/jpet.117.244194 29203575.

54. Kodihalli S, Emanuel A, Takla T, Hua Y, Hobbs C, LeClaire R, et al. Therapeutic efficacy of equine botulism antitoxin in Rhesus macaques. PloS one. 2017;12(11):e0186892. Epub 2017/11/23. doi: 10.1371/journal.pone.0186892 29166654.

55. Huang F, Li Y, Yu W, Jing S, Wang J, Long F, et al. Excretion of infectious hepatitis E virus into milk in cows imposes high risks of zoonosis. Hepatology. 2016;64(2):350–9. Epub 2016/06/12. doi: 10.1002/hep.28668 27286751.

56. Zhao T, Zhang Z, Zhang Y, Feng M, Fan S, Wang L, et al. Dynamic Interaction of Enterovirus 71 and Dendritic Cells in Infected Neonatal Rhesus Macaques. Frontiers in cellular and infection microbiology. 2017;7:171. Epub 2017/05/26. doi: 10.3389/fcimb.2017.00171 28540257; PubMed Central PMCID: PMC5423916.

57. Kimura T, Koike T, Matsunaga T, Sazi T, Hiroe T, Kubota M. Evaluation of a medetomidine-midazolam combination for immobilizing and sedating Japanese monkeys (Macaca fuscata). Journal of the American Association for Laboratory Animal Science: JAALAS. 2007;46(4):33–8. Epub 2007/07/25. 17645293.

58. Koga T, Kanefuji K, Nakama K. Individual reference intervals of hematological and serum biochemical parameters in cynomolgus monkeys. International journal of toxicology. 2005;24(5):377–85. Epub 2005/11/01. doi: 10.1080/10915810500208058 16257857.


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